
Biomedicines, Journal Year: 2025, Volume and Issue: 13(4), P. 893 - 893
Published: April 7, 2025
Background/Objectives: The association between glaucoma and autonomic nervous system (ANS) function remains unclear. Primary open-angle (POAG) exfoliation (EXG) have distinct pathophysiological mechanisms, which may lead to different ANS alteration. This study aimed investigate the subtypes following time-domain heart rate variability (HRV) parameters: standard deviation of normal-to-normal intervals (SDNN), square root mean sum squared differences adjacent (RMSSD), coefficient variation R-R (CVRR). Methods: A total 809 eyes from patients with POAG, EXG, controls were included. HRV was measured participants’ fingertips using a sphygmograph (TAS9 Pulse Analyzer Plus View; YKC Corp., Tokyo, Japan). Comparisons parameters among groups conducted. To evaluate associations other variables, linear regression analyses Results: included 522 participants 191 96 in control group. There significant difference CVRR (the group: 4.04 ± 2.08%, POAG 3.86 1.87%, EXG 3.57 2.02%; p = 0.010), whereas no found SDNN RMSSD. group had significantly lower values compared (p 0.0156 0.0037, respectively). In multivariate analysis, highest recorded intraocular pressure (IOP) associated CVRR. Conclusions: reflect alterations subtypes.
Language: Английский