Cureus, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 14, 2024
Retinopathy, small fiber neuropathy (SFN), and encephalopathy associated with recoverin antibodies have not been previously reported as side effects of BNT162b2 vaccination in a patient HLA-B27-associated spondylarthritis. The is 47-year-old male 10-year history spondylarthritis without recurrence, who developed acute post-acute COVID syndrome (ACVS/PACVS) after the first dose vaccine. PACVS manifested cerebral disease, eye SFN. Two years onset adverse effects, recurrent elevated were detected. Despite administration various treatments, most symptoms persisted for more than three years, only few interventions such glucocorticoids, hyperbaric oxygen therapy, botulinum toxin, inuspheresis, HELP (heparin-induced extracorporeal LDL precipitation) apheresis showed transient beneficial effect. In conclusion, this case offers an example collection following SARS-CoV-2 (SC2V) specific autoimmune disorder positivity anti-recoverin antibodies. These clinical manifestations may be triggered by exaggerated immune response known multisystemic inflammatory adults to SC2V. Clinicians should report other similar cases determine if pattern exists.
Language: Английский