Vaccine hesitancy in context of COVID-19 in East Africa: systematic review and meta-analysis DOI Creative Commons
Melsew Setegn Alie, Gossa Fetene Abebe, Yilkal Negesse

et al.

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Oct. 12, 2024

The outbreak of the SARS-CoV-2 pandemic has had a significant impact on human lives, and development effective vaccines been promising solution to bring an end pandemic. However, success vaccination program heavily relies portion population being vaccinated. Recent studies have indicated rise in vaccine hesitancy over time inconsistent factors affecting it. This study aimed synthesis pooled prevalence COVID-19 associated among various communities East Africa. review encompassed relevant descriptive observational conducted between January 1, 2020, December 26, 2023. We browsed databases, including PubMed, Google Scholar, Scopus, African online Journal, cross-references, Web Science. After extracted exported R data analysis was performed using version 4.2. Meta-package were used estimate hesitancy. Publication bias assessed through funnel plots, Egger's test, trim-and-fill methods. carefully screening initial pool 53,984 studies, total 79 included this systematic meta-analysis. overall 40.40% (95% CI: 35.89%; 45.47%, I2: 99.5%). Identified influencing hesitance female sex, under 40 years old, inadequate prevention practices, relying web/internet as source information, having negative attitude towards vaccine, uncertainty about safety, fear adverse effects, contracting COVID-19, belief conspiracy myths. Approximately four out ten individuals region express vaccination. A tailored approach that considers socio-demographic context could significantly reduce To achieve high coverage, comprehensive strategy is essential, necessitating substantial social, scientific, health efforts. campaigns within widespread consistent implementation interventions. Registered PROSPERO with ID: CRD42024501415.

Language: Английский

COVID-19 Vaccine Acceptance Rate and Its Factors among Healthcare Students: A Systematic Review with Meta-Analysis DOI Creative Commons
Muhammad Mainuddin Patwary, Mondira Bardhan, Md. Zahidul Haque

et al.

Vaccines, Journal Year: 2022, Volume and Issue: 10(5), P. 806 - 806

Published: May 19, 2022

Healthcare students are clinicians-in-training likely to come into contact with COVID-19 as much other frontline healthcare professionals. It is therefore necessary prioritize vaccinations for this group. We conducted a global systematic assessment of vaccine acceptance rates and related factors among using the PubMed, Scopus, Web Science databases keyword searches in March 2022. found 1779 articles relevant information 31 that matched our inclusion criteria. performed random-effects meta-analysis quality eight-item Joanna Briggs Institute Critical Appraisal test cross-sectional studies. A total 30,272 individuals from 16 countries were studied. Most studies carried out U.S. (n = 6), China 5), Poland India 2), Italy Israel 2). The prevalence rate was 68.8% (95% confidence interval [CI]: 60.8–76.3, I2 100%), hesitancy 25.8% CI: 18.5–33.8, 99%). In country-specific analyses, Romania showed highest (88.0%, 95% 44.5–100%), while Iraq lowest (66.2%, 35.5–90.8%). time-trend we decreased over time. Students concerned about potentially serious side effects less willing accept vaccine. National international interventions should be adopted reduce vaccination these important workers.

Language: Английский

Citations

31
Global disparities in COVID-19 vaccine booster dose (VBD) acceptance and hesitancy: An updated narrative review DOI Creative Commons
Debendra Nath Roy, Nowrin Ferdiousi, Md. Mohabbot Hossen

et al.

Vaccine X, Journal Year: 2024, Volume and Issue: 18, P. 100480 - 100480

Published: March 23, 2024

The global deployment of COVID-19 vaccine booster dose (VBD) has been recognized as a promising therapeutic alliance to provide repeated immunity against the arrival new variants. Despite scientific evidence supports effectiveness periodic doses, reluctance continues thrive. This narrative review aimed examine doses acceptance and summarize an up-to-date assessment potential antecedents associated with VBD acceptance. A comprehensive search was performed in several reputable databases such Medline (via PubMed), Scopus, Google scholar, Web Science from June 10th, 2023, August 1st, 2023. All relevant descriptive observational studies on hesitancy were included this review. total fifty-eight (58) included, Asia representing highest count thirty-one (53 %) studies, Europe eleven (19 %), United States nine (16 other regions (Africa multi-ethnic) seven (12 %). Worldwide, pooled rate 77.09 % (95 CI: 76.28–78.18), willingness (n) = 164189, sample (N) 212,990. lowest reported American regions, respectively, 85.38 85.02–85.73, 32,047, (N 37,533) vs. 66.92 66.56–67.4), 29335, 43,832. However, multi-ethnic areas moderately high 79.13 78.77–79.23, 93,994, 11,8779) 72.16 71.13–72.93, 9276, 12,853), respectively. most common key across countries "equal safety", "efficacy", "effectiveness", post-vaccination "side effects", "community protection" "family protection", "risk-benefit ratio", necessity", "trust, "variants control". Disparities uptake observed globally, rates found Europe, regions. Multiple including safety, efficacy, side effects hesitancy.

Language: Английский

Citations

6
COVID-19 vaccine hesitancy worldwide and its associated factors: a systematic review and meta-analysis DOI Creative Commons
Matin Baghani,

Farzan Fathalizade,

Amir Hossein Loghman

et al.

Science in One Health, Journal Year: 2023, Volume and Issue: 2, P. 100048 - 100048

Published: Jan. 1, 2023

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic has taken a toll on humans, and the development of effective vaccines been promising tool to end pandemic. However, for vaccination program be successful, considerable proportion community must vaccinated. Hence, public acceptance COVID-19 become key controlling Recent studies have shown vaccine hesitancy increasing over time. This systematic review aims evaluate rate related factors in different communities. A comprehensive search was performed Medline (via PubMed), Scopus, Web Science from January 1, 2019 31, 2022. All relevant descriptive observational (cross-sectional longitudinal) were included this review. In meta-analysis, Odds Ratio (OR) used assess effects population characteristics hesitancy, event (acceptance rate) effect measure overall acceptance. Publication bias assessed using funnel plot, Egger's test, trim-and-fill methods. total 135 out 6,417 after screening. meta-analysis 114 studies, including 849,911 participants, showed an 63.1%. addition, men, married individuals, educated people, those with history flu vaccination, higher income levels, comorbidities, people living urban areas less hesitant. Increasing awareness importance overcoming is crucial. Being region, being or educated, having influenza level status, comorbidities are associated

Language: Английский

Citations

16
COVID-19 Vaccine Hesitancy among Behavioral Risk Takers DOI Creative Commons
Monideepa B. Becerra, Benjamin J. Becerra

Vaccines, Journal Year: 2022, Volume and Issue: 10(5), P. 767 - 767

Published: May 12, 2022

The COVID-19 pandemic has emerged as a major public health issue, with vaccines serving vital preventive strategy to lower the global burden. Yet, despite national and local mandates, key sectors of population continue demonstrate compliance rates. In United States, young adults have lowest vaccination rates among adult population. goal our study was utilize largest state-health survey assess determinants such hesitancy in order create targeted interventions for most at-risk groups ensure equitable outcomes disease prevention. We utilized latest available California Health Interview Survey, population-based complex probability survey, evaluate vaccine adults. Survey-weighted descriptive statistics, bivariate multivariable logistic regression analyses were conducted. All statistical tests used p less than 0.05 determine significance. A total 1203 respondents, representative 4,027,462 (ages 18–25 years) included study. Our primary findings note that 24% participants reported they would not be willing take vaccination. Prevalence also significantly higher who current smokers (including electronic cigarettes), when compared non-current (36% vs. 22%). Further, highest prevalence noted identified African-American (51%), had high school degree or (34%), those overweight obese (28%), poor status (22%). Multivariable analysis demonstrated smokers, more double odds reporting hesitancy. both independently associated at least three-fold increase Participants psychological distress, however, likely accepting vaccine. Public efforts improve need efforts, including building trust healthcare system African-Americans promoting easier access knowledge less, well young-adults are currently smoking, targeting behavioral focused on risk aversion.

Language: Английский

Citations

21
From assistance to reliance: Development and validation of the large language model dependence scale DOI

Zewei Li,

Zheng Zhang,

Mingwei Wang

et al.

International Journal of Information Management, Journal Year: 2025, Volume and Issue: 83, P. 102888 - 102888

Published: Feb. 20, 2025

Language: Английский

Citations

0
Economic Value of Vaccines to Address the COVID-19 Pandemic in Hong Kong: A Cost-Effectiveness Analysis DOI Creative Commons
Xuechen Xiong, Victor Jing Li, Bo Huang

et al.

Vaccines, Journal Year: 2022, Volume and Issue: 10(4), P. 495 - 495

Published: March 23, 2022

Objective The coronavirus disease 2019 (COVID-19) pandemic has imposed significant costs on economies. Safe and effective vaccines are a key tool to control the pandemic; however, vaccination programs can be costly. Are benefits they bestow worth incur? relative value of COVID-19 not been widely assessed. In this study, cost-effectiveness analysis was performed provide evidence economic in Hong Kong. Method We developed Markov model infections using susceptible-infected-recovered structure over 1-year time horizon from Kong healthcare sector perspective measure resource utilization, burden, outcomes. consisted two arms: do nothing implement program. assessed effectiveness units quality-adjusted life years (QALYs) incremental at HKD 1,000,000/QALY threshold. Results program, which reached approximately 72% population with vaccine doses, found have cost 22,339,700 per QALY gained February 2021 2022. At willingness-to-pay threshold, program cost-effective context low prevalence cases before Omicron wave. However, is sensitive infection rate. now experiencing fifth wave Omicron. It estimated that ICER 2022 2023 310,094. Conclusions Vaccination incur large we therefore need acknowledge their limitations short term. This will help relevant departments programs. From longer-term perspective, show great once rates high regional outbreak. Compared other age groups, it suggested elderly should prioritized improve coverage

Language: Английский

Citations

14
A Shot in the Arm for Vaccination Intention: The Media and the Health Belief Model in Three Chinese Societies DOI Open Access
Ruoheng Liu, Yi‐Hui Christine Huang, Jie Sun

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(6), P. 3705 - 3705

Published: March 20, 2022

This large-sample study of three Chinese societies—Mainland China, Taiwan, and Hong Kong—demonstrates the importance media exposure for people’s vaccination intentions during COVID-19 pandemic. By employing two constructs (i.e., perceived susceptibility severity) in health belief model (HBM), identifies significant indirect effects on individuals’ intention all societies. That said, trust negatively moderated path from severity to Mainland China Taiwan. In these societies, higher an individual’s media, less influence his/her intention. It suggests that level is a contextual factor explaining decision-making issues. Generally, combination HBM has been proven be useful understanding intentions. These findings provide practical considerations governmental agencies, public institutions, campaign designers promote

Language: Английский

Citations

13
COVID-19 vaccine hesitancy and influencing factors among Chinese hospital staff: a cross-sectional study DOI Creative Commons
Shangyao Li,

Jinjuan Hao,

Yu Su

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Feb. 22, 2024

Abstract We aimed to investigate the willingness of hospital staff receive COVID-19 vaccine and explore associated factors reasons hesitancy among Chinese staff, which were not yet known. A cross-sectional questionnaire survey was conducted online on in a grade tertiary general Beijing from February 22 23, 2023. Univariate multivariate logistic regression used assess associations between potential influencing hesitancy. total 3269 valid respondents included, rate 32.67%. Multivariate showed that women [1.50 (1.22–1.83)], having high-school education level [1.69 (1.04–2.76)], college degree [2.24 (1.35–3.72)] or graduate [2.31 (1.33–4.03)], underlying disease [1.41 (1.12–1.77)] with higher The main for included doubts safety effectiveness worries adverse reactions. Hospital staff's vaccinate is generally high study. Hospitals should spread knowledge through multiple channels improve cognition encourage vaccination based factors.

Language: Английский

Citations

2
Prevalence and Determinants of COVID-19 Vaccine Acceptance in South East Asia: A Systematic Review and Meta-Analysis of 1,166,275 Respondents DOI Creative Commons
Theo Audi Yanto, Nata Pratama Hardjo Lugito, Lie Rebecca Yen Hwei

et al.

Tropical Medicine and Infectious Disease, Journal Year: 2022, Volume and Issue: 7(11), P. 361 - 361

Published: Nov. 9, 2022

Despite its importance in guiding public health decisions, studies on COVID-19 vaccination acceptance and determinants South East Asia (SEA) are lacking. Therefore, this study aims to determine the prevalence of vaccine variables influencing vaccine’s acceptance. This review is registered under PROSPERO CRD42022352198. We included that reported from all SEA countries, utilising five academic databases (Pubmed, MEDLINE, Cochrane Library, Science Direct, Google Scholar), three Indonesian (the Scientific Journal Database, Neliti, Indonesia One Search), two pre-print (MedRxiv BioRxiv), Thailand (ThaiJo Thai-Journal Citation Index). The analysis was conducted using STATA 17.0 with metaprop commands. for 71% (95%CI 69–74; I2 99.87%, PI: 68.6–73.5). Myanmar achieved highest prevalence, 86% 84–89), followed by Vietnam 82% (95% CI 79–85; 99.04%) Malaysia 78% 72–84; 99.88%). None ten studied (age, sex, education, previous infections, smoking marriage status, insurance, living together, chronic diseases, healthcare workers) were significantly associated result will be useful uptake SEA.

Language: Английский

Citations

9
Vaccine hesitancy and post-vaccination adherence to safety measures: A mixed-method study DOI Creative Commons
Ayesha Inam, Asia Mushtaq,

Sahira Zaman

et al.

Frontiers in Public Health, Journal Year: 2023, Volume and Issue: 11

Published: March 31, 2023

Despite being recognized as one of the most successful public health measures, vaccination is still considered to be unnecessary and unreliable in context COVID-19 pandemic. The current study utilized a two-pronged approach analyzing vaccine hesitancy behaviors after by employing mixed-method design. Phase 1 was aimed at identifying predictors acceptance among Pakistani population using protection motivation theory (PMT), whereas 2 exploring factors related COVID-19.A convenient sample 1,736 individuals from vaccine-eligible (12 years above) selected collect data on (Phase 1). explored post-vaccination behaviors, especially adherence safety measures for COVID-19, through 23 in-depth interviews with vaccinated population.Multiple regression analyses showed that response cost major predictor (in In terms role demographic variables, results male (for severity: B = -0.481; threat appraisal: -0.737), old age (B -0.044), not vaccinated, infected (themselves family members) are strongly associated hesitancy. Results thematic analysis revealed perceived individual experience insensitivity toward severity disease lack COVID-19. Faith religious beliefs reliance traditional remedies also key people's general non-compliance behaviors. One interesting aspect financially socially destabilized situation developing countries contributed apathy pandemic situation.The findings may help devising model world deal future situations.

Language: Английский

Citations

5