Frontiers in Psychology, Journal Year: 2023, Volume and Issue: 14
Published: Jan. 30, 2023
EDITORIAL article Front. Psychol., 30 January 2023Sec. Psychology for Clinical Settings Volume 14 - 2023 | https://doi.org/10.3389/fpsyg.2023.1088086
Language: Английский
Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 12
Published: April 9, 2025
Vitamin D is known to have a potential impact on cognitive function and mental health. This study aims assess the association between dietary vitamin intake performance, as well depression, in an elderly U.S. population. Data from National Health Nutrition Examination Survey (NHANES) 2013-2014 were analyzed. A total of 1,344 participants categorized into three tertiles based their (D2 + D3). Cognitive was measured using Consortium Establish Registry for Alzheimer's Disease (CERAD) test, Digit Symbol Substitution Test (DSST), Animal Fluency Test, while depression assessed through Patient Questionnaire-9 (PHQ-9). Adjustments made confounding variables, including age, sex, race, education, physical activity level, other factors. After adjustment confounders, individuals 3rd tertile (≥4.9 mcg/day) had significantly reduced odds low performance CERAD test (OR: 0.77, 95% CI: 0.57-0.98; p = 0.031) 0.63, 0.49-0.85; 0.013) compared 1st (≤2.4 mcg/day). Similarly, lower (PHQ-9 score > 4) after 0.68, 0.48-0.99; 0.046). Our findings suggest that associated with improved depressive symptoms individuals. However, further longitudinal studies are needed establish causality explore underlying mechanisms.
Language: Английский
Citations
0
BMC Geriatrics, Journal Year: 2025, Volume and Issue: 25(1)
Published: April 14, 2025
Abstract Background The number of people living with dementia and/or cognitive impairment worldwide is rising a negative effect on quality life for many older adults. This study aims to examine the factors associated function among adults in Kuwait. Methods cross-sectional recruited 253 ≥ 60 years from Geriatric outpatient unit Cognitive (dependent variable) was assessed using Arabic version Mini-Mental State Examination (MMSE) scores < 24 indicative impairment. Biochemical, nutritional, clinical, lifestyle, anthropometric, and sociodemographic independent variables were included. Results A normal MMSE score reported 51.0% ( n = 129) sample, 34.7% 14.2% participants having mild moderate/severe impairment, respectively. Multivariate ordinal logistic regression analysis indicated that Type 2 diabetes more than double odds (OR 2.15, 95% CI: 1.19–3.94; P 0.01). Each additional level education lower likelihood 0.34, 0.26–0.43; 0.001). Conclusion identifies key risk Kuwaiti These findings underscore need targeted interventions mitigate decline aging populations provide context-specific data support policy decisions.
Language: Английский
Citations
0
Discover Mental Health, Journal Year: 2025, Volume and Issue: 5(1)
Published: May 1, 2025
Post-COVID-19 Syndrome (PCS) is defined as symptoms persisting beyond 12 weeks from the onset of symptoms. Notably, COVID-19 has been associated with long-term effects on brain and mental health. This cross-sectional study aims to investigate depression, fatigue, sleep quality, cognitive dysfunction, particularly working memory, in individuals PCS compared a healthy control group. Between April December 2021, 45 60 met eligibility criteria. Demographic information Montreal Cognitive Assessment were collected. Two visual memory tasks, Delayed Match-to-Sample (DMS) n-back, performed, along self-report questionnaires: Beck Depression Inventory, Modified Fatigue Impact Scale, Pittsburgh Sleep Quality Index. A total 105 participants enrolled. Findings reveal that group exhibited notably higher levels impairment (13.3% vs. 1.6%, p = 0.04), depression (53.9% 25.9%, 0.03), disturbances 18.6%, 0.01) latency duration affected. No significant differences function observed between two groups (p 0.90 for DMS 0.98 n-back). The highlights prevalence disturbance, phase, inflammation likely playing role. Moreover, suggests untreated may pose risks dementia. Understanding underlying mechanisms crucial developing effective interventions support recovering infection. Prospective longitudinal studies larger more diverse samples are warranted confirm expand upon these findings.
Language: Английский
Citations
0
Egyptian Journal of Basic and Applied Sciences, Journal Year: 2024, Volume and Issue: 11(1), P. 334 - 353
Published: April 17, 2024
This research aimed to investigate the possible anti-amnesic effects of a combined therapy involving melatonin and H2S in rat model displaying Depressive-Like Behaviors caused by Chronic Unpredictable Mild Stress (CUMS). Our study aims assess efficacy this treatment mitigating oxidative stress neuroinflammation striatum hippocampus. Furthermore, we seek its ability restore BDNF levels within specific model. The rats underwent 4-week CUMS protocol were administered sodium hydrosulfide (a donor) at dose 5.6 μmol/100 g/day, as well 1 mg/100 g/day from first day protocol. Following exposure, assessed through various behavioral tests. Subsequently, euthanized after tests, blood samples collected for corticosterone analysis. Oxidative (OS) markers, TNF-α analyzed both HP. Concurrently administering CUMS-induced depression demonstrates antidepressant-like effects. effectively prevents development learning memory impairments associated with CUMS. Additionally, it reduces Malondialdehyde nitric oxide levels, enhances glutathione peroxidase superoxide dismutase activity HP, mitigates elevations brain regions. Significantly, long-term administration combination reverses chronic stress-induced reduction hippocampal levels. These findings suggest that synergy between holds promise alleviating cognitive impairments.
Language: Английский
Citations
3
IBRO Neuroscience Reports, Journal Year: 2024, Volume and Issue: 17, P. 441 - 455
Published: Nov. 8, 2024
Language: Английский
Citations
3
International Journal of Environmental Research and Public Health, Journal Year: 2023, Volume and Issue: 20(7), P. 5328 - 5328
Published: March 30, 2023
Depression is the most common psychiatric condition that occurs after cerebrovascular accident, especially within first year stroke. Poststroke depression (PSD) may occur due to environmental factors such as functional limitations in daily activities, lower quality of life, or biological damage areas brain involved emotion regulation. Although many are hypothesized increase risk PSD, relative contribution these not well understood.We evaluated which cross-sectional variables were associated with increased odds PSD our adult outpatient stroke neuropsychology clinic population.The sample included 325 patients (49.2% female; mean age 59-years old) at an average 8.1 months ischemic hemorrhagic Variables logistic regression characteristics, demographics, psychosocial factors, comorbid medical problems, conditions, and cognitive status. The Mini International Neuropsychiatric Inventory was used determine DSM-defined anxiety disorders. A standard neuropsychological test battery administered.PSD occurred 30.8% sample. Logistic indicated a disorder (5.9 times more likely suffer from p < 0.001). Further, history treatment before (3.0 PSD), fatigue (2.8 likely), memory impairment (2.4 younger (all values 0.006).Results suggest multifactorial extends literature by demonstrating correlated strongest PSD. screening plans should address only but anxiety.
Language: Английский
Citations
8
The Science of The Total Environment, Journal Year: 2024, Volume and Issue: 923, P. 171535 - 171535
Published: March 6, 2024
Language: Английский
Citations
2
Frontiers in Global Women s Health, Journal Year: 2024, Volume and Issue: 5
Published: June 13, 2024
Background Evidence suggests that a combination of biological and social factors influence risk dementia differently for women men. In healthy older women, several may contribute to changes in cognition. Objective Describe the characteristics associated with variation cognition sample cognitively Panamanian women. Methods The study includes cross-sectional analyses cognitive domains at baseline ( n = 357) 17-month (SD 2.0) follow-up 200) aged 60 years enrolled Panama Aging Research Initiative-Health Disparities (PARI-HD) study. Instruments included clinical questionnaires, physiological measures, neuropsychological test battery assessing global seven domains. Multiple regression examined associations between demographic baseline. Repeated measures were used investigate from follow-up. Results On average, participants 68.6 age 5.9) 16.1 education 4.7). Age, income, showed robust Subjective impairment was lower performance cognition, verbal learning, memory Only attention domain decreased follow-up, subjective health state depressive symptoms significantly predicted change attention. Discussion Our findings investigation Hispanic understanding sociodemographic health-related decline progression dementia.
Language: Английский
Citations
1
Pharmacopsychiatry, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 23, 2024
Abstract Introduction The relationship between antidepressant use and class with cognition in depression is unclear. This study aimed to evaluate the association of depressive symptoms (class, duration, number). Methods Data from National Health Nutrition Examination Survey were examined for cognitive function through various tests memory issues Medical Conditions questionnaire. Depressive assessed using Patient Questionnaire-9. Results A total 2867 participants included. Participants had significantly higher odds impairment (CI) on animal fluency test (aOR=1.89, 95% CI=1.30, 2.73, P=0.002) Digit Symbol Substitution (aOR=2.58, CI=1.34, 4.9, P=0.007), as well subjective (aOR=7.25, CI=4.26, 12.32, P<0.001) than those without depression. There no statistically significant associations any CI categories treated an duration. who more one antidepressant. Specifically, users atypical antidepressants, selective serotonin reuptake inhibitors, or tricyclic antidepressants (TCAs) comparison TCAs showing largest (aOR=4.21, CI=1.19, 14.86, P=0.028). Discussion highlights symptoms, use, CI. Future studies should further mechanism underlying this phenomenon.
Language: Английский
Citations
1
BMC Complementary Medicine and Therapies, Journal Year: 2024, Volume and Issue: 24(1)
Published: Nov. 15, 2024
Psychological anxiety and depression, as well memory impairment, are frequently linked to inflammation. Clove essential oil (CEO) administration hydrogen (H2) inhalation have been proven anti-inflammatory alleviating effects on related psychological disorders in the past. The current study investigated potential improve anxiety-like behaviors cognitive function by a combination of CEO H2 treatment. mice were administered lipopolysaccharide (LPS) induce inflammation oxidative stress response cause disorders. Using this animal model, we conducted experiments test whether could damage behavior caused LPS. Subsequently, elevated plus maze (EPM), forced swimming (FST), passive avoidance (PA) performed for evaluation anxiety, electric shock, respectively. Furthermore, biochemical analysis was used examine expression levels inflammatory markers. Our results showed that alone or positively improved inflammation-induced deficits mice. In single treatment groups, demonstrated better than maze, swimming, tests, while combined with both provided further enhancement effect. Biochemical cerebral cortex revealed therapy reversed LPS-induced response. suggest has treat neuropsychiatric
Language: Английский
Citations
1