
JMIR Research Protocols, Journal Year: 2024, Volume and Issue: 14, P. e54221 - e54221
Published: Nov. 13, 2024
Background Inhibitory deficits are common in psychopathology. Emotion-related impulsivity (ERI) and rumination general risk factors for psychiatric distress that similarly associated with dysfunctional inhibition—particularly affective contexts. A number of cognitive remediation procedures have been developed to improve inhibitory control; however, most programs focus on “cold” cognition independent processing. This pilot trial will gather preliminary evidence a new training intervention targeting “hot” control (ie, functions during elevated emotional arousal) transdiagnostic sample adults who report heightened emotion dysregulation. Objective manuscript describes protocol randomized waitlist-controlled assess changes ERI after neurobehavioral (N-ACT), an 8-week designed response inhibition working memory. Our primary aim is evaluate the efficacy, feasibility, acceptability N-ACT reducing ERI, which we respectively conceptualize as complementary behavioral consequences Secondarily, examine whether leads improvements and, more distally, psychopathology symptoms. Methods The final comprise 80 high or rumination. Participants be (1) begin program without delay (2) join waitlist condition then complete N-ACT. Exclusion criteria include active alcohol substance use disorders, psychosis, suicide risk. At baseline postintervention time points, participants measures dysregulation symptoms, well neuropsychological assessment control. Individuals assigned group undergo identical before joining waitlist, followed by parallel assessments Results funded support from University California Board Regents Peder Sather Foundation (funding period: October 2022-September 2025). Recruitment scheduled spring 2025. We data analysis once collection complete, planned occur fall Conclusions initial N-ACT, novel approach address 2 key contributors psychopathology: uses computerized adaptive tasks strengthen processes theoretically empirically linked hope this work help inform future studies sufficient statistical power ascertain enhancing through (N-ACT) produces downstream reductions symptoms via improved regulation. Trial Registration ClinicalTrials.gov NCT06226467; https://www.clinicaltrials.gov/study/NCT06226467; Open Science Framework Registry rak5z; https://osf.io/rak5z International Registered Report Identifier (IRRID) PRR1-10.2196/54221
Language: Английский