Repetitive transcranial magnetic stimulation can improve the fixation of eyes rather than the fixation preference in children with autism spectrum disorder. DOI Creative Commons
Li Tian, Shuai Ma, Yin Li

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: Dec. 28, 2022

Abstract Background Transcranial magnetic stimulation (TMS) has been introduced into the intervention of autism spectrum disorders (ASD) as a possible new therapeutic option for modifying pathological neuroplasticity. However, stimulating protocols rTMS ASD have not approved unanimously, which affects clinical popularization and application rTMS. In addition, there is little research on improvement social processing autistic children by Methods We explored efficacy face with protocol left high-frequency right low-frequency bilateral dorsolateral prefrontal cortex (DLPFC), sample 45 participants aged 2–18. Results Our results showed that both score Childhood Autism Rating Scale (CARS) fixations eyes human faces improved two-session intervention, except eye preference. The mediation analysis indicated item “Adaptation to Change” CARS mediated dominantly eye-gaze behavior Conclusions study revealed mechanism in improving population, deepened understanding function treating disorders, provided reference combined treatment ASD.

Language: Английский

Repetitive transcranial magnetic stimulation for insomnia in patients with autism spectrum disorder: Study protocol for a randomized, double-blind, and sham-controlled clinical trial DOI Creative Commons
Jian Jiao, T. Lu, Ye Zhang

et al.

Frontiers in Psychiatry, Journal Year: 2022, Volume and Issue: 13

Published: Sept. 28, 2022

Insomnia is the most common comorbidity in children with autism spectrum disorder (ASD) and seriously affects their rehabilitation prognosis. Thus, an intervention targeting insomnia ASD seems warranted. Repetitive transcranial magnetic stimulation (rTMS), a potentially effective treatment for improving sleep quality optimizing structure, has already been demonstrated to alleviate symptoms disturbance different neurological neuropsychiatric conditions. This trial aims investigate effects of rTMS on patients ASD. study designed be double-blind, randomized, sham-controlled target sample size 30 participants (aged 3-13 years) diagnosed comorbid insomnia. The phase will comprise 20 sessions or sham applied over right dorsolateral prefrontal cortex (DLPFC) within four consecutive weeks. effect other investigated through home-PSG (two overnights), diary, CSHQ, CARS, ABC, SRS, RBS-R, metabolomics analysis at baseline posttreatment. A follow-up assessment 1 month after examine long-term effects. results this may address important knowledge gap provide evidence use treat Furthermore, it elucidate potential mechanism link between disorders clinical symptoms. ongoing registered Chinese Clinical Trial Registry (ChiCTR2100049266) 28/07/2021.

Language: Английский

Citations

2
Exploring the effects of repetitive transcranial magnetic stimulation on co-morbid sleep disorders in preschool children with ADHD DOI Creative Commons
Yilin Jiang, Zhou Heng, Jiayang Liu

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 27, 2023

Abstract Background Attention Deficit Hyperactivity Disorder(ADHD) is one of the most common neurological developmental disorders in children and sleep (SD) are a co-morbidity with ADHD. There currently no pharmacological treatment options for SD ADHD preschool age (4–6 years). Repetitive transcranial magnetic stimulation (rTMS) novel non-invasive neuromodulation technique. This study explored effectiveness rTMS co-morbid preschool-aged Methods Thirty-five were recruited this study. They met diagnostic criteria Diagnostic Statistical Manual Mental Disorders, Fifth Edition (DSM-5). The divided into parent behaviour management training (PBMT) group (n = 19) repetitive combined 16). Both groups underwent eight weeks PBMT. Children PBMT given right DLPFC low frequency intervention three times week first four weeks. children's levels assessed using Chinese version Children's Sleep Habits Questionnaire (CSHQ), which was measured before start intervention, at end eight-week after used to measure effects both methods. Within-group differences compared one-way ANOVA, between-group an independent samples T-test. Results significantly improved (p < 0.05), but effect more pronounced 0.05) lasted longer than 0.05). Conclusion stimulation(rTMS) promising non-pharmacological therapy improve

Language: Английский

Citations

0
Repetitive transcranial magnetic stimulation can improve the fixation of eyes rather than the fixation preference in children with autism spectrum disorder. DOI Creative Commons
Li Tian, Shuai Ma, Yin Li

et al.

Research Square (Research Square), Journal Year: 2022, Volume and Issue: unknown

Published: Dec. 28, 2022

Abstract Background Transcranial magnetic stimulation (TMS) has been introduced into the intervention of autism spectrum disorders (ASD) as a possible new therapeutic option for modifying pathological neuroplasticity. However, stimulating protocols rTMS ASD have not approved unanimously, which affects clinical popularization and application rTMS. In addition, there is little research on improvement social processing autistic children by Methods We explored efficacy face with protocol left high-frequency right low-frequency bilateral dorsolateral prefrontal cortex (DLPFC), sample 45 participants aged 2–18. Results Our results showed that both score Childhood Autism Rating Scale (CARS) fixations eyes human faces improved two-session intervention, except eye preference. The mediation analysis indicated item “Adaptation to Change” CARS mediated dominantly eye-gaze behavior Conclusions study revealed mechanism in improving population, deepened understanding function treating disorders, provided reference combined treatment ASD.

Language: Английский

Citations

0