The effects of enhanced external counter-pulsation on post-acute sequelae of COVID-19: A narrative review

Open Medicine, Journal Year: 2025, Volume and Issue: 20(1)

Published: Jan. 1, 2025

Abstract Some of the millions patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have developed new sequelae after recovering from initial disease, termed post-acute disease 2019 (PASC). One symptom is anxiety, which likely due to three etiologies: brain structural changes, neuroendocrine disruption, and neurotransmitter alterations. This review provides an overview current literature on pathophysiological pathways linking as well possible mechanisms action in increasingly scrutinized treatment method, enhanced external counter-pulsation (EECP), able alleviate anxiety. SARS-CoV-2 triggers increased inflammatory cytokine production, oxidative stress; these processes contribute aforementioned etiologies. The potential approach EECP, involving sequenced inflation deflation specifically-placed airbags, has become increasing interest, it been found PASC-associated anxiety by improving patient cardiovascular function. These functional improvements were achieved EECP stimulating anti-inflammatory pro-angiogenic processes, endothelial cell function coronary blood flow, partially via counteracting against negative effects infection renin–angiotensin–aldosterone system. Therefore, could promote both psychosomatic cardiac rehabilitation. Further research, though, still needed fully determine its benefits mechanism action.

Language: Английский

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Differential Fatigue Profile in Patients with Post-COVID Condition, Fibromyalgia, and Multiple Sclerosis

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 952 - 952

Published: Feb. 2, 2025

Background/Objectives: Fatigue is a prevalent and debilitating symptom in Post-COVID Condition (PCC), fibromyalgia, multiple sclerosis (MS). Although these conditions share clinical similarities, the underlying mechanisms of fatigue across may differ remain poorly understood. This study aimed to compare intensity characteristics three identify shared distinct features. Methods: We conducted cross-sectional involving 429 participants: 219 with PCC, 112 98 MS. Participants completed questionnaire specifically developed for via Google Forms platform. was by group professionals hospital specializing related conditions, collaboration expert patients. The reported following Checklist Reporting Results Internet E-Surveys (CHERRIES) recommendations. Results: significantly higher PCC fibromyalgia compared Some differences were observed: MS patients more response heat greater impact mood on fatigue. Furthermore, delayed reduced benefits from rest pronounced both fibromyalgia. No significant found regarding cognitive or difficulties predicting ability perform activities. Conclusions: These results underscore some quality findings could suggest different pathophysiology Our underscores need tailored diagnostic tools interventions managing conditions.

Language: Английский

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Persistent Symptoms and Associated Risk Factors of COVID-19: A Cross-Sectional Study in Minia, Upper Egypt

Healthcare, Journal Year: 2025, Volume and Issue: 13(7), P. 699 - 699

Published: March 22, 2025

Background: A significant number of COVID-19 survivors around the world have been reporting persistent symptoms following their recovery. Long COVID is recognized as a condition affecting not only respiratory but also gastrointestinal, cardiovascular, neurological, immune, and hematopoietic systems. Objective: This study aimed to describe in six months post-infection Minia, Upper Egypt, investigate associated risk factors. Methods: observational cross-sectional included 189 hospitalized non-hospitalized patients previously diagnosed with COVID-19. Demographic data, symptom severity, comorbidities, were collected. logistic regression analysis was used identify factors long COVID, statistical significance set at p < 0.05. Results: In total, 68.8% participants women, 83.5% reported least one ongoing symptom. The most self-reported fatigue (73.5%) myalgia (45.5%), followed by dyspnea (43.3%). Age an increased developing (OR 1.028, 95% CI 1.003-1.054, = 0.030). Patients who during acute phase had more than twice risks having 2.384, 1.055-5.387, 0.037). Conclusions: substantial proportion continues experience symptoms, primarily constitutional neurological manifestations. Many self-medicating unprescribed antibiotics, highlighting need for public awareness regarding viral infections improper antibiotic use.

Language: Английский

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Assessment of Post-COVID-19 Syndrome and Its Relationship to Age, Sex, and Comorbid Disease in Iraqi Population

Medical Journal of Babylon, Journal Year: 2025, Volume and Issue: 22(1), P. 33 - 40

Published: Jan. 1, 2025

Abstract Background: Post-coronavirus disease (post-COVID-19 syndrome) is any signs or symptoms that began during COVID-19 infection and persisted for at least 12 weeks after the first onset of infection. Objective: The study aimed to assess post-COVID-19 in Iraqi patients evaluate their incidence relationships with patients’ age, sex, comorbid disease, vaccination status. Materials Methods: This was a cross-sectional using well-designed questionnaires recovered patients. collected data were summarized analyzed specific analytical program. Results: About 915 participated study, male 283 (30.9%) female 632 (69.1%). 619 (67.7%) participants reported one symptom. Fatigue most common postviral symptom which occurs 365 (39.9%) patients, followed by hair loss 286 (31.3%) decreases cognitive functions like forgetfulness 263 (28.7%) decreased mental performance 248 (27%). syndrome significantly related gender, severity COVID-19, preexisting diseases. In addition, this found reduced vaccination. Conclusion: Post-COVID-19 affect many healing from acute are mostly coronavirus infection, associated comorbidities. Follow-up may be required minimize effects on general health quality life affected

Language: Английский

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Exercise Capacity and Occupational Competence Sequelae in COVID-19 Survivors: A Longitudinal Study

Occupational Therapy In Health Care, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 17

Published: April 9, 2025

The Sars-Cov-2 infection disease (COVID-19) causes symptoms during both acute and post-COVID phases. This study assessed exercise capacity occupational competence of 20 hospitalized COVID-19 patients, at discharge three months later using the 6-Minute Step Test Occupational Self-Assessment. Significant differences were found in scores between (p < 0.05). However, these measurements not correlated > Although patients show improvement after discharge, some persisted, affecting their exercise, performance. Further research is needed to explore long-term outcomes beyond one year.

Language: Английский

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