Scholars International Journal of Obstetrics and Gynecology,
Journal Year:
2023,
Volume and Issue:
6(10), P. 378 - 387
Published: Oct. 11, 2023
Polycystic
ovarian
syndrome
is
a
common
cause
of
dysfunction
in
women
with
anovulation
world
wide.50-70%
patients
PCOS
exhibit
metabolic
abnormalities,
including
poor
glucose
tolerance
and
hyperinsulinemia.
The
prevalence
vitamin
D
deficiency
about
67-85
per
cent,
serum
concentrations
25(OH)
<20
ng/ml.
It
suggested
that
there
an
association
between
levels
parameters
PCOS,
fasting
levels,
insulin,
insulin
resistance,
high
blood
pressure,
lipid
disorders,
obesity,
fertility
other
clinical
laboratory-
related
associated
PCOS.
Given
the
south
Indian
population,
less
number
studies,
inconclusive
especially
population
as
well
evidence
from
recent
studies
indicating
link
lab
parameters,
this
study
aimed
to
assess
relationship
resistance
Pearsons
correlation
showed
0.034
HOMA
IR
d
more
values,
resistance.
0.05
No
significant
relation
seen
(Pearsons
value
>0.05).
In
study,
it
was
found
percentage
were
deficient.
also
difference
values
some
such
waist
circumference,
HOMA-IR,
BMI
without
deficiency;
however,
no
linear
baseline
variables,
except
for
BMI,
G120.
conclusion,
our
data
confirm
Insulin
Thus,
supplementation
could
be
beneficial
treatment
abolish
regulate
menstrual
irregularities.
Gynecological Endocrinology,
Journal Year:
2024,
Volume and Issue:
40(1)
Published: March 2, 2024
Background
Polycystic
Ovary
Syndrome
(PCOS)
is
the
most
frequent
endocrine
disorder
in
female
adults,
and
hyperandrogenism
(HA)
typical
feature
of
PCOS.
This
study
aims
to
investigate
trends
hotspots
PCOS
HA.
Methodology:
Researchers
at
Nishter
Hospital
in
Multan
analysed
data
from
100
pregnant
women
who
were
enrolled
their
antenatal
care
between
the
ages
of
20
and
45.
Fifty
diagnosed
with
PCOS,
while
another
50
served
as
controls.
Patients'
demographic,
clinical,
menstrual,
pregnancy
information
was
documented.
We
monitored
maternal
outcomes
such
spontaneous
abortion,
GDM,
preterm
birth,
PIH
enrollment
till
delivery
all
patients
(PIH).
SPSS
Statistics
20.0
programme
that
used
for
statistical
analysis.
RESULTS:
The
majority
participants
(59%)
30.
percentage
PCOS
had
a
high
body
mass
index
(BMI)
significantly
higher
than
control
group,
which
38
percent.
GDM
occurred
10(20%)
7(14%)
cases
without
p-value=0.42,
11(22%)
whereas
controls
it
9(18%),
p-value=0.62,
birth
i.e.
13(26%)
6(12%),
p-value=0.07),
Spontaneous
abortions
(SAB)
5(10%)
2(4%)
vaginal
37(74%)
where
21(42%),
cesarean
recorded
24(48%)
p-value=0.005.
Conclusion:
complications
include
SAB,
premature
group.
Moreover,
these
pregnancies
are
high-risk
outcome
require
frequent
prenatal
care.
Keywords:
outcome,
South Asian Research Journal of Pharmaceutical Sciences,
Journal Year:
2023,
Volume and Issue:
5(03), P. 87 - 95
Published: June 14, 2023
Background:
Polycystic
ovary
syndrome
(PCOS)
is
a
widespread
complex
endocrine
disorder
of
women
in
the
reproductive
age
group.
Plasminogen
activator
inhibitor-1(PAI-1)
has
been
shown
to
be
associated
with
regulation
inflammation
and
ovulation.
Objectives:
The
aim
this
study
was
evaluate
serum
PAI-1
level
determine
effects
metformin
treatment
on
levels
patients
PCOS.
Patients
Methods:
This
conducted
sixty
PCOS,
while
30
healthy
matched
for
PCOS
were
selected
as
control
group,
only
them
complete
follow
up
they
agree
continue
during
three
months,
duration
up.
Study
Design:
A
cross
sectional
done
Salah
Al-Deen
general
hospital/gynecology
obstetrics
department
Tikrit
city
from
1st
November
2022-30th
January
2023.
diagnosed
PCOs
depending
based
Rotterdam
criteria.
Participants
enrolled
after
all
eligibility
criteria
confirmed
informed
consent
completed.
body
mass
index
determined
before
therapy.
Homeostatic
model
assessment
insulin
resistance
according
following
formula:
(fasting
multiplied
by
fasting
glucose)
divided
405.
Fasting
measured
Enzyme-Linked
Immunosorbent
Assay
method.
Data
analyzed
using
SPSS
Windows
7.
Results:
Compared
PAI1,
blood
glucose
(FBG),
Insulin,
homeostasis
(HOMA-IR)
While
follicle
stimulating
hormone
(FSH)
significantly
decreased
(P<0.05).
In
group
increased
Serum
testosterone
treated
showed
significant
decrease
concentration
at
p-values
0.05,
when
compared
pre-treatment.
Treatment
resulted
index,
Blood
glucose,
HOMA-IR,
LH
0.05.
Conclusion:
inhibitor-1
3
months
850
mg
per
day
Scholars International Journal of Obstetrics and Gynecology,
Journal Year:
2023,
Volume and Issue:
6(10), P. 378 - 387
Published: Oct. 11, 2023
Polycystic
ovarian
syndrome
is
a
common
cause
of
dysfunction
in
women
with
anovulation
world
wide.50-70%
patients
PCOS
exhibit
metabolic
abnormalities,
including
poor
glucose
tolerance
and
hyperinsulinemia.
The
prevalence
vitamin
D
deficiency
about
67-85
per
cent,
serum
concentrations
25(OH)
<20
ng/ml.
It
suggested
that
there
an
association
between
levels
parameters
PCOS,
fasting
levels,
insulin,
insulin
resistance,
high
blood
pressure,
lipid
disorders,
obesity,
fertility
other
clinical
laboratory-
related
associated
PCOS.
Given
the
south
Indian
population,
less
number
studies,
inconclusive
especially
population
as
well
evidence
from
recent
studies
indicating
link
lab
parameters,
this
study
aimed
to
assess
relationship
resistance
Pearsons
correlation
showed
0.034
HOMA
IR
d
more
values,
resistance.
0.05
No
significant
relation
seen
(Pearsons
value
>0.05).
In
study,
it
was
found
percentage
were
deficient.
also
difference
values
some
such
waist
circumference,
HOMA-IR,
BMI
without
deficiency;
however,
no
linear
baseline
variables,
except
for
BMI,
G120.
conclusion,
our
data
confirm
Insulin
Thus,
supplementation
could
be
beneficial
treatment
abolish
regulate
menstrual
irregularities.
