Factors influencing anxiety and depression in advanced hepatocellular carcinoma patients and their impact on quality of life DOI

Hendi Maher,

Bin Zhang,

Jiemin Lv

et al.

World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(5)

Published: April 30, 2025

BACKGROUND Patients with middle and advanced hepatocellular carcinoma (HCC) frequently experience significant anxiety depression, severely affecting their quality of life. AIM To examine the depression status patients HCC, influencing factors, correlation between these psychological factors METHODS We collected baseline data from 100 assessing levels using Hamilton Anxiety Rating Scale (HAMA) Depression (HAMD). Quality life was evaluated Functional Assessment Cancer Therapy-Hepatobiliary Questionnaire. Multivariate logistic regression analyzed clinical psychosocial while Pearson assessed relationships among HAMA, HAMD, Questionnaire scores. RESULTS Results indicated that 64% exhibited 65% showed symptoms. Key included Barcelona Clinic Liver C stage, multiple tumors, social support, prior treatments (such as liver resection transcatheter arterial chemoembolization/hepatic artery infusion chemotherapy), well HAMA HAMD correlated negatively life, coefficients -0.671 -0.575 for respectively. CONCLUSION are prevalent impacting This underscores need health considerations in cancer treatment establishing interventions is essential.

Language: Английский

Factors influencing anxiety and depression in advanced hepatocellular carcinoma patients and their impact on quality of life DOI

Hendi Maher,

Bin Zhang,

Jiemin Lv

et al.

World Journal of Psychiatry, Journal Year: 2025, Volume and Issue: 15(5)

Published: April 30, 2025

BACKGROUND Patients with middle and advanced hepatocellular carcinoma (HCC) frequently experience significant anxiety depression, severely affecting their quality of life. AIM To examine the depression status patients HCC, influencing factors, correlation between these psychological factors METHODS We collected baseline data from 100 assessing levels using Hamilton Anxiety Rating Scale (HAMA) Depression (HAMD). Quality life was evaluated Functional Assessment Cancer Therapy-Hepatobiliary Questionnaire. Multivariate logistic regression analyzed clinical psychosocial while Pearson assessed relationships among HAMA, HAMD, Questionnaire scores. RESULTS Results indicated that 64% exhibited 65% showed symptoms. Key included Barcelona Clinic Liver C stage, multiple tumors, social support, prior treatments (such as liver resection transcatheter arterial chemoembolization/hepatic artery infusion chemotherapy), well HAMA HAMD correlated negatively life, coefficients -0.671 -0.575 for respectively. CONCLUSION are prevalent impacting This underscores need health considerations in cancer treatment establishing interventions is essential.

Language: Английский

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