Global COVID-19 vaccine acceptance level and its determinants: an umbrella review

BMC Public Health, Journal Year: 2024, Volume and Issue: 24(1)

Published: Jan. 2, 2024

Abstract Background The COVID-19 vaccination is essential for reducing disease burden on a worldwide scale. success of this strategy will largely depend how well vaccines are received. Previous reviews had produced contradictory results, and there been no umbrella review. Therefore, the objective review was to combine data regarding vaccination’s global acceptance rate its contributing factors. Methods Using PRISMA guideline, PubMed, Embase, Scopus, Web Sciences, Cochrane Database Systematic Reviews, Scopus Google Scholar which reported vaccine and/or determinants were searched. quality included studies assessed using Assessment Multiple Reviews (AMSTAR). A weighted inverse variance random-effects model applied find pooled estimates. subgroup analysis, heterogeneity, publication bias sensitivity analysis also assessed. Result Twenty-two SRM with 10,433,306 study participants included. globally found be 60.23 (95% CI: 58.27, 62.18). In low-income countries, level 54.07(50.31, 57.83) while magnitude 64.32 (62.24,66.40) among across globe. Higher education (AOR =1.96; 95% CI:1.20, 2.73), good knowledge (2.20; CI:1.36, 3.03), favourable attitude =4.50; CI:2.89, 6.12), previous history infection =3.41; CI:1.77, 5.06), male sex =1.62; CI:1.47, 1.77), chronic =1.54; CI:1.18, 1.90) predictors acceptance. Conclusion highly varied unacceptably low particularly in countries. education, knowledge, attitude, COVID-19, sex, factors rate. collaborative effort stakeholders such as policymakers, campaign program planners needed improve vaccine.

Language: Английский

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COVID-19 Vaccine Hesitancy: Umbrella Review of Systematic Reviews and Meta-Analysis

JMIR Public Health and Surveillance, Journal Year: 2024, Volume and Issue: 10, P. e54769 - e54769

Published: April 30, 2024

The unprecedented emergence of the COVID-19 pandemic necessitated development and global distribution vaccines, making understanding vaccine acceptance hesitancy crucial to overcoming barriers vaccination achieving widespread immunization.

Language: Английский

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COVID-19 vaccine acceptance and hesitancy in Cameroon: a systematic review and meta-analysis

BMC Public Health, Journal Year: 2025, Volume and Issue: 25(1)

Published: March 17, 2025

The development of effective vaccines was a promising tool for ending the pandemic. However, success vaccination programme hinges on achieving substantial community acceptance. In Cameroon, numerous studies have investigated level acceptance, hesitancy, and perception COVID-19 vaccines, with mixed results. To provide comprehensive understanding these parameters, this meta-analysis aimed to estimate pooled proportion vaccine hesitancy in Cameroon. A systematic search online databases, including PubMed, Google Scholar, ScienceDirect, conducted identify relevant research articles. This study adhered Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines. extracted data were compiled Microsoft Excel spreadsheet analyzed using R statistical software (version 4.3.3). calculated random-effects meta-analysis. Funnel plots, Egger's, Begg's tests used assess publication bias. Of 1,346 records identified through database search, 20 articles included review model showed that approximately 31.21% (95% CI: 23.49–38.94) participants willing accept vaccine. More than two-thirds population (68.49%; 95% 60.65–76.34) hesitant. Half (51.81%; 42.70-60.93), had negative acceptance rate progressed from first semester 2021 (27.21%; 10.38–44.05) 2022 (45.56%; 25.00-66.12). 29.29% 19.86–38.72) general 39.24% 22.84–55.64) healthcare workers. 70.39% 61.30–79.80) 57.42% 4.05–71.80) Although progress targeted interventions remain necessary address country. Strategies such as enhancing access accurate information, fostering trust institutions, strengthening engagement crucial increasing uptake.

Language: Английский

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The pervasive association between political ideology and COVID-19 vaccine uptake in Brazil: an ecologic study

BMC Public Health, Journal Year: 2023, Volume and Issue: 23(1)

Published: Aug. 23, 2023

Despite the unequivocal benefits of vaccination, vaccine coverage has been falling in several countries past few years. Studies suggest that hesitancy is an increasingly significant phenomenon affecting adherence to vaccines. More recently, during COVID-19 pandemic, political views have emerged as additional influencing factor for hesitancy.In this ecologic study, we used information from publicly available databases investigate association between ideology, depicted by percentage votes right-wing candidate Jair Bolsonaro presidential elections 2018 and 2022, vaccination Brazilian municipalities. The primary endpoint was index, calculated number doses administered up September 2022 divided inhabitants each municipality. analysis conducted using Pearson correlation coefficients linear regression models adjusted HDI, male voters, voters who were older than 50 years old, with a middle school education or less. In addition, explored whether effect on index modified different quartiles HDI interaction term.Five thousand five hundred sixty-three municipalities included analysis. For both elections, significantly inversely associated uptake after adjustment sociodemographic characteristics (change mean 1% increase -0.11, 95% confidence interval [CI] -0.13 -0.08, p < 0.001; change -0.09, CI -0.11 -0.07, 0.001). We also found statistically predictor interest scores, more detrimental stance lower (interaction 0.001 first quartile; = second quartile).Our findings ideologies influenced municipalities, communities inequitably. politicization vaccines new challenge programs. Strategies face these challenges should include joint efforts governments civil society common public health goal.

Language: Английский

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COVID‐19 vaccine acceptance among people living with HIV: A systematic review and meta‐analysis

Tropical Medicine & International Health, Journal Year: 2023, Volume and Issue: 28(8), P. 601 - 611

Published: July 4, 2023

Abstract Objective To assess coronavirus disease 2019 (COVID‐19) vaccine acceptance among people living with HIV (PLHIV) worldwide. Methods We searched MEDLINE, PSYINFO, CINHAL, Scopus and EMBASE databases other sources including free Google search subject‐specific journals from January 2020 to September 2021. The study population included adults (aged 18+ years) evaluated for COVID‐19 acceptance. A random effect meta‐analysis model was used estimate the pooled rate. Subgroup analyses were performed, factors associated hesitancy underwent narrative analysis. Of 558 initial records, 14 studies eligible review. Results overall rate adult PLHIV 62% (95% confidence interval [CI], 56%–69%). In subgroup analysis, estimated higher in high‐income countries: 63% CI, 55%–70%) versus 54%–71%) low‐ middle‐income countries, conducted 2022 (66% [95% 58%–75%]) than 2021 (57% 47%–68%]). Reasons lower monthly income, being non‐homosexual, history of chronic disease, COVID‐19‐related medical mistrust, not knowing anyone who died COVID‐19, believing oneself be immune general refusal, negative attitude vaccine, concerns about efficacy, safety side effects, distrust common vaccine‐related information using social media as a source on COVID‐19. Conclusion Among PLHIV, is generally low. greater emphasis collaborative efforts between all concerned bodies needed boost this population.

Language: Английский

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Determinants of COVID‐19 Vaccination Status and Vaccine Hesitancy in the Centre‐Est Region of Burkina Faso: A Population‐Based Cross‐Sectional Study

Advances in Public Health, Journal Year: 2025, Volume and Issue: 2025(1)

Published: Jan. 1, 2025

Background: Many countries, such as Burkina Faso, have implemented coronavirus disease 2019 (COVID‐19) vaccination campaigns to control the pandemic. Understanding vaccination‐related behavior, particularly in rural areas, might help address this goal by increasing vaccine coverage. Our study aimed evaluate COVID‐19 status and hesitancy rate identify their associated factors among population of Centre‐Est Region Faso. Methods: A population‐based cross‐sectional was conducted Region, which is one 13 regions random three‐stage sampling design used select participants household between March 19 31, 2022. To with hesitancy, we performed a modified Poisson regression. Results: total 1199 were included study. Females represented 52.1% sample, mean age 37.5 years, standard deviation 15.83 years. The majority (95.7%) had already heard vaccination. Radio main source information (35.8%) about 41.7% (95% confidence interval [CI]: 38.9–44.4). determinants being male, married, living having good knowledge prevention measures. Among unvaccinated individuals, 65.7% CI: 62.1–69.1). With 79.5%, fear side effects reason for hesitancy. lower areas resident (adjusted prevalence ratio [aPR]: 0.82 [95% 0.72–0.94]), female (aPR: 0.86 0.74–0.99]), measures 0.87 0.78–0.97]), farmer. Conclusion: revealed higher Improving communication preventive increase adherence

Language: Английский

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COVID- 19 vaccine uptake and its determinants in Cameroon: a systematic review and meta-analysis (2021–2024)

BMC Infectious Diseases, Journal Year: 2025, Volume and Issue: 25(1)

Published: April 15, 2025

COVID-19 vaccination is crucial for mitigating the pandemic's impact. However, vaccine hesitancy and access challenges have hindered global efforts. This meta-analysis aimed to estimate pooled uptake proportion identify associated determinants in Cameroon. review, conducted according Preferred Reporting Items Systematic Reviews Meta-Analyses (PRISMA) guidelines, identified articles through searches of electronic databases, including PubMed, ScienceDirect, Google Scholar, as well gray literature. The search encompassed published unpublished studies from 2021 2024 reporting on and/or acceptance Extracted data were compiled a Microsoft Excel spreadsheet analyzed using R statistical software (version 4.4.2). A random-effects model was employed when heterogeneity exceeded 50%. Publication bias assessed funnel plots, Egger's Begg's tests. Meta-regression used explore influence study characteristics. Twenty-two studies, encompassing 24,130 participants, included. 37.14% (95% CI: 29.24-45.05) with substantial (I2 = 98.2%, p < 0.001). Subgroup analyses revealed lower among general population (23.18%; 95% 10.11-36.25) community settings (16.0%; 0.97-31.04) compared healthcare workers (42.12%; 34.14-50.09). Younger age (OR 0.53; 0.42-0.67) inversely uptake, while being partnership 1.59; 1.11-2.27) positively associated. Higher levels education 1.75; 1.56-1.97), urban residence 1.66; 1.21-2.29) acceptance. suboptimal required ensure herd immunity. results this underline need step up efforts improve coverage, particularly most vulnerable populations. Identifying addressing factors underlying low coverage imperative if public health objectives are be met. Public interventions should tailored address specific concerns needs different groups marital statuses.

Language: Английский

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Exploring Determinants of COVID-19 Vaccine Acceptance, Uptake, and Hesitancy in the Pediatric Population: A Study of Parents and Caregivers in Saudi Arabia during the Initial Vaccination Phase

Healthcare, Journal Year: 2023, Volume and Issue: 11(7), P. 972 - 972

Published: March 29, 2023

Objectives: This study aims to assess COVID-19 vaccine acceptance, uptake, and hesitancy among parents caregivers of children in Saudi Arabia during the initial rollout pediatric vaccination. Methods: An electronic survey was used collect data from participants who visited a center. The included demographic data, status their children, reasons for acceptance or rejection. Vaccine Hesitancy Scale (VHS) tool also employed attitudes toward routine childhood Multivariate binary regression analysis identify predictors actual uptake children. Results: Of 873 respondents analysis, 61.5% were 38.5% other caregivers. participants, 96.9% had received vaccine. Six hundred ninety-four accepted with main being an endorsement by Ministry Health (60%) importance going back school (55%). One seventy-nine would not vaccinate most common fear adverse effects (49%) inadequate about safety (48%). Factors such as age, vaccination status, self-rated family commitment level, children’s vaccines, participants’ generalized anxiety disorder (GAD7) score did significantly correlate status. Parents less likely compared caregivers, higher socioeconomic more Conclusion: high Arabia. Still, ongoing healthcare authorities should continue advocate better

Language: Английский

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Quantitative Synthesis of Factors Associated with COVID-19 Vaccine Acceptance and Vaccine Hesitancy in 185 Countries

Vaccines, Journal Year: 2023, Volume and Issue: 12(1), P. 34 - 34

Published: Dec. 28, 2023

Mass vaccination against COVID-19 is the best method to ensure herd immunity in order curb effect of pandemic on global economy. It therefore important assess determinants vaccine acceptance and hesitancy a scale. Factors were recorded from cross-sectional studies analyzed with t-Test, ANOVA, correlation, meta-regression analyses synthesized identify trends inform policy. We registered protocol (ID: CRD42022350418) used standard Cochrane methods PRISMA guidelines collect synthesize articles published between January 2020 August 2023. A total 67 576 185 countries involving 3081,766 participants included this synthesis. Global was 65.27% (95% CI; 62.72–67.84%), while stood at 32.1% 29.05–35.17%). One-Way ANOVA showed that there no significant difference percentage Gross Domestic Product spent procurement across World Bank income levels (p < 0.187). There 0.001) 0.005) different Income levels. level had strong influence 0.0004) 0.003) but did not. correlation (r = −0.11, p 0.164) or −0.09, 0.234). Meta-regression analysis living an urban setting (OR 4.83, 95% 0.67–212.8), rural 2.53, 0.29–119.33), older 1.98, 0.99–4.07), higher education 1.76, 0.85–3.81), being low earner 2.85, 0.45–30.63) increased odds high acceptance. influenza 33.06, 5.03–1395.01), mistrust for vaccines 3.91, 1.92–8.24), complacency 2.86, 1.02–8.83), pregnancy 2.3, 0.12–141.76), taking traditional herbs 2.15, 0.52–10.42), female 1.53, 0.78–3.01), safety concerns 1.29, 0.67–2.51). proposed number recommendations increase COVID-19.

Language: Английский

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Uptake of COVID-19 vaccine among high-risk urban populations in Southern Thailand using the COM-B model

PLoS ONE, Journal Year: 2024, Volume and Issue: 19(3), P. e0300509 - e0300509

Published: March 14, 2024

Background The COVID-19 pandemic has imposed unprecedented suffering on social and individual levels worldwide. Vaccines against have been prioritized as a crucial strategy for ending the well minimizing its consequences. Objectives This study aimed to determine uptake of vaccine among high-risk urban populations in Southern Thailand using Capability, Opportunity, Motivation, Behavior (COM-B) model. Methods We conducted web-based cross-sectional Hat Yai district, Songkhla province Thailand, September October 2021. questionnaire was composed sections sociodemographic characteristics, vaccination status, COM-B constructs. employed multivariable logistic regression analysis factors associated with vaccine. set statistical significance at p < 0 . 05 Results In this study, females constituted 54.7% total participants (n = 358), nearly half (45.8%) were younger age group (18–29). Of all participants, 59.5% (95%CI: 54.2%-64.6%) received least one dose Factors their adjusted OR (95% CI) being married: 3.59 (2.06–6.24), having graduate degree: 2.34 (1.38–3.96), gainfully employed: 3.30 (1.91–5.67), high level opportunity: 2.90 (1.48–5.66), motivation: 2.87 (1.17–17.08). Conclusion vaccines moderate population. Moreover, results showed that model is useful predicting uptake. findings could be used aid future public health interventions any event outbreaks similar disease beyond.

Language: Английский

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