Recent Uses of Spectroscopy in Characterization of Novel Molecules DOI

Aman Sahu,

Nidhi Chadha,

Akansha Agrwal

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 189 - 220

Published: Feb. 14, 2025

Spectroscopy is a vital tool for characterizing novel molecules across various scientific fields, including organic chemistry, material science, biochemistry, pharmacology, environmental astrochemistry, and nanotechnology. In synthesis, techniques like Nuclear Magnetic Resonance (NMR), mass spectrometry, Infrared (IR) spectroscopy are used to determine the structure of newly synthesized compounds. UV-Visible Raman help analyze chemical composition molecular properties in materials. For biomolecules pharmaceuticals, UV-Vis rotational aid studying absorption, emission, interactions. spectroscopic methods microwave, infrared, radio identify space. At nanoscale, Surface-enhanced (SERS) Scanning Tunneling Microscopy (STM) employed. This chapter focuses on electronic, vibrational, rotational, mass, terahertz time domain (THz-TDS) spectroscopy, highlighting their crucial roles characterization.

Language: Английский

Fluroxypyr Inhibits Maize Growth by Disturbing the Diversity of the Endophytic Bacterial Communities in Maize Roots DOI Creative Commons

Gangrui Zhang,

Nan Liu, Shengbo Shi

et al.

Microorganisms, Journal Year: 2025, Volume and Issue: 13(4), P. 728 - 728

Published: March 24, 2025

Fluroxypyr (4-amino-3,5-dichloro-6-fluoro-2-pyridyloxyacetic acid) is a widely used herbicide sprayed on crops worldwide. The effects of fluroxypyr maize growth and the soil microbial community structure have not been reported. In this study, impacts bacterial in endophytes rhizospheric/non-rhizospheric soils were evaluated. We found that structures non-rhizospheric rhizospheric similar. alpha diversity showed richness endophytic communities mature roots was reduced after application. No statistically significant differences observed between fluroxypyr-treated control either or soils. However, composition suggested led to 59.1% reduction abundance Acinetobacter 75.6% Agrobacterium, both which are considered growth-promoting bacteria. addition, we negative effect growth, including decreased ear length root size 100-grain weight. summary, our study suggests may negatively impact by reducing Bacillus kineticus Agrobacterium tumefaciens system.

Language: Английский

Citations

0
Sustainability Challenges in Spectroscopy for Drug Discovery DOI
Chandra Shekhar Sharma,

Mansi Sharma,

Nirmala Kumari

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 401 - 428

Published: Feb. 14, 2025

Sustainability, as defined by the Brundtland Commission, emphasizes development that meets present needs without compromising future generations. Spectroscopy plays a critical role in drug discovery characterizing molecular structures, interactions, and dynamics. However, its sustainability is challenged high energy consumption, resource-intensive manufacturing, hazardous waste disposal, reliance on rare earth elements. To address these concerns, collaborative efforts are needed to develop greener technologies, improve efficiency, promote recycling. Advancements spectroscopic techniques, such ssNMR, LC-UV HRMS, have enhanced efficiency sustainability. Innovations like tandem mass spectrometry, SERS, AI-enabled systems, attenuated total reflectance (ATR) infrared spectroscopy further accuracy while reducing environmental impact. Techniques HPLC, HPTLC, AAS, XRD etc. continue advance fields pharmaceutical analysis, contributing research development.

Language: Английский

Citations

0
Spectroscopy DOI
Pallavi Bhatt, Pawan Kumar Pant, D.P. Sharma

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 357 - 400

Published: Feb. 14, 2025

Spectroscopy has unfolded various strategies for analysing soil fertility and monitoring health, allowing efficient, non-destructive, techniques that are economical to assess properties. A great accuracy in measuring essential parameters, including organic matter, nutrient levels, pH, mineral content can be achieved through the such as near-infrared (Vis-NIR), mid-infrared (MIR), visible X-ray fluorescence (XRF) spectroscopy. These technological approaches assist optimize balance fertilization, augment agricultural productivity reduce environmental impact. The advance studies data science machine learning have upgraded precision relevance of these techniques, resulting adoption it diverse types. This piece work mainly cornerstones fundamentals significance spectroscopic studies, emphasizing their ability enhance sustainable management upgrade by beneficiating a diversified analysis fertility.

Language: Английский

Citations

0
Advancements of UV-Vis Spectroscopy in Drug Discovery DOI

Rashmi Rashmi,

A. Sagar,

Vijay Kumar Juyal

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 97 - 132

Published: Feb. 14, 2025

UV-Vis spectroscopy is a crucial and advanced analytical tool in the pharmaceutical industry, analyzing compounds by measuring light absorption 200-400 nm range. Recent advancements have improved its sensitivity, precision, speed, aiding rapid drug screening real-time monitoring. It assesses identity, strength, purity of compounds, as well raw materials, intermediates. also for evaluating stability, solubility, bioavailability, enhancing development regulatory compliance. Overall, plays pivotal role refining lead ensuring quality control, adhering to standards, solidifying importance industry.

Language: Английский

Citations

0
Revolutionizing Drug Discovery DOI
H. C. Joshi, Prabha Pant, Harsh Kumar Chauhan

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 171 - 188

Published: Feb. 14, 2025

Mass spectrometry (MS) has revolutionized drug discovery, offering unparalleled accuracy in identifying and quantifying biomolecules. Recent advancements, such as high-resolution MS, have enhanced sensitivity resolution, enabling precise molecular characterization. Techniques like liquid chromatography-MS (LC-MS) quantitative including multiple reaction monitoring (MRM), improved metabolism pharmacokinetics studies. Imaging mass (IMS) allows for the spatial visualization of distribution tissues, providing insights into efficacy safety. These innovations accelerate identification candidates their mechanisms, transforming pharmaceutical research personalized medicine development.

Language: Английский

Citations

0
Recent Uses of Spectroscopy in Characterization of Novel Molecules DOI

Aman Sahu,

Nidhi Chadha,

Akansha Agrwal

et al.

Advances in chemical and materials engineering book series, Journal Year: 2025, Volume and Issue: unknown, P. 189 - 220

Published: Feb. 14, 2025

Spectroscopy is a vital tool for characterizing novel molecules across various scientific fields, including organic chemistry, material science, biochemistry, pharmacology, environmental astrochemistry, and nanotechnology. In synthesis, techniques like Nuclear Magnetic Resonance (NMR), mass spectrometry, Infrared (IR) spectroscopy are used to determine the structure of newly synthesized compounds. UV-Visible Raman help analyze chemical composition molecular properties in materials. For biomolecules pharmaceuticals, UV-Vis rotational aid studying absorption, emission, interactions. spectroscopic methods microwave, infrared, radio identify space. At nanoscale, Surface-enhanced (SERS) Scanning Tunneling Microscopy (STM) employed. This chapter focuses on electronic, vibrational, rotational, mass, terahertz time domain (THz-TDS) spectroscopy, highlighting their crucial roles characterization.

Language: Английский

Citations

0