Beyond Medication: The Impact of Physical Activity and Herbal Options in Managing Depression DOI
Jerome Adadzi, Nicholas A Kerna

Scientia. Technology, science and society., Journal Year: 2024, Volume and Issue: 1(3), P. 62 - 85

Published: Dec. 1, 2024

Physical activity has been gaining recognition as a key component in managing depression, with its physiological, biochemical, and neurological effects playing crucial role improving mental health. Exercise enhances neuroplasticity, promotes the release of mood-regulating neurochemicals, reduces stress, all contributing to alleviating depressive symptoms. Also, lifestyle modifications, including physical activity, are increasingly integrated into clinical practice essential non-pharmacological interventions for depression. Alongside these interventions, growing St. John’s wort (SJW) an effective treatment mild moderate depression underscores potential alternative or adjunct conventional antidepressants. Both SJW represent promising approaches comprehensive offering safe, effective, well-supported options individuals struggling disorders. This review will explore integration exercise SJW, management.

Language: Английский

The Impact of Deprescribing Interventions on the Drug Burden Index and Other Outcomes: A Systematic Review DOI

Bonnie M. Liu,

Mitchell R. Redston, Kenji Fujita

et al.

Journal of the American Medical Directors Association, Journal Year: 2024, Volume and Issue: 25(7), P. 105021 - 105021

Published: May 17, 2024

Language: Английский

Citations

4
Music-Based Cognitive Training for Adults with Major Depressive Disorder and Suicide Risk: A Pilot Study DOI Open Access

Melissa Tan,

Steffi Friyia,

Corene Hurt-Thaut

et al.

Journal of Clinical Medicine, Journal Year: 2025, Volume and Issue: 14(3), P. 757 - 757

Published: Jan. 24, 2025

Background/Objectives: Cognitive challenges in attention and executive function worsen over time individuals with major depressive disorder (MDD) suicidal risk. These difficulties persist beyond acute episodes, limited targeted treatments available. Neurologic music therapy (NMT) is effective for cognitive rehabilitation brain injuries developmental disabilities, suggesting potential benefits adults MDD suicide This pilot study evaluated the feasibility, acceptability, preliminary effectiveness of short-term NMT on MDD. Methods: Adults aged 18+ ideations participated an 8-week single-arm open label 45-min individual in-person sessions using musical control training (MACT) (MEFT). Participants provided feedback feasibility pre- post-intervention assessments included neurocognitive tasks questionnaires ideation, symptoms, quality life. Results: A total 18 enrolled, 10 participants completed protocol. Of participants, 100% were satisfied their experience NMT, noting improvements 80% function. experienced some memory (Digit Span Forward Test), flexibility (Trail Making Test B), inhibitory (Stroop Task). Significant reduction ideation intensity (Beck Suicidal Scale Ideation) was observed, as well significant Conclusions: first to demonstrate respect risk, providing data future randomized controlled trials.

Language: Английский

Citations

0
Longitudinal Cognitive Trajectories in Older Adults with Restless Legs Syndrome or Willis–Ekbom Disease DOI Creative Commons
Ioannis Liampas, Vasileios Siokas, Andreas Kyrozis

et al.

Life, Journal Year: 2024, Volume and Issue: 14(4), P. 430 - 430

Published: March 24, 2024

Background: Restless legs syndrome/Willis-Ekbom disease (RLS/WED) has occasionally but not consistently been associated with cognitive and most notably language executive impairment. The present study was conducted to investigate the trajectories of older individuals RLS/WED. Methods: Participants were drawn from randomly selected, (>64 years), population-based HELIAD cohort. Individuals without dementia available neuropsychological evaluations at baseline follow-up considered for potential eligibility. A comprehensive assessment examining five principal components cognition (memory, visuo-spatial ability, attention, function, language) administered participants. Generalized estimating equation analyses used examine unadjusted adjusted (for critical factors covariates) effects RLS/WED on over time. Results: total 1003 predominantly female (59.5%), (72.9 ± 4.9 years) participants after a mean 3.09 0.85 years included in study. Among them, 81 diagnosed baseline. Global cognition, memory, visuo-perceptual skills did differ between those However, group performed worse by standard deviation 0.249, while demonstrating mitigated decline time, 0.063. models yielded similar results. Conclusions: Our findings indicative disadvantage among RLS/WED, initial discrepancy tends dissolve

Language: Английский

Citations

0
Exploring the Effects of Sensorimotor Training and Relaxation Therapy on Postural Control, Balance, Sleep, and Stress in Sedentary Young Adults: Rationale, Design, and Methodology DOI Open Access
Tarushi Tanwar, Mosab Aldabbas, Iram Iram

et al.

Current Protocols, Journal Year: 2024, Volume and Issue: 4(8)

Published: Aug. 1, 2024

Abstract Postural control (PC) and sleep are critical in several aspects of health. Poor negatively influences PC balance, which is necessary for performing various tasks, from reaching to mobility. Moreover, disturbances consequent balance deterioration associated with job accidents, traffic falls, injuries. Healthy adults who have inadequate show a decline optimal functioning, even the absence medical illnesses. This suggests that getting enough sleep, both duration quality, essential maintain has also been observed bidirectional relationship stress levels. However, there insufficient evidence regarding impact non‐pharmacological treatments improve PC, sedentary young adult (YA) population. article describes protocol study investigate effects sensorimotor training relaxation therapy on static dynamic tests, measures, subjective objective indices among YAs impaired quality. The designed evaluate effect these therapies fatigue, salivary cortisol levels, anxiety, depression. Methods assessing architecture, described along methods scoring primary goal providing standardized set assessment procedures according latest guidelines gold‐standard techniques measures can be used reliably at different laboratories. © 2024 Wiley Periodicals LLC. Basic Protocol 1 : 2 Balance 3 Sleep architecture 4 Salivary analysis

Language: Английский

Citations

0
Psychometric testing of a new instrument for assessing individual's mindfulness, abilities, and well-being outcomes: The Leaf Mind Management (LMM) scale DOI
Caroline Leaf, Robert P. Turner,

René Paulson

et al.

Current Psychology, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 4, 2024

Language: Английский

Citations

0
Prevalence of Antidepressant Prescription in Adolescents Newly Diagnosed with Depression in Germany DOI Creative Commons
Nimran Kaur, Corinna Doege, Karel Kostev

et al.

Children, Journal Year: 2024, Volume and Issue: 11(10), P. 1246 - 1246

Published: Oct. 16, 2024

Depression is the most common mental illness in world, found nearly three ten adolescents globally. This study aims to evaluate prevalence of antidepressant prescriptions and types therapy administered among diagnosed with depression Germany.

Language: Английский

Citations

0
Human-Induced Pluripotent Stem Cell-Derived Neural Organoids as a Novel In Vitro Platform for Developmental Neurotoxicity Assessment DOI Open Access

Tsunehiko Hongen,

Kenta Sakai,

Tomohiro Ito

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(23), P. 12523 - 12523

Published: Nov. 21, 2024

There has been a recent drive to replace in vivo studies with vitro the field of toxicity testing. Therefore, instead conventional animal or planar cell culture models, there is an urgent need for systems whose conditions can be strictly controlled, including cell-cell interactions and sensitivity low doses chemicals. Neural organoids generated from human-induced pluripotent stem cells (iPSCs) are promising platform modeling human brain development. In this study, we developed new tool based on various iPSCs study predict chemical-induced humans. The model displayed several neurodevelopmental features showed good reproducibility, comparable that previously published models. results revealed basic fibroblast growth factor plays key role formation embryoid body, as well complex neural networks higher-order structures such layered stacking. Using organoid pesticide toxicities were assessed. Cells treated concentrations rotenone underwent apoptosis greater extent than those high rotenone. Morphological changes associated development progenitor observed after exposure chlorpyrifos. These findings suggest neuronal mimic developmental processes occurring nerves useful evaluating drug efficacy, safety, toxicity.

Language: Английский

Citations

0
Beyond Medication: The Impact of Physical Activity and Herbal Options in Managing Depression DOI
Jerome Adadzi, Nicholas A Kerna

Scientia. Technology, science and society., Journal Year: 2024, Volume and Issue: 1(3), P. 62 - 85

Published: Dec. 1, 2024

Physical activity has been gaining recognition as a key component in managing depression, with its physiological, biochemical, and neurological effects playing crucial role improving mental health. Exercise enhances neuroplasticity, promotes the release of mood-regulating neurochemicals, reduces stress, all contributing to alleviating depressive symptoms. Also, lifestyle modifications, including physical activity, are increasingly integrated into clinical practice essential non-pharmacological interventions for depression. Alongside these interventions, growing St. John’s wort (SJW) an effective treatment mild moderate depression underscores potential alternative or adjunct conventional antidepressants. Both SJW represent promising approaches comprehensive offering safe, effective, well-supported options individuals struggling disorders. This review will explore integration exercise SJW, management.

Language: Английский

Citations

0