Assessment of Knowledge, Attitude, and Associated Factors of Mpox Among Healthcare Professionals at Debre Tabor Comprehensive Specialized Hospital, Northwest Ethiopia, 2024: A Cross‐Sectional Study
Teklehaimanot Kiros,
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Mulat Erkihun,
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Mitikie Wondmagegn
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et al.
Health Science Reports,
Journal Year:
2025,
Volume and Issue:
8(1)
Published: Jan. 1, 2025
ABSTRACT
Background
Mpox
is
a
zoonotic
disease
that
has
become
significant
public
health
concern,
especially
in
regions
beyond
its
usual
endemic
areas
Africa.
The
rising
global
incidence
and
classification
as
Public
Health
Emergency
of
International
Concern
by
the
World
Organization
highlight
importance
healthcare
professionals
(HCPs)
being
knowledgeable
well‐prepared
to
effectively
manage
virus.
This
study
aims
assess
knowledge,
attitudes,
factors
associated
with
HCPs
regarding
infections
at
Debre
Tabor
Comprehensive
Specialized
Hospital
Northwest
Ethiopia.
Methods
Between
June
13th
September
3rd,
2024,
cross‐sectional
was
conducted,
among
384
selected
through
convenience
sampling.
A
pretested,
well‐structured,
questionnaire
used
sociodemographic
characteristics,
attitudes
HCPs.
collected
data
were
analyzed
using
descriptive
statistics
logistic
regression.
p
‐value
≤
0.05
considered
statistically
association.
Results
Out
participants,
majority
male
(55.47%)
aged
31–39
years
(33.85%).
Nurses
made
up
largest
professional
group
31.25%.
Only
28.13%
37.76%
demonstrated
good
knowledge
favorable
toward
Mpox,
respectively.
Interestingly,
prior
information
sources
about
likely
possess
(AOR
=
1.45,
0.002).
Conclusions
findings
emphasize
important
gaps
attitude
It
imperative
implement
targeted
educational
initiatives
such
dissemination,
training,
continuous
development
improve
capacity
respond
other
emerging
infectious
diseases.
Language: Английский
Plant-derived molecules in monkeypox management: insight and alternative therapeutic strategies
Beni-Suef University Journal of Basic and Applied Sciences,
Journal Year:
2025,
Volume and Issue:
14(1)
Published: Feb. 19, 2025
Abstract
The
WHO
and
CDC
recently
declared
monkeypox
virus
(MPXV)
a
zoonotic
disease
known
as
(Mpox)
Public
Health
Emergency
of
International
Concern.
According
to
the
CDC,
no
treatment
is
specifically
approved
for
Mpox
infections.
Medicinal
plants
are
crucial
in
healthcare
economic
development,
particularly
low-
middle-income
countries.
This
review
offers
valuable
insights
into
pathogenesis
management
through
therapeutic
approaches
vaccination
strategies
using
plant-based
molecules.
Core
structural
proteins
necessary
both
viral
entry
immune
response,
including
A29,
H3L,
L1R,
involved
MPXV.
Potential
targets
vaccines
include
like
A35R
B6R,
which
essential
propagation
viruses.
MPXV
evades
system
by
concealing
its
DNA,
suppressing
interferon
limiting
T
NK
cell
activation,
preventing
apoptosis,
complicating
vaccine
development.
Antivirals
(tecovirimat,
brincidofovir)
vaccinations
(JYNNEOS,
ACAM2000)
manage
Mpox.
A
recent
study
revealed
early
clinical
trial
results,
indicating
that
antiviral
drug
tecovirimat,
well-known
conventional
treatment,
more
effective
than
placebo
against
clade
I
type
Research
gaps,
low
effectiveness,
availability
challenges.
novel
perspective
on
combating
global
threat
investigating
alternative
centered
plant-derived
compounds.
Graphical
Language: Английский
Assessment of healthcare workers knowledge and attitudes towards Mpox infection at University of Gondar Comprehensive Specialized Referral Hospital, Ethiopia
Frontiers in Public Health,
Journal Year:
2025,
Volume and Issue:
13
Published: March 3, 2025
Background
Healthcare
workers
are
on
the
frontlines
of
fighting
health
risks,
especially
during
epidemics.
Despite
their
critical
role,
knowledge
and
attitudes
toward
Mpox
have
not
been
previously
evaluated
at
University
Gondar
Comprehensive
Specialized
Hospital,
Ethiopia.
This
study
aimed
to
assess
healthcare
regarding
this
hospital.
Method
cross-sectional
assessing
382
HCWs.
It
was
conducted
August
1–30,
2024.
Data
collected
using
a
self-administered
questionnaire.
A
simple
random
sampling
technique
used.
Bivariate
multivariate
binary
logistic
regression
analysis
p
<
0.05
considered
as
Significant.
Result
Almost
half
participants
(48.40%)
showed
good
knowledge,
49.20%
displayed
positive
attitude
Mpox.
Age
≥
50
Years
old
(AOR
=
4.1,
95%
CI
1.33–12.07),
Physicians
3.2,
1.57–6.50),
pharmacists
3.5,
1.55–8.06),
having
B.Sc.
Degree
1.58–6.84),
M.Sc.
3.3,
1.60–6.84),
work
experience
5–10
years
1.78–5.95),
HCWs
who
get
information
primarily
from
training
2.7,
1.08–6.70),
attending
including
1.9,
1.16–3.19)
were
more
likely
than
counter.
those
degree
2.1,
1.11–4.20),
physician
1.10–4.16),
pharmacist
2.6,
1.21–5.76),
2.5,
1.44–4.38),
1.18–3.07)
Conclusion
revealed
nearly
had
limited
negative
attitudes.
To
addressing
gap
it
is
essential
support
training,
integrate
education,
improve
resource
accessibility.
Language: Английский
Effectiveness of Public Health Campaigns on Mpox Awareness and Prevention in Rural India
Muniba Afzal,
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Ashok Kumar Sah
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Infectious Diseases in Clinical Practice,
Journal Year:
2025,
Volume and Issue:
33(3)
Published: March 28, 2025
Abstract
This
review
examines
the
current
state
of
Mpox
awareness
and
prevention
strategies
in
India,
with
a
particular
focus
on
rural
underserved
communities.
As
Mpox,
virus
endemic
to
West
Central
Africa,
begins
spread
globally,
including
effective
public
health
responses
become
increasingly
critical.
The
evaluates
various
campaigns,
government-led
programs,
NGO
initiatives,
digital
traditional
media
efforts,
community-based
outreach.
It
highlights
role
educational
initiatives
such
as
school
training
for
local
workers,
use
mobile
units
improving
preventive
measures.
Challenges
socioeconomic
barriers,
limited
healthcare
infrastructure,
misinformation,
language
literacy
issues
are
discussed.
also
assesses
effectiveness
through
success
stories,
identified
gaps,
community
feedback.
Recommendations
provided
enhancing
prevention,
emphasizing
need
stronger
partnerships,
technological
integration,
culturally
tailored
communication,
increased
capacity
building
workers.
Future
research
directions
suggested,
focusing
bridging
gaps
awareness,
developing
sustainable
policy
strategies,
integrating
broader
initiatives.
underscores
importance
comprehensive
approach
addressing
combining
government
engagement,
innovative
achieve
lasting
impact.
Language: Английский
The willingness of healthcare workers to be vaccinated against monkeypox and their knowledge about monkeypox: A systematic review and meta-analysis
Heliyon,
Journal Year:
2024,
Volume and Issue:
10(15), P. e35196 - e35196
Published: July 30, 2024
Vaccination
is
an
important
method
to
address
the
monkeypox
epidemic.
We
aimed
analyze
knowledge
of
healthcare
workers
(HCWs)
about
human
and
their
attitudes
toward
vaccination.MethodsWe
searched
PubMed,
Embase
Web
Science
for
articles
performed
a
meta-analysis
using
Stata
14.0
with
random-effects
model.
This
study
was
conducted
in
accordance
Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
(PRISMA)
statement.
Language: Английский
Assessment of knowledge and attitude of healthcare professionals towards Mpox in a Nigerian hospital
Edidiong Orok,
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God’sTreasure Adele,
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Olawale Oni
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et al.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: Nov. 11, 2024
Mpox
is
a
zoonotic
viral
disease
that
presents
significant
public
health
challenges.
Despite
the
pivotal
role
of
healthcare
workers,
research
on
their
knowledge
and
attitudes
towards
mpox
limited.
This
study
aimed
to
assess
workers'
knowledge,
awareness
attitude
regarding
as
well
associated
factors
at
Rivers
State
University
Teaching
Hospital
in
Nigeria.
A
descriptive
cross-sectional
design
was
employed,
utilizing
34-item
semi-structured
questionnaire.
Knowledge
levels
were
categorized
good
(>
70%
score),
fair
(50-69%),
or
poor
(<
50%),
while
classified
positive
moderate
negative
50%).
Statistical
analyses
included
independent
sample
T-test,
One-way
Analysis
Variance,
Chi-square
tests.
Among
total
227
professionals,
majority
females
(59%)
singles
(54.2%).
Over
79%
correctly
identified
infection,
59.9%
recognized
its
potential
transmission
through
monkey
bite.
Overall,
22.5%
demonstrated
knowledge.
Majority
(61.7%)
acknowledged
worldwide
pandemic,
with
89%
agreeing
it
could
strain
affected
countries'
systems.
Healthcare
workers
exhibited
mpox.
Gender
(Males,
(p
=
0.003),
age
40
years
0.008),
experience
(6-10
years;
<
0.001),
professional
qualification
(physicians,
0.002),
previous
training
0.001)
significantly
influenced
levels,
but
no
associations
found
between
demographic
variables
attitudes.
The
revealed
high
level
low
among
most
participants.
professionals
also
Factors
such
gender,
age,
experience,
qualification,
did
not
influence
participants
highlighting
importance
targeted
educational
interventions.
Language: Английский
Assessment of knowledge and attitudes of the general population towards the monkeypox epidemic in Cameroon
Aimé Mbonda,
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Cyrille EWANE,
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Guy Sadeu Wafeu
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et al.
Research Square (Research Square),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 4, 2024
Abstract
Background
Monkeypox
has
spread
beyond
endemic
regions,
leading
the
WHO
to
declarea
public
health
emergency
of
international
concern
(PHEIC)
in
July
2022
following
a
rapid
increase
cases.
This
study
aimed
describe
people's
knowledge
and
attitudes
towards
this
disease.
Method
We
conducted
an
analytical
cross-sectional
February
2023,
including
consenting
adults
three
regions
Cameroon
using
multi-stage
random-
sampling
method.
Socio-demographic
data
assessment
disease
were
collected
entered
directly
into
pre-designed
collection
sheet.
Factors
associated
with
identified
logistic
regression
model
factors
significantly
bivariate
analysis.
Results
included
2,807
individuals,
female
predominance
(60%)
andthe
majority
participants
aged
30–40
years.
More
than
80%
unaware
details
disease,
andfewer
20%
knew
its
routes
transmission
symptoms.
Secondary
or
higher
education
increased
monkeypox,
ORs
2.92
6.17
respectively,
while
access
information,
especially
via
radio
meetings,
was
key
factor
improving
knowledge.
Conclusion
Knowledge
monkeypox
are
limited
general
population.
Education
information
channels
such
as
social
networks
arecrucial
for
preventing
disease.
Language: Английский
Knowledge of Mpox, Media Exposure, and Clinical Experience:
Aime Fidele Ndayiragije Mvuyekure,
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Daniel Muhayimana,
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Simon Pierre Ndayishimye MVuyekure
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et al.
Pan-African Journal of Health and Environmental Science,
Journal Year:
2024,
Volume and Issue:
3(2), P. 74 - 89
Published: Dec. 26, 2024
Background:
This
study
aimed
to
determine
the
predictors
of
nursing
students’
preparedness
for
disease
outbreaks
and
relationships
between
knowledge
Mpox,
media
exposure,
clinical
experience,
as
moderated
by
demographic
variables.
One
hundred
respondents
were
selected
using
stratified
random
sampling
from
four
academic
levels
at
University
Gitwe.
Methods:
The
employed
a
Quantitative
research
design.
results
indicated
that
had
high
Mpox
(66%),
exposure
(mean
=
2.69,
SD
0.743),
substantial
experience
2.58,
0.794).
Despite
facing
certain
challenges,
there
was
level
outbreaks,
particularly
concerning
2.77,
0.73).
Findings:
found
negligible
non-significant
correlation
with
(rho
-0.077,
p
0.445).
Conversely,
exhibited
moderate
positive
0.636,
<
0.001),
while
showed
but
relationship
(R²
0.142).
Conclusion:
findings
suggest
training
programs
enhance
manage
outbreaks.
Media
identified
most
significant
predictor
preparedness.
Based
on
these
findings,
it
is
recommended
integrate
literacy,
structured
training,
disaster
workshops
into
education
curricula
strengthen
capacity
respond
public
health
emergencies
effectively.
Language: Английский