Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Oct. 25, 2023
Regular
physical
effort
produces
metabolic
changes
manifested
as
adaptation
to
exercise
and
increasing
performance.
In
humans
these
have
been
characterized
at
metabolome
level
depending
on
the
discipline.
However,
all
sports
involve
some
of
in
protein,
carbohydrate
lipid
metabolism.
Recently,
also
performance
horses
subjected
analyses,
but
similar
studies
were
lacking
dogs.
this
study
we
performed
metabolomic
analysis
plasma
Whippet
dogs
regularly
trained
competing
coursing
events,
untrained
same
breed,
fed
with
diet.
We
compared
hematological
blood
biochemical
results
two
groups
Basic
tests
indicated
that
enzymes
related
metabolism
(lipase
gamma-glutamyltransferase)
differed
considerably
between
groups.
Metabolomic
confirmed
shift
expressed
differences
triacylglycerols
levels
training
non-training
dogs,
aimed
improving
use
fatty
acids
a
source
energy
during
exertion.
Surprisingly,
other
classes
metabolites
only
hardly
changed
when
comparing
Whippets.
Frontiers in Physiology,
Journal Year:
2023,
Volume and Issue:
14
Published: Nov. 15, 2023
Objective:
Sweat
is
an
important
specimen
of
human
metabolism,
which
can
simply
and
non-invasively
monitor
the
metabolic
state
body,
its
metabolites
be
used
as
biomarkers
for
disease
diagnosis,
while
changes
sweat
before
after
exercise-induced
fatigue
are
still
unclear.
Methods:
In
this
experiment,
high-performance
chemical
isotope
labeling
liquid
chromatography-mass
spectrometry
(LC-MS)
was
to
metabolomic
28
samples
14
long-distance
runners,
also
IsoMS
PRO
SPSS22.0
software
were
analyze
metabolite
differential
pathways.
Results:
A
total
446
with
high
confidence
identified,
metabolome
group
high-intensity
interval
obvious,
among
upregulated
mainly
included
hypoxanthine,
pyruvate,
several
amino
acids,
etc.,
downregulated
acid
derivatives,
vitamin
B6,
theophylline,
etc.
Conclusion:
The
change
hypoxanthine
concentration
in
a
good
biomarker
diagnosis
fatigue,
pyruvate
content
discriminant
index
energy
metabolism
mode
body
exercise.
main
pathways
involved
produced
HIIT
purine
metabolism.
Balneo and PRM Research Journal,
Journal Year:
2023,
Volume and Issue:
Vol.14, no.3, P. 581 - 581
Published: Sept. 1, 2023
Biomarkers
have
emerged
as
valuable
tools
in
the
realm
of
elite
sports,
providing
objective
measures
athletes'
physiological
responses
and
potential
for
performance
optimization.
This
article
review
delves
into
significance
implications
biomarkers
emphasizing
their
crucial
role
supporting
training,
recovery,
overall
success.
The
integration
offers
unprecedented
opportunities
evidence-based
decisions,
personalized
strategies,
injury
prevention,
revolutionizing
landscape
sports.
Through
comprehensive
literature
analysis,
this
highlights
tremendous
promise
optimizing
athletic
while
also
addressing
ethical
considerations
surrounding
implementation.
As
research
continues
to
advance,
are
poised
reshape
future
enhancing
paving
way
next
generation
sporting
legends.
Scientific Reports,
Journal Year:
2023,
Volume and Issue:
13(1)
Published: Oct. 25, 2023
Regular
physical
effort
produces
metabolic
changes
manifested
as
adaptation
to
exercise
and
increasing
performance.
In
humans
these
have
been
characterized
at
metabolome
level
depending
on
the
discipline.
However,
all
sports
involve
some
of
in
protein,
carbohydrate
lipid
metabolism.
Recently,
also
performance
horses
subjected
analyses,
but
similar
studies
were
lacking
dogs.
this
study
we
performed
metabolomic
analysis
plasma
Whippet
dogs
regularly
trained
competing
coursing
events,
untrained
same
breed,
fed
with
diet.
We
compared
hematological
blood
biochemical
results
two
groups
Basic
tests
indicated
that
enzymes
related
metabolism
(lipase
gamma-glutamyltransferase)
differed
considerably
between
groups.
Metabolomic
confirmed
shift
expressed
differences
triacylglycerols
levels
training
non-training
dogs,
aimed
improving
use
fatty
acids
a
source
energy
during
exertion.
Surprisingly,
other
classes
metabolites
only
hardly
changed
when
comparing
Whippets.