Global, regional and national burden, incidence, and mortality of cervical cancer

Cancer Reports, Journal Year: 2022, Volume and Issue: 6(3)

Published: Dec. 21, 2022

Abstract Aim Among gynecological cancers, cervical cancer is the most common cause of cancer‐related death in developing countries. This study analyzes incidence, mortality, and burden using Global Burden Disease (GBD) 2019 study. Materials Methods The GBD (2019) data on was extracted from Health Data Exchange (GHDx) query tool. Age‐standardized rate (ASR) deaths, lost years life (YLLs), with disabilities (YLDs), adjusted (DALYs) women were extracted. globally for 204 countries groups based a socio‐demographic index (SDI), World Organization (WHO) regions, continents, Bank 22 regions. Results higher standardized age incidence lower SDI countries, Africa, African region (According to WHO), Sub‐Saharan Africa regions). highest deaths ASR low SDI, low‐income group, Organization), According classification, DALYs Low‐income then American region, Latin America & Caribbean‐WB (Based Conclusion In 2019, mostly affected socioeconomic status. Given that highly preventable, access screening services presence trained knowledgeable health care staff can reduce illness, suffering, caused by this malignancy. It recommended use national international potentials

Language: Английский

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An umbrella review of systematic reviews on the impact of the COVID-19 pandemic on cancer prevention and management, and patient needs

eLife, Journal Year: 2023, Volume and Issue: 12

Published: April 4, 2023

The relocation and reconstruction of health care resources systems during the coronavirus disease 2019 (COVID-19) pandemic may have affected cancer care. An umbrella review was undertaken to summarize findings from systematic reviews on impact COVID-19 treatment modification, delays, cancellations; delays or cancellations in screening diagnosis; psychosocial well-being, financial distress, use telemedicine as well other aspects Bibliographic databases were searched for relevant with without meta-analysis published before November 29th, 2022. Abstract, full- text screening, data extraction performed by two independent reviewers. AMSTAR-2 used critical appraisal included reviews. Fifty-one our analysis. Most based observational studies judged be at medium high risk bias. Only had moderate scores AMSTAR-2. Findings suggest modifications versus pre-pandemic period low level evidence. Different degrees treatment, diagnosis observed, low- and- middle- income countries that implemented lockdowns being disproportionally affected. A shift in-person appointments but utility telemedicine, challenges implementation cost-effectiveness little explored. Evidence consistent suggesting well-being patients deteriorated, experienced albeit results general not compared levels. Impact disruption prognosis In conclusion, substantial heterogenous has been observed.

Language: Английский

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Learning through a Pandemic: The Current State of Knowledge on COVID-19 and Cancer

Cancer Discovery, Journal Year: 2021, Volume and Issue: 12(2), P. 303 - 330

Published: Dec. 10, 2021

The ongoing coronavirus disease 2019 (COVID-19) pandemic has left patients with current or past history of cancer facing disparate consequences at every stage the trajectory. This comprehensive review offers a landscape analysis state literature on COVID-19 and cancer, including immune response to COVID-19, risk factors for severe disease, impact anticancer therapies. We also latest data treatment vaccination safety efficacy in as well care, urgent need rapid evidence generation real-world study designs. SIGNIFICANCE: Patients have faced journey due pandemic. field regarding cancer. cover response, implications care delivery. Overall, this provides an in-depth summary key issues during unprecedented health crisis.

Language: Английский

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“I want to get myself as fit as I can and not die just yet” – Perceptions of exercise in people with advanced cancer and cachexia: a qualitative study

BMC Palliative Care, Journal Year: 2022, Volume and Issue: 21(1)

Published: May 17, 2022

Cachexia is a prevalent muscle wasting syndrome among people with advanced cancer that profoundly impacts patient quality of life (QoL) and physical function. Exercise can improve QoL, function, overall health in may be an important addition to treatment approaches for cachexia. Greater understanding patients' perception exercise help elucidate the feasibility implementing interventions cachexia facilitate design patient-centered interventions. We aimed describe patients cachexia, capture motivators, barriers, preferences, inform Individual interviews (n = 20) locally or metastatic were conducted analyzed using reflexive thematic analysis. Main themes from were: 1) Life disrupted by cachexia; 2) offers hope; 3) barriers are multifaceted; 4) access support important. Participants reported their had intensely altered lives, including ability exercise. was perceived as participants described hope wellbeing. Yet, several complex such burdensome symptoms overwhelming impact COVID-19 pandemic, hindered participation prevented fully realizing benefits Factors believed engagement overcome included increased (e.g., professional supervision) accessibility convenient locations). Patient-reported preferences interventions, particularly within future research studies aiming establish efficacy

Language: Английский

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Mental Health and Quality of Life among Patients with Cancer during the SARS-CoV-2 Pandemic: Results from the Longitudinal ONCOVID Survey Study

Cancers, Journal Year: 2022, Volume and Issue: 14(4), P. 1093 - 1093

Published: Feb. 21, 2022

Purpose: This longitudinal survey study aimed to investigate the self-reported outcome measures of COVID-19 peritraumatic distress, depression, anxiety, stress, quality life (QOL), and their associated factors in a cohort cancer patients treated at tertiary care hospital during SARS-CoV-2 pandemic. Methods: Surveys were administered four time points between 1 April 2020 18 September 2020. The surveys included CPDI, DASS-21, WHOQOL-BREF questionnaires. Results: Survey response rates high (61.0% 79.1%). Among 355 participants, 71.3% female, median age was 62.2 years (IQR, 53.9 69.1). majority (78.6%) with palliative intention. An important proportion participants reported symptoms distress (34.2% 39.6%), depression (27.6% 33.5%), anxiety (24.9% 32.7%), stress (11.4% 15.7%) any point period. We did not find clinically meaningful mental health QOL differences period, remarkably little change pandemic’s first second wave. found no consistent correlates or scores, including type, therapy intention, sociodemographic information. Conclusion: showed considerable resilience against deterioration

Language: Английский

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Impact of the Sars-Cov-2 outbreak on the initial clinical presentation of new solid cancer diagnoses: a systematic review and meta-analysis

BMC Cancer, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 29, 2024

Abstract Background The COVID-19 pandemic might have delayed cancer diagnosis and management. aim of this systematic review was to compare the initial tumor stage new diagnoses before after pandemic. Methods We systematically reviewed articles that compared solid waves. conducted a random-effects meta-analysis rate metastatic tumors distribution stages at diagnosis. Subgroup analyses were performed by primary site country. Results From 2,013 studies published between January 2020 April 2022, we included 58 with 109,996 patients. higher outbreak than (pooled OR: 1.29 (95% CI, 1.06-1.57), I 2 : 89% 86-91)). For specific cancers, common ORs reached statistical significance for breast (OR: 1.51 CI 1.07-2.12)) gynecologic 1.04-2.18)) but not other types. According countries, OR CI) only Italy: 1.55 (1.01-2.39) Spain:1.14 (1.02-1.29). Rates comparable I-II versus III-IV in which information available, III did include Conclusions Despite inter-study heterogeneity, our showed burden social distancing policies explain those results, as patients may seeking care.

Language: Английский

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The influence of social interactions in mitigating psychological distress during the COVID−19 pandemic: a study in Sri Lanka

Frontiers in Psychology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 6, 2025

Massive changes in many aspects related to social groups of different socioeconomic backgrounds were caused by the COVID-19 pandemic and as a result, overall state mental health was severely affected globally. This study examined how Sri Lankan citizens representing range terms their health. The data used this research gathered from 3,020 households using nationwide face-to-face survey, which processed dataset 921 responses considered for final analysis. Four distinct factors identified factor analysis (FA) that conducted subsequently, population clustered unsupervised clustering determine subgroups similarly. Two such where respective relationships retrieved principal demographics thoroughly interpreted. resulted identification contrasting perspectives between two toward maintenance during pandemic, revealed one group more "socially connected" nature resulting being comparatively better coping with pandemic. other seen be reserved" showing an opposite reaction connections while well-being declined symptoms loneliness, emptiness response role media, it observed media perceived substitute lack or primarily mechanism challenges results show maintaining physically via online rather than use has helped over decreasing emptiness, loneliness fear death.

Language: Английский

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The Lived Experience of Suffering by Nigerian Female Breast Cancer Survivors: A Phenomenological Perspective

Journal of Patient Experience, Journal Year: 2025, Volume and Issue: 12

Published: Jan. 1, 2025

Breast cancer is a significant public health concern globally, and its impact extends beyond physical survival. Survivors often grapple with myriad of challenges, including psychological distress, social isolation, financial hardship. These challenges are exacerbated in low-resource settings like Nigeria, where limited access to quality healthcare, socioeconomic disparities, cultural stigma surrounding can significantly the life for survivors. This study aims explore suffering perceived by long-term breast survivors focusing on their lived experiences during after treatment. Using phenomenological approach, in-depth interviews were conducted 22 women who have survived over 5 years. Data analyzed using thematic analysis capture essence suffering, allowing deep understanding experiences. Five main domains emerged: (1) Physical Suffering, (2) Emotional Distress, (3) Social (4) Financial Strain, (5) Spiritual Resilient Coping. Participants described as multifaceted journey marked pain, emotional turmoil, stigma, resilience fostered through spirituality support systems. The revealed that participants' extended physical, touching every aspect lives reshaping identities perceptions self. findings highlight complex nature among underscoring need comprehensive survivorship care addresses psychosocial, spiritual dimensions. By healthcare providers develop more compassionate, context-specific strategies validate holistic needs

Language: Английский

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Exploring the impact of the COVID-19 pandemic on cancer-related distress among thoracic oncology patients at a rural cancer center

Supportive Care in Cancer, Journal Year: 2025, Volume and Issue: 33(2)

Published: Feb. 1, 2025

Language: Английский

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SARS‐CoV‐2 Infection Aggravates Physical and Mental Health in Cancer Patients Compared to Co‐Living Individuals

Cancer Medicine, Journal Year: 2025, Volume and Issue: 14(6)

Published: March 1, 2025

Cancer patients are particularly vulnerable to the psychological sequels of COVID-19 due their immunocompromised state and disruptions regular oncological care. There is limited research comparing effects SARS-CoV-2 on cancer co-living individuals. This study aims explore similarities differences in physical outcomes between these two groups, with a 1-year follow-up assess long-term effects. retrospective observational was conducted January February 2023. A total 107 participants were included: 72 35 individuals, all diagnosed COVID-19. Clinical laboratory data collected. Depression, anxiety, fatigue assessed at timepoints: shortly after diagnosis 1 year later. exhibited higher rates gastrointestinal symptoms, such as diarrhea (20.83% vs. 5.71%, p = 0.045), which associated increased anxiety depression (p < 0.05). Advanced-stage 0.01) lack vaccination correlated worse outcomes. Female reported scores Laboratory findings indicated neutrophil percentages 0.001), fibrinogen D-dimer levels 0.015) patients, signaling risk inflammation thrombosis. Both groups showed improvements over follow-up, but continued report greater distress 0.001) 0.024). infected experienced more severe symptoms compared persistent infection. ChiCTR2300067577.

Language: Английский

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