Research Square (Research Square),
Journal Year:
2023,
Volume and Issue:
unknown
Published: March 10, 2023
Abstract
objective:
Social
residents
become
increasingly
concerned
about
Alzheimer's
dementia
(AD)
as
a
global
public
health
crisis.
China's
AD
population
is
the
largest
and
growing
fastest.
However,
no
study
has
examined
Chinese
social
residents'
knowledge
attitudes
concerning
illness.
This
using
ADKS
DAS.
Study
design:
Cross-sectional
survey.
338
over
18
from
various
regions
were
recruited
convenient
sampling.
Method:
The
Disease
Knowledge
Scale
(Chinese)
Dementia
Attitude
used
to
assess
their
attitude
regarding
AD.
Results:
A
total
of
328
respondents
(97.04%)
completed
=
19.44±3.33;
DAS
86.98±12.7.
Age
education
level
can
have
substantial
impact
on
scores,
scores.
Conclusion:
Low
levels
awareness
acceptance
exist
among
residents.
results
indicate
that
China
must
immediately
implement
comprehensive
for
its
General Psychiatry,
Journal Year:
2023,
Volume and Issue:
36(3), P. e101054 - e101054
Published: June 1, 2023
Due
to
the
inaccuracy
of
traditional
geographical
distance-based
definition
left-behind
status,
data
on
negative
effect
status
cognitive
function
among
older
adults
are
controversial.This
study
examined
cross-sectional
and
longitudinal
associations
with
in
Chinese
adults.
The
was
based
frequency
face-to-face
parent-child
meetings.Data
from
a
nationally
representative
sample
8
682
(60+
years)
2015
(5
658
left
behind
3
024
non-left
behind),
which
6
933
completed
follow-up
2018,
were
obtained
China
Health
Retirement
Longitudinal
Study.
Left-behind
broadly
defined
as
those
aged
60+
years
who
had
living
adult
children
saw
their
less
than
once
per
month.
assessed
composite
test
higher
total
scores
indicating
better
function.Left-behind
significantly
lower
non-left-behind
both
(11.1
(6.0)
vs
13.2
(5.9),
t=15.863,
p<0.001)
2018
(10.0
(6.6)
12.4
(6.7),
t=14.177,
p<0.001).
After
adjusting
for
demographic
factors,
lifestyle
chronic
medical
conditions
baseline
score
(in
analysis
only),
average,
0.628
counterparts
(t=5.689,
This
difference
attenuated
0.322
but
remained
significant
(t=2.733,
p=0.006).Left-behind
have
risk
poor
decline
counterparts.
Specific
efforts
targeting
adults,
such
encouraging
visit
parents
more
regularly,
warranted
maintain
or
delay
progression
decline.
The Journal of Prevention of Alzheimer s Disease,
Journal Year:
2025,
Volume and Issue:
12(2), P. 100041 - 100041
Published: Jan. 23, 2025
The
associations
of
early-onset
coronary
heart
disease
(CHD)
and
genetic
susceptibility
with
incident
dementia
brain
white
matter
hyperintensity
(WMH)
remain
unclear.
Elucidation
this
problem
could
promote
understanding
the
neurocognitive
impact
CHD
provide
suggestions
for
prevention
dementia.
This
study
aimed
to
investigate
whether
observed
genetically
predicted
were
related
subsequent
WMH
volume.
Prospective
cohort
study.
UK
Biobank.
500
671
individuals
without
at
baseline.
Early-onset
(male
≤55
years;
female
≤65
years)
was
ascertained
using
hospital
inpatient
records.
Incident
including
all-cause
dementia,
Alzheimer's
disease,
vascular
records,
mortality
register
data,
self-reported
data.
volume
measured
through
magnetic
resonance
imaging
(MRI).
Cox
proportional
hazards
models
linear
regression
used
analyze
WMH.
Subsequently,
a
polygenetic
risk
score
(PRS)
analysis
conducted
outcomes.
Among
(female:
272
669,
54.5%;
mean
age:
57.0
±
8.1
years),
9
294
occurred
during
median
follow-up
13.8
years.
Compared
non-CHD
group,
both
(n
=
16
133)
late-onset
43
944)
groups
had
higher
risks
developing
(hazard
ratio
[HR]:
1.99,
95%
confidence
interval
[CI]:
1.81
2.19
group;
HR:
1.20,
CI:
1.14
1.27
group).
participants,
associated
significantly
compared
(HR:
1.56,
1.39
1.75).
In
subset
40
290
who
completed
MRI
scans
9.3
years,
participants
exhibited
largest
among
three
(early-onset
CHD,
non-CHD,
Ptrend<0.001).
PRS
supported
(odds
[OR]
highest
quartile:
1.37,
1.28
1.46,
Ptrend<0.001)
(β
0.042,
0.017
0.068,
Ptrend=0.002).
are
larger
Additional
attention
should
be
paid
status
CHD.
Alzheimer s & Dementia Translational Research & Clinical Interventions,
Journal Year:
2025,
Volume and Issue:
11(1)
Published: Jan. 1, 2025
Abstract
The
rising
age
of
the
global
population
has
made
Alzheimer's
disease
and
related
dementias
(ADRD)
a
critical
public
health
problem,
with
significant
health‐related
disparities
observed
between
rural
urban
areas.
However,
no
previous
reviews
have
examined
scope
determinant
factors
contributing
to
rural–urban
ADRD‐related
outcomes.
This
study
aims
systematically
collate
synthesize
peer‐reviewed
articles
on
in
ADRD,
identifying
key
determinants
research
gaps
guide
future
research.
We
conducted
systematic
search
using
terms
ADRD
without
restrictions
geography
or
design.
Five
engines—MEDLINE,
CINAHL,
Web
Science,
PubMed,
Scopus—were
used
identify
relevant
articles.
was
performed
August
16,
2024,
included
English‐language
published
from
2000
onward.
Sixty‐three
met
eligibility
criteria
for
data
extraction
synthesis.
Most
were
after
2010
(85.7%)
concentrated
United
States,
China,
Canada
(66.7%).
A
majority
had
cross‐sectional
(58.7%)
cohort
designs
(23.8%),
primarily
examining
prevalence
(41.3%)
incidence
(11.1%).
Findings
often
indicated
higher
areas,
although
inconsistent
classification
systems
noted.
Common
risk
female
sex,
lower
education
level,
income,
comorbidities
such
as
diabetes
cerebrovascular
diseases.
Environmental
(12.7%)
lifestyle
(14.3%)
been
less
explored.
statistical
methods
mainly
traditional
analyses
(e.g.,
logistic
regression)
lacked
advanced
techniques
machine
learning
causal
inference
methods.
identified
this
review
emphasize
need
underexplored
geographic
regions
encourage
use
investigate
understudied
disparities,
environmental,
lifestyle,
genetic
influences.
Highlights
Few
studies
focus
low‐
middle‐income
countries.
include
low
attainment,
comorbidities.
Inconsistent
definitions
“rural”
complicate
cross‐country
comparisons.
affecting
are
underexplored.
Advanced
methods,
inference,
recommended.
Journal of Global Health,
Journal Year:
2024,
Volume and Issue:
14
Published: Nov. 8, 2024
Dementia
and
cognitive
impairment
rates
in
Asia
have
significant
policy
implications.
Contrary
to
the
existing
literature,
which
primarily
focused
on
Western
region,
this
study,
we
provide
novel
insights
into
previously
unexplored
geographical
contexts.
We
aimed
evaluate
prevalence
of
dementia
Asia.
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(11), P. e31918 - e31918
Published: May 24, 2024
Primary
medical
workers
constitute
a
high-risk
group
for
mental
health
problems,
and
psychological
resilience
might
protect
them
from
the
negative
impacts
of
their
work.
Therefore,
this
study
aimed
to
investigate
current
situation
among
primary
care
in
Wuhan,
China,
as
well
related
factors.
Public Health Nursing,
Journal Year:
2024,
Volume and Issue:
41(5), P. 943 - 950
Published: July 1, 2024
Social
residents
become
increasingly
concerned
about
Alzheimer's
dementia
(AD)
as
a
global
public
health
crisis.
China's
AD
population
is
the
largest
and
growing
fastest.
However,
no
study
has
examined
Chinese
social
residents'
knowledge
attitudes
concerning
illness.
This
using
Disease
Knowledge
Scale
(ADKS)
scale
(DAS).
Geriatrics,
Journal Year:
2024,
Volume and Issue:
9(6), P. 149 - 149
Published: Nov. 13, 2024
Background/Objectives:
A
significant
proportion
of
older
adults
with
Alzheimer’s
disease
or
related
disorders
live
in
a
long-term
care
facility.
This
study
aimed
to
determine
the
time
delay
between
admission
and
death
for
dementia.
Methods:
post
hoc
analysis
was
conducted
using
data
from
French
observational
cohort,
identifying
dementia
who
were
admitted
nursing
homes.
assessed
median
survival
times
after
facilities
by
Kaplan–Meier
models
evaluated
factors
potentially
associated
until
Cox
models.
Results:
total
201
individuals
included.
The
home
39
months.
Being
male,
an
age,
having
higher
cognitive
impairment
comorbidities
decreased
rates.
Conclusions:
provides
results
institutionalised
France
elements
definition
future
public
policies.
Journal of Alzheimer s Disease,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 26, 2024
Background
The
continuously
increasing
aging
population
and
life
expectancy
have
led
to
an
inconsistent
underestimated
dementia
prevalence
in
China.
An
updated
epidemiologic
study
is
urgently
needed.
Objective
To
update
the
rate
risk
factors
of
Methods
For
this
national
cross-sectional
study,
20,438
participants
aged
≥65
from
28
communities
56
villages
14
centers
were
recruited
using
a
multistage
cluster
sampling
design
between
May
2019
December
2019.
Participants
assessed
with
series
clinical
neuropsychological
measurements.
rates
dementia,
Alzheimer's
disease
(AD),
vascular
(VaD),
as
well
factors,
calculated
multivariate-adjusted
models.
Results
crude
9.1%
(95%
CI,
8.7%–9.5%)
for
6.0%
5.7%–6.3%)
AD,
1.4%
1.2%–1.5%)
VaD,
1.8%
1.6%–2.0%)
other
dementias
years.
overall
sex-
age-standardized
was
8.8%.
Apart
AD
higher
females
than
males
(10.3%
versus
7.7%,
respectively).
Moreover,
increased
significantly
age.
Being
unmarried
having
fewer
social
activities
risks
main
subtypes.
Risk
not
exactly
same
VaD.
Conclusions
almost
comparable
that
developed
countries
individuals
These
findings
may
serve
new
evidence
government
interventions
aging.
Frontiers in Psychiatry,
Journal Year:
2024,
Volume and Issue:
15
Published: Dec. 19, 2024
Individuals
with
both
type
2
diabetes
mellitus
(T2DM)
and
hypertension
have
an
increased
risk
of
cognitive
impairment
(CI)
compared
to
those
either
T2DM
or
hypertension.
Therefore,
this
study
aims
identify
the
prevalence
CI
its
associated
factors
in
patients
Hunan,
China.
