Pathophysiological, Neuropsychological, and Psychosocial Influences on Neurological and Neuropsychiatric Symptoms of Post-Acute COVID-19 Syndrome: Impacts on Recovery and Symptom Persistence DOI Creative Commons

Alex Malioukis,

R Sterling Snead, Julia Marczika

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2831 - 2831

Published: Dec. 13, 2024

Although the impact of post-acute COVID-19 syndrome (PACS) on patients and public health is undeniably significant, its etiology remains largely unclear. Much research has been conducted pathophysiology, shedding light various aspects; however, due to multitude symptoms clinical conditions that directly or indirectly define PACS, it challenging establish definitive causations. In this exploration, through systematically reviewing latest pathophysiological findings related neurological syndrome, we aim examine how psychosocial neuropsychological may overlap with ones, they not only serve as risk factors but also contribute persistence some primary disorder. Findings from our synthesis suggest psychological factors, such anxiety, depression, loneliness, interact in a self-reinforcing feedback loop. This cycle seems be affecting both physical distress, potentially increasing severity PACS symptoms. By pointing out interaction, review study, attempt offer new perspective interconnected nature psychological, psychosocial, emphasizing importance integrated treatment approaches disrupt improve outcomes when possible.

Language: Английский

Frailty as a Risk Factor for Depression after COVID-19 Hospital Admission DOI Creative Commons

Isabel Soler-Moratalla,

Sergio Salmerón Ríos,

Silvia Lozoya-Moreno

et al.

Geriatrics, Journal Year: 2024, Volume and Issue: 9(4), P. 97 - 97

Published: July 22, 2024

Background: This work aims to establish the relationship between depression and epidemiological or imaging variables, frailty, cognitive status in patients who suffered hospital admission for COVID-19. Methods: A longitudinal observational study investigated 72 admitted COVID-19 a Spain. Patients were evaluated at discharge six months later. Clinical, analytical, variables collected. neurocognitive, nutritional, frailty (FRAIL scale) assessment of included was carried out. The risk considered result above 5 points on PHQ-9 scale. Results: that significantly related 6 after (p = 0.006 pre-frail p 0.001 frail), small-vessel vascular disease tests 0.033), vitamin D level 0.006), taking antidepressants 0.011). Factors negatively associated with presence higher score CAMCOG scale 0.041) older age 0.006). Conclusions: Frailty worsened required SARS-CoV-2 infection. It is important implement prevention measures both these patients.

Language: Английский

Citations

1
Pathophysiological, Neuropsychological, and Psychosocial Influences on Neurological and Neuropsychiatric Symptoms of Post-Acute COVID-19 Syndrome: Impacts on Recovery and Symptom Persistence DOI Creative Commons

Alex Malioukis,

R Sterling Snead, Julia Marczika

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(12), P. 2831 - 2831

Published: Dec. 13, 2024

Although the impact of post-acute COVID-19 syndrome (PACS) on patients and public health is undeniably significant, its etiology remains largely unclear. Much research has been conducted pathophysiology, shedding light various aspects; however, due to multitude symptoms clinical conditions that directly or indirectly define PACS, it challenging establish definitive causations. In this exploration, through systematically reviewing latest pathophysiological findings related neurological syndrome, we aim examine how psychosocial neuropsychological may overlap with ones, they not only serve as risk factors but also contribute persistence some primary disorder. Findings from our synthesis suggest psychological factors, such anxiety, depression, loneliness, interact in a self-reinforcing feedback loop. This cycle seems be affecting both physical distress, potentially increasing severity PACS symptoms. By pointing out interaction, review study, attempt offer new perspective interconnected nature psychological, psychosocial, emphasizing importance integrated treatment approaches disrupt improve outcomes when possible.

Language: Английский

Citations

1