Long COVID, the Brain, Nerves, and Cognitive Function

Neurology International, Journal Year: 2023, Volume and Issue: 15(3), P. 821 - 841

Published: July 6, 2023

SARS-CoV-2, a single-stranded RNA coronavirus, causes an illness known as coronavirus disease 2019 (COVID-19). Long-term complications are increasing issue in patients who have been infected with COVID-19 and may be result of viral-associated systemic central nervous system inflammation or arise from virus-induced hypercoagulable state. incite changes brain function wide range lingering symptoms. Patients often experience fatigue note fog, sensorimotor symptoms, sleep disturbances. Prolonged neurological neuropsychiatric symptoms prevalent can interfere substantially everyday life, leading to massive public health concern. The mechanistic pathways by which SARS-CoV-2 infection sequelae important subject ongoing research. Inflammation- induced blood-brain barrier permeability viral neuro-invasion direct nerve damage involved. Though the mechanisms uncertain, resulting documented numerous patient reports studies. This review examines constellation spectrum seen long COVID incorporates information on prevalence these contributing factors, typical course. Although treatment options generally lacking, potential therapeutic approaches for alleviating improving quality life explored.

Language: Английский

---

Effects of the COVID-19 Pandemic on University Students' Mental Health: A Literature Review

Cureus, Journal Year: 2024, Volume and Issue: unknown

Published: Feb. 11, 2024

This review aims to focus on the effects of COVID-19 university students' mental health and deepen our understanding it. The conclusions are based 32 studies conducted during pandemic. confirms that students were at high risk for disorders, heightened stress, increased sleep comorbidities both pre-pandemic literature confirmed a few universal trends, i.e., anxiety, depression, rates insomnia, obsessive-compulsive disorder, suicidal ideation also went up. Overall, female disadvantage in development issues. Male coped better but may be higher lethality ideation. Students with history issues other prior pandemic had worse outcomes compared healthy individuals. study points strong positive correlation between fear insomnia. There is declining online learning. A negative was present physical activity depressive symptoms. These findings across many countries regions where occurred.

Language: Английский

---

Worldwide prevalence of obsessive-compulsive symptoms during the COVID-19 pandemic: A systematic review and meta-analysis

Journal of Psychiatric Research, Journal Year: 2024, Volume and Issue: 172, P. 360 - 381

Published: Feb. 21, 2024

Language: Английский

---

Acceptability, feasibility, and effectiveness of internet-based cognitive behavior therapy for obsessive–compulsive disorder (OCD-NET): a naturalistic pilot trial during the COVID-19 pandemic in a psychiatric outpatient department in Germany

BMC Psychiatry, Journal Year: 2025, Volume and Issue: 25(1)

Published: Jan. 30, 2025

Language: Английский

---

The long-term impact of the covid-19 pandemic on patients with obsessive–compulsive disorder

Medicine, Journal Year: 2025, Volume and Issue: 104(7), P. e41562 - e41562

Published: Feb. 14, 2025

We investigated how patients with obsessive–compulsive disorder (OCD) were affected by coronavirus disease of 2019 (COVID-19)-related stress over the long term compared to healthy individuals. explored pandemic changes in symptoms and their contributing factors. The study included 100 OCD sex-matched controls whose sociodemographic clinical information gathered. Participants recruited between December 2021 May 2022 from individuals attending outpatient clinics University Department Psychiatry. Depression Anxiety Stress Scale-21, Perceptions Attitudes Towards COVID-19 Questionnaire, Compliance Prevention Measures Scale, Scale used this study. Patients assessed using Yale-Brown Obsession Compulsion based on conditions before during pandemic. perceived as more dangerous contagious (respectively P = .01, .01) controls. Fifty percent experienced an increase symptoms. Disease severity was increased mild moderate OCD, while no significant change found severe OCD. Perceiving ( .031), COVID-19-related traumatic .013), compulsive control .022), xenophobia .005), thoughts .008) frequent worsening. In regression analysis, younger age (OR: 0.95, 95% CI (0.91–0.99)) higher levels 1.03 (1.01–1.05)) are associated worsening adversely Close monitoring is recommended.

Language: Английский

---

An Educational Program to Enhance the Identification of Obsessive-Compulsive Disorder and the Utilization of Exposure and Response Prevention Among Outpatient Mental Health Providers

Issues in Mental Health Nursing, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 5

Published: Feb. 19, 2025

Background Obsessive-compulsive disorder (OCD) is a prevalent and impairing psychiatric that frequently misdiagnosed. Further, despite breadth of evidence in support Exposure Response Prevention (ERP) the treatment OCD, it often underutilized or used incorrectly.

Language: Английский

---

Screen Time and Obsessive-Compulsive Disorder Among Children 9–10 Years Old: A Prospective Cohort Study

Journal of Adolescent Health, Journal Year: 2022, Volume and Issue: 72(3), P. 390 - 396

Published: Dec. 12, 2022

The aim of this study is to determine the prospective associations between baseline screen time and obsessive-compulsive disorder (OCD) at 2-year follow-up in a national (United States) cohort 9- 10-year-old children.

Language: Английский

---

PTSD trajectories across different mental disorders in the second year of the COVID-19 pandemic in Italy: a naturalistic, longitudinal, multicenter study

International Review of Psychiatry, Journal Year: 2022, Volume and Issue: 34(7-8), P. 797 - 808

Published: Nov. 17, 2022

The potentially traumatic impact of the COVID-19 pandemic in subjects with pre-existing mental disorders is still unclear, especially regarding its long-term consequences. aim this study was to prospectively assess post-traumatic stress disorder (PTSD) and symptoms (PTSS) patients disorders, during 3rd wave infection (T0, March-April 2021) while strict containment measures were applied Italy, after 3 months (T1, June-July 2021), reduced restrictive measures. A total sample 527 subjects, different DSM-5 diagnoses, consecutively enrolled at nine Italian psychiatric outpatient services. Assessments T0 included: Trauma Loss Spectrum-Self Report (TALS-SR), Impact Event Scale-Revised (IES-R) Work Social Adjustment Scale (WSAS). These two latter repeated T1. Results showed that T0, 43.6% reported PTSD, females (p = .004), younger .011), unemployed/students living their parental families .017), resulting more affected. Differences PTSD rates emerged across diagnostic groups ranging from 10% psychoses up 59% those feeding eating disorders. An improvement T1 all for IES-R scores, WSAS scores improved only mood In conclusions, presented relevant PTSS 1-year into pandemic. Further studies are needed follow-up course burden severe

Language: Английский

---

Age-specific determinants of psychiatric outcomes after the first COVID-19 wave: baseline findings from a Canadian online cohort study

Child and Adolescent Psychiatry and Mental Health, Journal Year: 2023, Volume and Issue: 17(1)

Published: Feb. 6, 2023

Canadians endured unprecedented mental health (MH) and support access challenges during the first COVID-19 wave. Identifying groups of individuals who remain at risk beyond acute pandemic phase is key to guiding systemic intervention efforts policy. We hypothesized that determinants three complementary, clinically actionable psychiatric outcomes would differ across Canadian age groups.The Personal Impacts Survey (PICS) was iteratively developed with stakeholder feedback, incorporating validated, age-appropriate measures. Baseline, cross-sectional online data collected between November 2020-July 2021 used in analyses. Age group-specific were sought for baseline MH outcomes: (1) current probable depression, generalized anxiety disorder, obsessive-compulsive disorder and/or suicide attempt COVID-19, (2) increased severity any lifetime diagnosis, (3) inadequate COVID-19. Multivariable logistic regression models constructed children, youth (self- parent-report), young adults (19-29 years) over 29 years, using survey type as a covariate. Statistical significance defined by 95% confidence interval excluding an odds ratio one.Data from 3140 surveys analyzed. Late adolescence early adulthood identified life phases worst outcomes. Poverty, limited education, home maker/caregiver roles, female non-binary gender, LGBTQ2S + status special educational, medical conditions differentially groups.Negative impacts on include poor clearly persisted wave, widening pre-existing inequity gaps. This should guide policy makers clinicians future prioritization efforts.

Language: Английский

---

Too much of a good thing? Hand hygiene and the long-term course of contamination-related obsessive-compulsive symptoms

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: March 8, 2024

Increased hygiene behavior may be a factor in the development of contamination-related obsessive-compulsive symptoms (C-OCS). We aimed at investigating (1) course C-OCS over 1 year after start COVID-19 pandemic and (2) effects changes hand (i.e., duration frequency handwashing) related distress regulation on long-term C-OCS. In longitudinal study, we assessed 1,220 individuals from German general population (t1), 3 months later (t2), 12 (t3). Pre-pandemic data were available subsample 2014 ( n = 430). A decrease first emerged with small effect size. Thirty-six percent participants scored above clinical cut-off score t1, 31% t2, 27% t3. 2014, only 11% score. Hierarchical regression showed that t1 was strongest predictor increase With sizes, change (not frequency) handwashing to as well distress-reducing served additional predictors. Implications for information guidelines are discussed.

Language: Английский

---