Green Extraction Strategies and Bioactivity of Rheum cordatum Losinsk: Antioxidant, Antimicrobial, and Molecular Docking Insights
Plants,
Journal Year:
2025,
Volume and Issue:
14(7), P. 1071 - 1071
Published: April 1, 2025
This
study
aimed
to
compare
the
efficiency
of
different
green
extraction
methods
for
obtaining
bioactive
compounds
from
roots
Rheum
cordatum
Losinsk
and
evaluate
their
antioxidant
antimicrobial
properties.
The
presence
some
important
phytochemicals
in
extracts
obtained
using
ultrasound-assisted
(UAE),
subcritical
ethanol
(Sbc-EtOH),
supercritical
CO2
(ScCO2)
was
determined
by
LC-MS/MS,
properties
were
examined
against
Staphylococcus
aureus,
Enterococcus
faecalis,
Pseudomonas
aeruginosa,
Escherichia
coli.
goal
determine
optimal
conditions
that
maximize
yield
while
preserving
biological
Different
pressures
(100
bar
400
bar)
tested
UAE
extraction,
solvents
times
Sbc-EtOH
ScCO2
extraction.
Most
53
phenolic
have
been
extracted
method,
either
exclusively
or
highest
amounts.
It
has
observed
more
higher
amounts
at
lower
pressure.
activity
exhibited
extracts.
Additionally,
ScCO2-100
extract
100
showed
strong
activity,
with
a
minimum
inhibitory
concentration
(MIC)
ranging
31.25
250
μg/mL.
Gallic
acid,
epicatechin
gallate,
epigallocatechin
catechin
found
molecular
docking
studies
1QWZ,
2ANQ,
3H77,
6QXS
proteins
revealed
scores
-6.127,
-9.479,
-5.836,
-7.067
kcal/mol,
respectively.
Language: Английский
Boron Compounds as Key Drivers of Innovation: Exploring Their Role in Environmental Remediation, Sustainable Agriculture, Advanced Biomedical Applications, and Green Chemistry
Journal of Organometallic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown, P. 123688 - 123688
Published: April 1, 2025
Language: Английский
Production and Characterization of Plant Extract‐Based Cell‐Friendly and High Mechanical Strength Nanofiber Wound Dressings by Electrospinning Technique
Biopolymers,
Journal Year:
2025,
Volume and Issue:
116(3)
Published: April 30, 2025
ABSTRACT
This
study
focused
on
the
development
of
wound
dressings.
Plant
active
ingredients
such
as
clover,
chickweed,
chamomile,
garlic,
liverwort,
bitter
melon,
pine
resin,
marigold
(
Calendula
officinalis
),
and
St.
John's
Wort
Hypericum
perforatum
L.)
were
reinforced
with
polyethylene
oxide
(PEO)
polyvinyl
alcohol
(PVA)
polymers,
nanofiber
membranes
produced
by
electrospinning.
As
a
result
analyses,
FTIR
confirmed
presence
polymer
ingredient
functional
groups
in
composite
membranes;
softening
shifting
observed
peaks.
In
FEGSEM
analysis,
thin
regular
structure
was
obtained
S12
membrane
range
150–500
nm.
tensile
test,
strength
sample
measured
25.89
MPa,
this
associated
homogeneous
distribution
thinning
fibers.
mesenchymal
stem
cell
viability
determined
98%,
death
2%
for
at
end
72
h.
The
results
show
that
can
be
used
biomaterial
ideal
properties
healing
applications.
Language: Английский