
Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)
Published: Dec. 2, 2024
Fusarium oxysporum is a destructive plant pathogen with robust survival mechanisms, complicating control efforts. This study aimed to develop nanoformulated fungicides, screen antagonistic bacteria, and evaluate their combined efficacy. A novel self-emulsifying nanoemulsion (DZW) was formulated using zein benzaldehyde-modified wheat gluten (BgWG) as carriers for dimethachlon (DTN). The preparation process optimized material ratios emulsification techniques. Concurrently, bacterial strains against F. were screened via the plate standoff method, identifying Bacillus velezensis MLY71 both compatible DTN. DZW achieved particle size of 93.22 nm, an encapsulation efficiency (EE) 90.57%, DTN loading capacity (LC) 67.09%, sustained release over 96 h. combination (0.04 mg·mL⁻¹) B. (1 × 10⁴ CFU·mL⁻¹) 76.66% inhibition rate MLY127, 1.71 times greater than alone, indicating significant synergy. At concentration 0.20 mg·mL⁻¹, showed synergy coefficient 1.33. also observed in soil environments, its adaptability controlling soil-borne pathogens. As sustainable management continues gain attention agricultural disease control, this offers promising strategy achieving higher efficacy same fungicide dose or satisfactory reduced application. excellent drug-loading performance BgWG expanded applications by-product gluten.
Language: Английский