Natural Products Biosynthesis by Streptomyces netropsis IMV Ac-5025 under Exogenous Sterol Action

Antibiotics, Journal Year: 2024, Volume and Issue: 13(2), P. 146 - 146

Published: Feb. 1, 2024

Streptomycetes are known as producers of bioactive substances, particularly antibiotics.

Language: Английский

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Genomic and Phenotypic Characterization of Streptomyces sirii sp. nov., Amicetin-Producing Actinobacteria Isolated from Bamboo Rhizospheric Soil

Microorganisms, Journal Year: 2024, Volume and Issue: 12(12), P. 2628 - 2628

Published: Dec. 19, 2024

In our large-scale search for antimicrobial-producing bacteria, we isolated an actinomycete strain from rhizospheric soil of Bambusa vulgaris. The designated BP-8 showed noticeable antibacterial activity. was subjected to a whole-genome analysis via polyphasic taxonomy approach, and its metabolite identified by HRLS-MS. results the physiological morphological analyses indicated that is aerobic, neutrophilic, mesophilic organism tolerant 8% NaCl can use wide range carbohydrates. It forms curly sporophores with warty surface. phylogenetic average nucleotide identity in silico DNA–DNA hybridization calculation represents type novel Streptomyces species. A comparative genome sequences closest related strains revealed presence genes encoding chemotaxonomic markers characteristic Streptomyces. compound as amicetin. Genomic mining also more than 10 biosynthetic gene clusters have not been described previously may lead discovery new valuable compounds. On basis these results, BP-8T (=VKM Ac-3066T = CCTCC AA 2024094T) proposed species sirii sp. nov.

Language: Английский

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Identification and Application of Streptomyces rapamycinicus CQUSh011 against Potato Late Blight

Journal of Agricultural and Food Chemistry, Journal Year: 2024, Volume and Issue: 72(46), P. 25661 - 25674

Published: Nov. 8, 2024

Using chemical fungicides is the main strategy for controlling potato late blight (PLB), a devastating pre- and postharvest disease caused by

Language: Английский

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Multi-omic investigation identifies key antifungal biochemistry during fermentation of a Streptomyces biological control agent

Microbiological Research, Journal Year: 2024, Volume and Issue: 292, P. 128032 - 128032

Published: Dec. 18, 2024

Language: Английский

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STUDY ON THE ANTAGONISTIC ACTIVITY AGAINST TWO PATHOGENIC BACTERIA IN HUMANS OF STREPTOMYCES MIP_L26 ISOLATED FROM SOIL IN THE ROOT ZONE OF THE MAY CHANG TREE (LITSEA CUBEB)

Tạp chí Y học Quân sự, Journal Year: 2024, Volume and Issue: unknown, P. 6 - 6

Published: Feb. 28, 2024

Purpose: Study on the antagonistic activity against two pathogenic bacteria in humans (Staphylococcus aureus and Streptococcus pneumoniae) of Streptomyces MIP_L26 (Called MIP_L26), isolated from soil root zone May Chang tree; to investigate biological characteristics Subjects methods: Experimental study, determine antimicrobial pneumoniae), some MIP_L26. Results: was identified as having a strong ability causing Staphylococcus pneumoniae with an antibacterial ring diameter 18 ± 5 mm 13 mm, respectively. Based classification according morphological, physiological, biochemical characteristics, combined results 16S rRNA gene sequencing, gancidicus The fermentation medium for biosynthesis substances ISP6 recovery time after 72 hours fermentation.

Language: Английский

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Oligomycin-producing Streptomyces sp. newly isolated from Swiss soils efficiently protect Arabidopsis thaliana against Botrytis cinerea

mSphere, Journal Year: 2024, Volume and Issue: 9(7)

Published: June 12, 2024

is a necrotrophic phytopathogen able to attack more than 200 different plant species causing strong yield losses worldwide. Many synthetic fungicides have been developed control this disease, resulting in the rise of fungicide-resistance

Language: Английский

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Bioactive Streptomycetes: A Powerful Tool to Synthesize Diverse Nanoparticles With Multifarious Properties

Journal of Basic Microbiology, Journal Year: 2024, Volume and Issue: 64(9)

Published: June 23, 2024

ABSTRACT Nanobiotechnology has gained significant attention due to its capacity generate substantial benefits through the integration of microbial biotechnology and nanotechnology. Among organisms, Actinomycetes, particularly prominent genus Streptomycetes, have garnered for their prolific production antibiotics. Streptomycetes emerged as pivotal contributors discovery a number antibiotics play dominant role in combating infectious diseases on global scale. Despite noteworthy progress achieved development utilization combat pathogens, prevalence remains cause mortality worldwide, among elderly children. The emergence antibiotic resistance pathogens diminished efficacy recent decades. Nevertheless, continue demonstrate potential by producing bioactive metabolites synthesis nanoparticles. are instrumental nanoparticles with diverse characteristics, including antiviral, antibacterial, antifungal, antioxidant, antitumor properties. Biologically synthesized exhibited meaningful reduction impact resistance, providing resources new effective drugs. This review succinctly outlines applications crucial element nanoparticle synthesis, showcasing enhanced beneficial applications.

Language: Английский

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In vitro assessment of the nematicidal potential of Streptomyces violascens strain AS2 against root-knot nematodes (Meloidogyne sp.)

Archives of Biological Sciences, Journal Year: 2024, Volume and Issue: 76(3), P. 345 - 358

Published: Jan. 1, 2024

Root-knot nematodes (RKNs, Meloidogyne spp.) present a major challenge to sustainable production. The detrimental environmental impacts and increasing resistance associated with synthetic nematicides have increased the need for biocontrol alternatives. Here, we report first time nematicidal properties of Streptomyces violascens its viability as safe effective solution against nematode infestation. In vitro assays showed that aqueous ethyl acetate extracts S. significantly impeded sp?s reproductive locomotive functions. extract displayed remarkable efficacy, completely inhibiting egg hatching at concentration 600 ?g/mL, an LC50 168.38 causing 99% immobility second-stage juveniles (J2s) 800 ?g/mL within 72 h. Conversely, organic exhibited 29.3% rate (LC50 849.26 ?g/mL) 79% J2s under comparable conditions. These findings point robust potential extracts. Enzymatic profiles supported these results, selected isolate producing chitinase protease enzymes capable degrading eggshells. Our results show strain can be integrated into management practice important agent RKN biocontrol.

Language: Английский

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Inoculation of Bacillus velezensis Bv-116 and its bio-organic fertilizer serve as an environmental friendly biocontrol strategy against cucumber Fusarium wilt

Frontiers in Plant Science, Journal Year: 2024, Volume and Issue: 15

Published: Oct. 15, 2024

The aim of this study was to evaluate the effects Bacillus velezensis Bv-116 and its bio-organic fertilizer on control cucumber Fusarium wilt caused by oxysporum f. sp. Cucumerinum (FOC), promotion growth seedlings, soil microbial community. B. exhibited an inhibition rate 84.93% against FOC, as well broad-spectrum inhibitory activities other soil-borne plant pathogenic fungi. Fermentation products destroyed cell structure FOC inhibited mycelium. These were identified volatile antimicrobial gases, proteases cellulases. In greenhouse pot experiment, both significant promoting growth, a reduction in incidence disease severity index ( p < 0.05). Analysis community rhizosphere revealed that inoculation increased abundance genera with biocontrol capabilities pathogens. addition, reversed excessive proliferation Acidobacteria. Our results suggest potential inoculating environmentally friendly strategy wilt.

Language: Английский

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Purification and characterization of a protease produced by submerged fermentation: Ultrasound-enhanced collagenolytic protease from Streptomyces parvulus

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 137749 - 137749

Published: Nov. 1, 2024

Language: Английский

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