Do Medical and Recreational Marijuana State Laws Impact Trends in Postoperative Opioid Prescriptions Among Patients Who Have Undergone TJA?

Clinical Orthopaedics and Related Research, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 19, 2025

Background Total joint arthroplasty (TJA) is a painful procedure frequently managed with opioid medication, which puts patients at risk for chronic use. Marijuana pain modifier and may be an effector of opioid-use reduction. Recently, many states have legalized the use medical recreational marijuana, these legalization events correlated reductions in prescriptions. This trend has not yet been demonstrated context orthopaedic surgery, there limited evidence overall investigating effect marijuana on perioperative TJA. Question/purposes (1) Is associated changes who undergone TJA? (2) (3) Are observed any specific subpopulations Methods The MarketScan Commercial Medicare Supplemental Claims Encounters Database was queried to assess relative THA TKA between May 1, 2017, September 30, 2021, around after time that crisis declared public health emergency. We identified 129,132 inpatient TJA procedures (THA = 49,718, 79,414). period defined as 30 days before surgery 90 surgery. used effective dates all 50 Washington, DC conduct difference-in-difference analysis compare trends outpatient prescriptions among underwent legalizations or those without change status. Results no impact morphine milligram equivalent (MME)/day (difference-in-difference 4.38 [95% confidence interval (CI) -4.49 13.22]). However, implementation increase MME/day 8.83 CI 0.22 17.43]). When we looked patient groups, implementations laws were both increases women, while increased undergoing prior opioids. Conclusion did identify differences respect implementation. found important because surgeons law should aware potential availability their how this postoperative course, particularly utilization. Level Evidence III, therapeutic study.

Language: Английский

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Exploring perceived gender norms about Cannabis among treatment-seeking adults in the era of Cannabis legalization in Canada: A qualitative analysis

Journal of Substance Use and Addiction Treatment, Journal Year: 2025, Volume and Issue: 172, P. 209684 - 209684

Published: March 20, 2025

Language: Английский

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Effects of sexual assault vs. other traumatic experiences on emotional and cannabis use outcomes in regular cannabis users with trauma histories: moderation by gender?

Frontiers in Psychology, Journal Year: 2024, Volume and Issue: 15

Published: May 31, 2024

Introduction While sexual assault may have particularly adverse emotional effects compared with other forms of trauma, it remains unclear which outcome dimensions are impacted, whether cannabis outcomes similarly and gender differences exist in assault’s links these outcomes. Methods N = 100 users trauma histories ( M age 33.1) completed standardized measures demographics, exposure, posttraumatic stress (PTS) depressive symptoms, hopelessness, (frequency, medicinal prescription, motives, craving). Results Sexual was experienced more often by women (83.9%) than men (31.8%). A series 2 × analyses variance [gender: n 56) vs. 44) type: 61) 39)] logistic regression revealed that survivors scored higher on re-experiencing hyperarousal PTS symptoms (DSM-5 Clusters B E), cognitive use frequency, to cope psychological compulsivity craving; lower social enhancement motives. In terms main effects, negative emotions. interactions for Cluster D (negative alterations mood/cognitions), among only, survivors; motives purposefulness craving, men. Discussion Across many different survivors’ affect should be a specific therapeutic focus. Moreover, we identified clinical concern regardless gender. Finally, interest survivors, while treatment targets men, craving women.

Language: Английский

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The Roles of Cannabis Potency and Gender in Cannabis Dependence and Anxiety in Recent Cannabis Users with Trauma Exposure Histories

Pharmacological Research, Journal Year: 2025, Volume and Issue: unknown, P. 107586 - 107586

Published: Jan. 1, 2025

Over the past 20 years, levels of Δ9-tetrahydrocannabinol (THC) in cannabis have significantly increased, while cannabidiol (CBD) increased much less comparison. Cannabis with higher THC potency (commonly assessed via THC:CBD ratio) may increase risk for dependence and trigger/exacerbate anxiety. However, few studies effects on anxiety examined gender moderation. Additionally, there are issues how is calculated ratio that contribute to inconsistencies literature. N = 202 (55.8% women) recent users (>1g month) trauma histories - a group at high completed an online survey including self-report measure CBD participants' typically-used product. was as (THC%/CBD%) relative proportion (THC%/[THC%+CBD%]). were self-reported Use Disorder Identification Test-Revised (CUDIT-R) Generalized Anxiety Disorder-7 (GAD-7), respectively. Consistent prior findings general population, positively correlated dependence, p =.002, levels, =.020, but only when not ratio. research, women reported also unexpectedly, ratios, than men. No significant differences found associations either outcome variable. Results consistent reports convergence use prevalence. these results identify superior predictor adverse outcomes both men women.

Language: Английский

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Characterization of Cannabis usage in individuals with non-cancer chronic pain in the state of Maine using the Behavioral Risk Factor Surveillance System (BRFSS)

Deleted Journal, Journal Year: 2025, Volume and Issue: 22(1)

Published: Jan. 21, 2025

One in 3 Mainers experiences chronic pain. Maine legalized medical and recreational cannabis usage 2009 2016, respectively. To assess with pain, we obtained data from Maine's Behavioral Risk Factor Surveillance System (BRFSS), an annual anonymous survey, 2017 to 2020. BRFSS began asking frequency of 2017, two follow-up questions regarding administration routes reasons for use added We identified individuals pain as those that reported having a rheumatoid condition diagnosis, controls who no such conditions. focus on non-cancer excluded had previous cancer diagnoses. For each the three separate questions, also answered "don't know/unsure" or "refused" question interest their sex. Data 2020 were used analyze usage, while alone questions. stratified by sex analyzed Microsoft Excel SigmaPlot. observed increase high-frequency users (21–30 days/last 30 days) reduction non-users both sexes 2020, which was significant (p < 0.05). The average age lower than non-users, regardless status Regardless status, although smoking overall most route, more males tended smoke females eat it 0.01). Individuals sex, likely respond, "use some other way" Pain group males, females, control all report 0.001). Since legalization cannabis, have started frequently. High-frequency are generally younger non-users. Females reasons, smoking. Further characterization is warranted becomes prevalent without

Language: Английский

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Marijuana use among adolescent Asian Americans and Pacific islanders: Analysis of ethnic subgroup and gender differences

Preventive Medicine Reports, Journal Year: 2025, Volume and Issue: 52, P. 103016 - 103016

Published: Feb. 25, 2025

To assess heterogeneity in marijuana use among adolescent Asian American and Pacific Islander (AAPI) subgroups. AAPI high school students (n = 31,071) participating the 2019-2020 California Student Tobacco Survey were categorized by race/ethnicity examined for ever current (past-30-day) use. Descriptive statistics used to describe harm perceptions Multiple logistic regression was compare subgroups on with other demographics as covariates. Current rates ethnic were: Chinese 4.2 %, Koreans 4.9 Indians 5.2 Vietnamese 6.0 Hmong 6.4 Pakistanis 6.6 Japanese 9.4 Filipinos 9.6 Cambodians 17.9 monoethnic Asians 10.5 Islanders 22.3 %. monoethnic, multiethnic, multiracial AAPIs 7.3 9.1 18.5 respectively, using at a higher rate than multiethnic (both p's < 0.001). Among overall, 11.3 % currently marijuana. Females males, 10.8 vs. (p .011). Ever negatively correlated that everyday occasional is harmful (all Compared students, all except more likely 0.05), Filipinos, Japanese, Cambodians, twice There substantial of adolescents. Several elevated rates. Gender-based trendlines adolescents have crossed.

Language: Английский

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Patterns of Cannabis Use among Women With HIV in the United States

AIDS and Behavior, Journal Year: 2025, Volume and Issue: unknown

Published: March 7, 2025

Language: Английский

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Exploring cannabis consumption stigma in Canada with consideration of age and gender differences

Addictive Behaviors Reports, Journal Year: 2025, Volume and Issue: unknown, P. 100608 - 100608

Published: April 1, 2025

Language: Английский

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Relationship Between Cannabis Dispensary Density, Proximity, and Attitudes Toward Medical Cannabis: A Cross‐Sectional Study

Health Science Reports, Journal Year: 2025, Volume and Issue: 8(4)

Published: April 1, 2025

ABSTRACT Background and Aims Public attitudes toward medicinal cannabis (MC) remain mixed, particularly in areas with legal access to recreational (RC). This study aimed explore the relationship between proximity dispensaries, dispensary density, MC. Specifically, we hypothesized that individuals living closer dispensaries or higher density would have more negative Methods Data were collected through an online survey administered from February July 2021 March May 2022. Respondents' MC measured using Medical Cannabis Attitudes Scale (MCAS), their zip code was used calculate proximity. Statistical analyses included Spearman's rank‐order correlation, ANOVA assess relationships attitudes, distance, a Generalized Least Squares regression analysis evaluate demographic, social, geographic predictors MCAS scores. Results A total of 935 respondents participated, 743 residing codes no 160 moderate‐density codes, 32 high‐density codes. weak positive correlation found greater distance favorable MCAS, r s (933) = 0.090, p < 0.05. However, there statistically significant difference scores different groups (F(2932) 0.683, 0.505). The overall model significant, F (9918) 2.62, 0.005, R 2 0.025; gender ( 0.004), age 0.048) state status 0.001) contributed significantly model. Conclusion provides evidence MC, contributing while did not impact attitudes. neither nor These findings suggest may influence factors impacting require further investigation.

Language: Английский

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Beneficial and adverse effects of THC on cognition in the HIV-1 transgenic rat model: Importance of exploring task- and sex-dependent outcomes

Brain Behavior and Immunity, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

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