Neural Regeneration Research,
Journal Year:
2024,
Volume and Issue:
20(12), P. 3349 - 3369
Published: Nov. 13, 2024
The
exchange
of
information
and
materials
between
organelles
plays
a
crucial
role
in
regulating
cellular
physiological
functions
metabolic
levels.
Mitochondria-associated
endoplasmic
reticulum
membranes
serve
as
physical
contact
channels
the
membrane
mitochondrial
outer
membrane,
formed
by
various
proteins
protein
complexes.
This
microstructural
domain
mediates
several
specialized
functions,
including
calcium
(Ca
2+
)
signaling,
autophagy,
morphology,
oxidative
stress
response,
apoptosis.
Notably,
dysregulation
Ca
signaling
mediated
mitochondria-associated
is
critical
factor
pathogenesis
neurological
diseases.
Certain
or
complexes
within
these
directly
indirectly
regulate
distance
mitochondria,
well
transduction
signaling.
Conversely,
influences
other
membrane-associated
functions.
These
can
vary
significantly
across
different
diseases—such
ischemic
stroke,
traumatic
brain
injury,
Alzheimer’s
disease,
Parkinson’s
amyotrophic
lateral
sclerosis,
Huntington’s
disease—and
their
respective
stages
progression.
Targeted
modulation
disease-related
pathways
functional
enhance
function
promote
regeneration
repair
damaged
neurons.
Therefore,
membranes-mediated
pivotal
pathological
progression
diseases
represents
significant
potential
therapeutic
target.
review
focuses
on
effects
distinct
roles
diseases,
specifically
highlighting
early
protective
neuronal
damage
that
result
from
prolonged
overload
deficiency.
article
provides
comprehensive
analysis
mechanisms
contributing
to
exploration
targets
for
promoting
neuroprotection
nerve
repair.
Plant Stress,
Journal Year:
2024,
Volume and Issue:
14, P. 100584 - 100584
Published: Aug. 30, 2024
The
interaction
between
biochar
application
and
calcium
ions
(Ca2+)
in
plants,
terms
of
activating
plant
defense
mechanism
would
be
useful
to
improve
resilience
sustainable
agriculture.
This
review
aims
highlight
the
possible
connection
biochar-induced
changes
soil
physicochemical
properties,
microbial
interactions,
Ca2+
dynamics,
ultimately
leading
promote
mechanisms.
We
are
also
interested
discuss
role
signaling
coordinating
responses
various
biotic
abiotic
stresses
such
as
pathogen
insects
attacks,
cold
or
heat
stress
drought
well
how
fluxes,
calcium-binding
proteins,
ion
channels
influenced
by
environment.
Furthermore,
we
examine
impact
on
pathways
it
can
prime
genes
strengthen
call
wall
barriers
immunity.
Despite
significant
progress,
there
is
a
need
for
interdisciplinary
collaboration
fully
sort
out
plants
induction
Advanced
imaging
techniques,
proteomics
omics
approaches
could
helpful
unlock
complex
signaling.
Overall,
this
contributes
substantially
literature
describing
relationship
providing
insights
into
novel
enhancing
mechanisms
development
agricultural
solutions.
Neural Regeneration Research,
Journal Year:
2024,
Volume and Issue:
20(12), P. 3349 - 3369
Published: Nov. 13, 2024
The
exchange
of
information
and
materials
between
organelles
plays
a
crucial
role
in
regulating
cellular
physiological
functions
metabolic
levels.
Mitochondria-associated
endoplasmic
reticulum
membranes
serve
as
physical
contact
channels
the
membrane
mitochondrial
outer
membrane,
formed
by
various
proteins
protein
complexes.
This
microstructural
domain
mediates
several
specialized
functions,
including
calcium
(Ca
2+
)
signaling,
autophagy,
morphology,
oxidative
stress
response,
apoptosis.
Notably,
dysregulation
Ca
signaling
mediated
mitochondria-associated
is
critical
factor
pathogenesis
neurological
diseases.
Certain
or
complexes
within
these
directly
indirectly
regulate
distance
mitochondria,
well
transduction
signaling.
Conversely,
influences
other
membrane-associated
functions.
These
can
vary
significantly
across
different
diseases—such
ischemic
stroke,
traumatic
brain
injury,
Alzheimer’s
disease,
Parkinson’s
amyotrophic
lateral
sclerosis,
Huntington’s
disease—and
their
respective
stages
progression.
Targeted
modulation
disease-related
pathways
functional
enhance
function
promote
regeneration
repair
damaged
neurons.
Therefore,
membranes-mediated
pivotal
pathological
progression
diseases
represents
significant
potential
therapeutic
target.
review
focuses
on
effects
distinct
roles
diseases,
specifically
highlighting
early
protective
neuronal
damage
that
result
from
prolonged
overload
deficiency.
article
provides
comprehensive
analysis
mechanisms
contributing
to
exploration
targets
for
promoting
neuroprotection
nerve
repair.
