Psychological distress after COVID-19 recovery and subsequent prolonged post-acute sequelae of COVID-19: A longitudinal study with 1-year follow-up in Japan

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: March 24, 2024

Abstract Background This study investigated the longitudinal association between psychological distress in post-acute phase and subsequent prolonged sequelae of COVID-19 (PASC) among individuals with PASC. Methods An online survey 1-year interval was conducted from July to September 2021 (T1) 2022 (T2). Individuals who were 20-years-old or older, had a positive Polymerase Chain Reaction test, one month post-infection, did not select “Nothing” question regarding PASC presence included. The primary outcome at T2. general, respiratory, muscular, neurological, gastrointestinal, dermatological, cardiac symptoms T2 also used as an patients relevant time 1 (T1). Exposure measured using Kessler scale (K6) T1, those whose K6 13 higher identified having distress. Marginal structure models robust standard errors examine T1 any T2, associations each symptom participants T1. Results A total 1674 analyzed; 17%had ; In total, 818 (48.9%), 523 (31.2%), 672 (40.1%) reported neurological respectively. odds (Odds Ratio [OR] =1.81, 95% Confidence Interval [CI]= 1.08 – 3.03) general respiratory (OR = 1.95, CI 1.02 3.76; OR 2.44, 1.03 5.80). Conclusion Psychological may lead symptoms, mainly follow-up Key Messages before infection during acute predicts Post-Acute Sequelae (PASC); however, PASC, it is unclear whether indicated that led levels especially follow-up. Therefore, mental health care for help improve mitigate

Language: Английский

Unmasking the long-term effects: unravelling neuropsychiatric and neurological consequences of COVID-19

Annals of Medicine and Surgery, Journal Year: 2024, Volume and Issue: 86(3), P. 1490 - 1495

Published: Jan. 4, 2024

The COVID-19 pandemic has not only burdened healthcare systems but also led to a new emerging medical enigma that is post-COVID-19 syndrome or “long COVID.” Characterized by persistent symptoms extend beyond the acute phase of illness, long COVID rapidly become public health concern with ambiguous neurological and neuropsychiatric dimensions. This narrative review aims at synthesizing available research decode long-term impacts on mental health. Drawing from multitude studies, this synthesizes evidence various symptoms, including cognitive deficits, mood disorders, more. delves into potential pathogenic mechanisms, hoping fill existing gaps offering directions for future inquiry. objective just academic; it immediate real-world implications. Understanding these effects crucial developing effective treatments interventions, thereby better serving millions individuals living lingering symptoms. As continue grapple fallout pandemic, provides much-needed context insights an area demands urgent action.

Language: Английский