A review of the literature on wellbeing and modifiable dementia risk factors

Ageing Research Reviews, Journal Year: 2024, Volume and Issue: 99, P. 102380 - 102380

Published: June 15, 2024

Wellbeing—defined broadly as experiencing one's life enjoyable and fulfilling—has been associated with lower risk for Alzheimer's disease related dementias. The mechanisms underlying this association are largely unknown. However, prior research theory suggest that wellbeing impacts health behaviors biological systems relevant to cognitive brain health. Several of these factors have also identified by the 2020 Lancet Commission on Dementia Prevention, Intervention, Care modifiable dementia factors. In current review, we summarize evaluate evidence associations between each 12 We found relatively consistent higher levels most factors: physical inactivity, social isolation, smoking, depression, hypertension, diabetes, hearing loss, traumatic injury, air pollution. By contrast, only modest education mixed alcohol use body weight. Although reviewed was observational, longitudinal experimental suggests many observed likely bidirectional. These findings may be mediators (i.e., intermediate steps in causal chain) and/or confounders variables impact both dementia, thus could induce a spurious association) dementia. conclude discussing next test mediation hypotheses account potential confounding relation

Language: Английский

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Measuring psychological well-being in a danish pregnancy cohort using the self-reported WHO-5 index

BMC Psychology, Journal Year: 2025, Volume and Issue: 13(1)

Published: Jan. 15, 2025

Reduced well-being and depressive episodes frequently complicate pregnancy can result in serious adverse outcomes for both mother infant if left untreated. This study aimed to assess the psychometric validity of 5-item World Health Organization index (WHO-5), evaluate WHO-5 serve as a proxy two items core symptoms from Major Depression Inventory (MDI), identified MDI-2. Additionally, paper detect risk factors reduced using index. Using index, this analyzed psychological population 37,129 women their first trimester pregnancy. The was evaluated confirmatory factor analysis item response theory. Furthermore, cut-off scores previously associated with mental distress, ≤ 50 28, were terms sensitivity, specificity, positive- negative predictive values compared MDI-2 subsample n = 1001 women. Lower mean score on seen among pregnant 25 years old, lower educational level, who unemployed, nulliparous, did not understand Danish language, cohabitating, smokers, exercise prior found be valid instrument, however, could pooled or across understood Danish. sensitivity specificity predicting presence one symptom 0.81 0.82, respectively, while 28 0.32 0.98, respectively. had high degree acceptability well-known distress population. instrument pregnancy, our indicated low value investigated identification symptoms.

Language: Английский

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Subjective Well-being: A Key to Bridge Urbanization, Brain and Mental Health

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 10, 2025

The pursuit of happiness is a lifelong endeavor for everyone; nevertheless, elucidating its etiology, neurobiological substrates, and implications mental health continues to pose significant challenges in contemporary research. This study sought delineate the causal relationships among subjective well-being (SWB), urbanization, brain, health, explore protective role SWB against prevalent psychiatric disorders. Utilizing data from 198,823 adults UK Biobank, including questionnaires (five items), urban living environments (121 variables), neuroimaging (2,413 measures), assessments (39 indicators), ICD-10 diagnoses (10 disorders), we initially identified two robust components using ten-fold cross-validated factor analysis: internal (ISWB) social (SSWB). Phenome-wide association studies (PheWAS) revealed associations between urbanization variables both ISWB (78/121) SSWB (59/121); indicators (416/2,413 measures) (77/2,413); (38/39 indicators) (37/39) (P < 0.05, Bonferroni corrected). Sequential mediation analysis uncovered 28 pathways brain (ISWB: 16 pathways, SSWB: 12 pathways), while moderated 19 where significantly → (14 ISWB, 5 SSWB). Finally, Cox proportional hazards survival demonstrated that individuals highest sextile had 76% reduction overall risk developing 10 disorders compared with those lowest (Z = -29.49, Hazard Ratio [HR] 0.24, P 3.93e-191), showed 36% -9.42, HR 0.64, 4.50e-2). Moreover, effects depression 0.13, 0.39). By systematically uncovering through which differentially participate regulation on human thereby affecting this thus provides biological evidence modifiable prevention common

Language: Английский

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Personal Well-Being Index (PWI) and its Association with Physical Health, Mental Health and Leisure Activities: Results from the Health and Lifestyle Survey

Journal of Happiness Studies, Journal Year: 2025, Volume and Issue: 26(4)

Published: April 1, 2025

Language: Английский

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Women’s Mental Health During COVID-19 in South Africa

Applied Research in Quality of Life, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 20, 2024

Language: Английский

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Who are the convoys of the happiness of Chinese urban residents? Research on social relations and subjective well-being based on the convoy model

Frontiers in Psychology, Journal Year: 2023, Volume and Issue: 14

Published: Sept. 5, 2023

Introduction While the rapid advancement of urbanization has driven improvement material living standards, it also brought about social changes and intensified competition. In this “involutive” environment characterized by highly competitive strong pressure, urban residents tend to fall into a state “mental exhaustion.” Anxiety, depression, sleep disorders, other mental illnesses have seriously threatened public health in Chinese cities. Support from relations is crucial for enhancing residents’ subjective well-being (SWB) promoting their health, especially China’s contextualized collectivist culture. Methods According structure “difference sequence pattern,” paper constructs theoretical framework relationship between SWB based on convoy model uses CGSS2018 data verify applicability framework. Results Kinship friendship positively relate SWB, interaction effect significantly negative. There no necessary correlation neighborhood SWB. The different age groups heterogeneous. addition, moderating effects relative income class are Discussion convoys, these two factors an obvious substitution effect. withdrawn orbit which may be related indifference caused housing system reform. From life course perspective, convoys young middle-aged consist kinship friendship, while those elderly people include neighborhood. poor individuals at bottom society, support most important source capital. These findings provide new insights welfare residents.

Language: Английский

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Enhancing Subjective Wellbeing in Older Individuals with Amnestic Mild Cognitive Impairment: A Randomized Trial of a Positive Psychology Intervention

Behavioral Sciences, Journal Year: 2023, Volume and Issue: 13(10), P. 838 - 838

Published: Oct. 13, 2023

Objectives: This pilot study aims to explore the potential of a positive psychology intervention (PPI) in enhancing subjective well-being older individuals with amnestic mild cognitive impairment (MCI), precursor dementia. Design and Setting: A randomized trial was conducted, initially recruiting 51 participants aged 65 above from Greek Association Alzheimer’s Disease Related Disorders Thessaloniki, Greece. The employed control-experimental group setup. To ensure randomization, each participant assigned unique number, random number generator used for allocation. Participants: total 41 eligible (MCI) were included after screening. Intervention: consisted 3-week program where PERMA Profiler questionnaire administered at three intervals: pre-intervention, post-intervention, one month completion. Main Outcome Measures: participants. Results: analysis, conducted mainly through mixed-measures ANOVAs, supported study’s hypotheses, revealing that PPI led increased model scores overall well-being, which persisted even month. Conversely, non-participants experienced declines most domains except Positive Emotion Meaning, demonstrated improvement recovery during follow-up. Conclusions: These findings suggest adults MCI, implications addressing dementia-related challenges. Further investigation is warranted pinpoint effects on MCI tailor interventions improved well-being.

Language: Английский

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Lifestyle factors, physical health, and life satisfaction under different changes in depressive symptoms among Chinese community-dwelling older adults: A longitudinal analysis

International Journal of Social Psychiatry, Journal Year: 2024, Volume and Issue: 70(6), P. 1062 - 1074

Published: June 1, 2024

Background: The study aims to investigate the long-term impact of lifestyle-related factors and physical health on life satisfaction depressive symptoms among Chinese community-dwelling older adults. Methods: Using data from China Health Retirement Longitudinal Study (CHARLS), analytic sample this included 1,068 adults who had participated in surveys both 2011 2018. Multivariate regression was employed analyze cross-sectional longitudinal relationships between factors, health, subjective well-being – specifically satisfaction. Additionally, model tested how these correlate with across different groups symptom changes adults, categorized as not at risk depression, intermittent chronic depression. Results: Multimorbidity significantly related baseline follow-up Shorter sleep duration associated depression risk. Current alcohol drinkers reported more severe than non-drinkers. At baseline, current smokers were likely have a lower degree nonsmokers. Among 7-year follow-up, former tended Conclusions: Our findings identified drinking having shorter modifiable for late-life smoking detrimental factor significant predictor symptoms. implications future psychosocial interventions that target alleviation promotion people based their mental conditions.

Language: Английский

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Testing the potential therapeutic effects of an online creative arts-based intervention for people with anxiety

Arts & Health, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 12

Published: June 10, 2024

Background Creative arts-based interventions are a relatively new addition to the toolkit of psychological treatments for mental afflictions. As such, therapeutic efficacy these therapies when conducted remotely via digital media has been under-researched. To address this gap, study tested effects an online creative intervention alleviate anxiety.

Language: Английский

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Mental health on two continua: mental wellbeing and common mental disorders in a community-based cross-sectional study with women in urban informal settlements in India

BMC Women s Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 9, 2024

We considered the suggestion that mental health is product of two intersecting continua: psychological distress and wellbeing.

Language: Английский

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