Contribution of phenylpropanoid metabolism to plant development and plant–environment interactions

Journal of Integrative Plant Biology, Journal Year: 2020, Volume and Issue: 63(1), P. 180 - 209

Published: Dec. 16, 2020

Abstract Phenylpropanoid metabolism is one of the most important metabolisms in plants, yielding more than 8,000 metabolites contributing to plant development and plant–environment interplay. materialized during evolution early freshwater algae that were initiating terrestrialization land plants have evolved multiple branches this pathway, which give rise including lignin, flavonoids, lignans, phenylpropanoid esters, hydroxycinnamic acid amides, sporopollenin. Recent studies revealed many factors participate regulation metabolism, modulate homeostasis when undergo successive developmental processes are subjected stressful environments. In review, we summarize recent progress on elucidating contribution coordination interaction, metabolic flux redirection among diverse routes. addition, our review focuses at transcriptional, post‐transcriptional, post‐translational, epigenetic levels, response phytohormones biotic abiotic stresses.

Language: Английский

---

MYB72-dependent coumarin exudation shapes root microbiome assembly to promote plant health

Proceedings of the National Academy of Sciences, Journal Year: 2018, Volume and Issue: 115(22)

Published: April 23, 2018

Plant roots nurture a tremendous diversity of microbes via exudation photosynthetically fixed carbon sources. In turn, probiotic members the root microbiome promote plant growth and protect host against pathogens pests. Arabidopsis thaliana-Pseudomonas simiae WCS417 model system root-specific transcription factor MYB72 MYB72-controlled β-glucosidase BGLU42 emerged as important regulators beneficial rhizobacteria-induced systemic resistance (ISR) iron-uptake responses. regulates biosynthesis iron-mobilizing fluorescent phenolic compounds, after which activity is required for their excretion into rhizosphere. Metabolite fingerprinting revealed antimicrobial coumarin scopoletin dominant metabolite that produced in excreted rhizosphere MYB72- BGLU42-dependent manner. Shotgun-metagenome sequencing root-associated microbiota Col-0, myb72, mutant f6'h1 showed selectively impacts assembly microbial community We show inhibits soil-borne fungal Fusarium oxysporum Verticillium dahliae, while growth-promoting ISR-inducing rhizobacteria P. Pseudomonas capeferrum WCS358 are highly tolerant effect scopoletin. Collectively, our results demonstrate role coumarins point to scenario plants join forces trigger MYB72/BGLU42-dependent scopolin production excretion, resulting improved niche establishment partner immunity benefits plant.

Language: Английский

---

Lignin biosynthesis and its integration into metabolism

Current Opinion in Biotechnology, Journal Year: 2019, Volume and Issue: 56, P. 230 - 239

Published: March 23, 2019

Language: Английский

---

Biosynthesis and Regulation of Phenylpropanoids in Plants

Critical Reviews in Plant Sciences, Journal Year: 2017, Volume and Issue: 36(4), P. 257 - 290

Published: July 4, 2017

Phenylpropanoids are a large class of plant secondary metabolites derived from aromatic amino acids phenylalanine in most plants or tyrosine partial monocots. It mainly includes flavonoids, monolignols, phenolic acids, stilbenes, and coumarins. widely distributed the kingdom play vital roles development by acting as essential components cell walls, protectants against high light UV radiation, phytoalexins herbivores pathogens, floral pigments to mediate plant–pollinator interactions. In addition, phenylpropanoids possess diverse biological activities that beneficial human health. past decades, structure function biosynthetic pathways monolignols have been extensively studied. Recent results showed miR828, ta-siRNAs R2R3-MYBs critical regulatory phenylpropanoid biosynthesis through two modes: either miR828–MYB–phenylpropanoid cascade which MYB transcripts directly cleaved miR828–ta-siRNA–MYB–phenylpropanoid under mediation TAS4- MYB-derived ta-siRNAs. this review, we overview structure, pathway summarize complex mechanism with focus on cascades involving MYBs.

Language: Английский

---

The Structure and Function of Major Plant Metabolite Modifications

Molecular Plant, Journal Year: 2019, Volume and Issue: 12(7), P. 899 - 919

Published: June 11, 2019

Language: Английский

---

Phenylpropanoid Pathway Engineering: An Emerging Approach towards Plant Defense

Pathogens, Journal Year: 2020, Volume and Issue: 9(4), P. 312 - 312

Published: April 23, 2020

Pathogens hitting the plant cell wall is first impetus that triggers phenylpropanoid pathway for defense. The bifurcates into production of an enormous array compounds based on few intermediates shikimate in response to breaches by pathogens. whole metabolomic a complex network regulated multiple gene families and it exhibits refined regulatory mechanisms at transcriptional, post-transcriptional, post-translational levels. genes are involved anti-microbial as well signaling molecules. engineering metabolic has led new defense system which various have been proposed including salicylic acid antimicrobial mediated compounds. In recent years, some key players like phenylalanine ammonia lyases (PALs) from broad spectrum disease resistance (BSR) without yield penalties. Now we more evidence than ever, yet little understanding about pathway-based orchestrate rapid, coordinated induction defenses microbial attack. It not astonishing mutants regulator can show conflicting results. Therefore, precise interesting strategy aim profitably tailored plants. Here, this review portrays current progress challenges prospective provide deeper understanding.

Language: Английский

---

Production of Plant Secondary Metabolites: Examples, Tips and Suggestions for Biotechnologists

Genes, Journal Year: 2018, Volume and Issue: 9(6), P. 309 - 309

Published: June 20, 2018

Plants are sessile organisms and, in order to defend themselves against exogenous (a)biotic constraints, they synthesize an array of secondary metabolites which have important physiological and ecological effects. Plant can be classified into four major classes: terpenoids, phenolic compounds, alkaloids sulphur-containing compounds. These phytochemicals antimicrobial, act as attractants/repellents, or deterrents herbivores. The synthesis such a rich variety is also observed undifferentiated plant cells under laboratory conditions further induced with elicitors by feeding precursors. In this review, we discuss the recent literature on production representatives three metabolite artemisinin (a sesquiterpene), lignans (phenolic compounds) caffeine (an alkaloid). Their respective well-known plants, i.e., Artemisia, Coffea arabica L., well neglected species, like fibre-producing Urtica dioica will surveyed. heterologous hosts discussed. Additionally, metabolic engineering strategies increase bioactivity stability surveyed, focusing glycosyltransferases (GTs). We end our review proposing enhance cell cultures inducing wall modifications chemicals/drugs, altered concentrations micronutrient boron quasi-essential element silicon.

Language: Английский

---

Disentangling metabolic functions of bacteria in the honey bee gut

PLoS Biology, Journal Year: 2017, Volume and Issue: 15(12), P. e2003467 - e2003467

Published: Dec. 12, 2017

It is presently unclear how much individual community members contribute to the overall metabolic output of a gut microbiota. To address this question, we used honey bee, which harbors relatively simple and remarkably conserved microbiota with striking parallels mammalian system importance for bee health. Using untargeted metabolomics, profiled changes in gnotobiotic bees that were colonized complete reconstituted from cultured strains. We then determined contribution mono-colonized recapitulated our findings using vitro cultures. Our results show utilizes wide range pollen-derived substrates, including flavonoids outer pollen wall components, suggesting key role degradation recalcitrant secondary plant metabolites digestion. In turn, multiple species responsible accumulation organic acids aromatic compound intermediates. Moreover, specific symbiont, Bifidobacterium asteroides, stimulated production host hormones known impact development. While found evidence cross-feeding interactions, approximately 80% identified also observed bees, Lactobacilli being largest share output. These that, despite prolonged evolutionary associations, bacteria can independently establish metabolize compounds gut. study reveals diverse bacterial functions are likely health provide fundamental insights into activities partitioned within communities.

Language: Английский

---

The cell biology of secondary cell wall biosynthesis

Annals of Botany, Journal Year: 2018, Volume and Issue: 121(6), P. 1107 - 1125

Published: Jan. 12, 2018

Secondary cell walls (SCWs) form the architecture of terrestrial plant biomass. They reinforce tracheary elements and strengthen fibres to permit upright growth formation forest canopies. The cells that synthesize a strong, thick SCW around their protoplast must undergo dramatic commitment cellulose, hemicellulose lignin production.This review puts biosynthesis in cellular context, with aim integrating molecular biology biochemistry biology. While SCWs are deposited diverse tissue contexts including sclerenchyma (fibres sclereids), phloem (fibres) xylem (tracheids, vessels), focus this reflects fact protoxylem have proven be most amenable experimental system which study SCWs.SCW requires co-ordination plasma membrane cellulose synthases, production Golgi polymer deposition apoplast. At where is under guidance cortical microtubules, there high density synthase complexes producing microfibrils consisting 18-24 glucan chains. These extruded into wall matrix rich SCW-specific hemicelluloses, typically xylan mannan. eudicot glucuronoxylan taken as an example illustrate emerging importance protein-protein Golgi. From trans-Golgi, trafficking vesicles carrying synthases oxidative enzymes crucial for exocytosis components at microtubule-rich domains, characteristic patterns. final step lignification, monolignols secreted by lignifying and, some cases, neighbouring well. Oxidative such laccases peroxidases, embedded polysaccharide matrix, determine deposited.

Language: Английский

---

UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice

Nature Communications, Journal Year: 2020, Volume and Issue: 11(1)

Published: May 26, 2020

Abstract Grain size is an important component trait of grain yield, which frequently threatened by abiotic stress. However, little known about how yield and stress tolerance are regulated. Here, we characterize GSA1 , a quantitative locus (QTL) regulating associated with metabolic flux redirection. encodes UDP-glucosyltransferase, exhibits glucosyltransferase activity toward flavonoids monolignols. regulates modulating cell proliferation expansion, regulated flavonoid-mediated auxin levels related gene expression. required for the redirection from lignin biosynthesis to flavonoid under accumulation glycosides, protect rice against overexpression results in larger grains enhanced tolerance. Our findings provide insights into regulation potential means improve crops.

Language: Английский

---