Harmonious Allies: The Synergy of Antimicrobial Proteins and Microbes in Breast Milk to Protect Neonatal Health DOI Creative Commons
Alba Soledad Aquino-Domínguez,

Melisa Gómez-López,

Sergio Roberto Aguilar-Ruíz

et al.

Hygiene, Journal Year: 2025, Volume and Issue: 5(2), P. 19 - 19

Published: May 8, 2025

Breast milk is vital for infant survival, protecting against infections and strengthening the immune system. In addition to nutrients, breast contains beneficial microorganisms, antimicrobial peptides proteins (APPs), including lactoferrin lysozyme, such as defensins cathelicidins that destroy harmful bacteria regulate neonatal response. also promotes growth of gut (Bacteroidaceae Bifidobacteriaceae) while reducing pathogens, fostering a healthy microbiome, supporting long-term health. Traditionally, research on microbiota has been conducted in isolation. However, at molecular level, these components do not function independently; they interact synergistically, influencing immunomodulation, inflammation, composition microbiome. Therefore, this review aims provide an overview discovery identification APPs milk, dynamic relationship between microbiota, potentiation artificial feeding with supplemented formulas when breastfeeding impossible, benefits newborn systems, even tissue.

Language: Английский

Exclusive Human Milk Diet Is Associated with Lower Risk of Motor Function Impairment by Three Years of Age DOI Creative Commons
Fu‐Sheng Chou, Jing Zhang,

Maria Fe Villosis

et al.

Research Square (Research Square), Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

Abstract Objectives: To evaluate the association of an exclusive human milk diet (EHMD) with motor function by three years corrected age among infants born at less than 32 weeks gestation. Methods: We conducted a retrospective study between 2018 and 2021. Infants who received EHMD for > 75% days first day fortification 33 6/7 postmenstrual were assigned to group. used inverse propensity sores balance potential confounders developed mixed-effects logistic regression model assess association. Results: After adjusting demographics morbidities, was found be associated reduced risk impairment, odds ratio 0.74 (95% confidence interval 0.56–0.98, p-value = 0.033). Conclusions: An is decrease in early childhood impairment

Language: Английский

Citations

0
The shifting landscape of the preterm brain DOI
Panagiotis Kratimenos, Georgios Sanidas, Gabriele Simonti

et al.

Neuron, Journal Year: 2025, Volume and Issue: unknown

Published: April 1, 2025

Language: Английский

Citations

0
Transforming neonatal nursing: a randomized controlled trial comparing kangaroo care and standard protocols for survival in preterm infants with respiratory distress syndrome DOI Creative Commons
Osama Mohamed Elsayed Ramadan, Afrah Madyan Alshammari, Abeer Nuwayfi Alruwaili

et al.

BMC Nursing, Journal Year: 2025, Volume and Issue: 24(1)

Published: April 16, 2025

Language: Английский

Citations

0
Exclusive human milk diet is associated with lower risk of motor function impairment at three years of corrected age DOI Creative Commons
Fu‐Sheng Chou, Jing Zhang,

Maria Fe Villosis

et al.

Journal of Perinatology, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

To evaluate the association between an exclusive human milk diet (EHMD) and motor function impairment at three years of corrected age among infants born before 32 weeks gestation. We conducted a retrospective study 2018 2021. assigned to EHMD group who received for ≥75% days first day fortification 33 6/7 postmenstrual age. used inverse propensity scores balance potential confounders developed mixed-effects logistic regression model assess association. After adjusting demographics morbidities, was associated with reduced risk impairment, odds ratio 0.74 (95% CI: 0.56-0.98, p = 0.036). An is decrease in early childhood

Language: Английский

Citations

0
Harmonious Allies: The Synergy of Antimicrobial Proteins and Microbes in Breast Milk to Protect Neonatal Health DOI Creative Commons
Alba Soledad Aquino-Domínguez,

Melisa Gómez-López,

Sergio Roberto Aguilar-Ruíz

et al.

Hygiene, Journal Year: 2025, Volume and Issue: 5(2), P. 19 - 19

Published: May 8, 2025

Breast milk is vital for infant survival, protecting against infections and strengthening the immune system. In addition to nutrients, breast contains beneficial microorganisms, antimicrobial peptides proteins (APPs), including lactoferrin lysozyme, such as defensins cathelicidins that destroy harmful bacteria regulate neonatal response. also promotes growth of gut (Bacteroidaceae Bifidobacteriaceae) while reducing pathogens, fostering a healthy microbiome, supporting long-term health. Traditionally, research on microbiota has been conducted in isolation. However, at molecular level, these components do not function independently; they interact synergistically, influencing immunomodulation, inflammation, composition microbiome. Therefore, this review aims provide an overview discovery identification APPs milk, dynamic relationship between microbiota, potentiation artificial feeding with supplemented formulas when breastfeeding impossible, benefits newborn systems, even tissue.

Language: Английский

Citations

0