Monitoring of mental health in occupational populations: a study on the role and application of HDL-related inflammatory index DOI Creative Commons

Ma Jingxuan,

Pingcuo Yuzhen,

Li Zhen

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 31, 2025

Mental disorders in occupational populations pose significant health and economic burdens, but there exists a lack of practical objective biomarkers for mental monitoring. Our study aims to explore the correlation between high-density lipoprotein (HDL)-related inflammatory markers negative psychological symptoms populations. We also seek evaluate potential application effectiveness these indicators as identifying impact on Moreover, found this can be used high-risk groups prone responses caused by symptoms. adopted cross-sectional design with combination questionnaires biochemical index tests 1920 eligible The Depression Anxiety Stress Scales-21 (DASS-21) was measure participants' levels anxiety, depression, stress. Collect individual characteristics survey respondents through self-administered questionnaires. Blood samples are collected cholesterol peripheral blood cell counts. employed statistical analyses including analysis, Receiver Operating Characteristic (ROC) curve univariate multivariate regression. final sample size included analysis 1,434. results showed that stress, depressive were significantly correlated all four HDL-related indices (p < 0.05). Especially MHR, compared those without symptoms, individuals experiencing or depression had an OR 2.75 (95% CI: 1.90, 3.99), 3.27 2.25, 4.78), 3.02 2.08, 4.40) abnormally high levels, respectively. In addition, subgroup lower monthly incomes, longer working hours frequent night shifts might promoting factors elevated levels. further demonstrated PHR MHR exhibit good predictive ability three AUC values exceeding 0.6. Notably, over 30 years work experience, performance is even higher, reaching above 0.7. suggest expected problems groups, providing valuable information assessment. Preventive measures should implemented low income, long hours, shifts, mitigate impacts.

Language: Английский

Monitoring of mental health in occupational populations: a study on the role and application of HDL-related inflammatory index DOI Creative Commons

Ma Jingxuan,

Pingcuo Yuzhen,

Li Zhen

et al.

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 31, 2025

Mental disorders in occupational populations pose significant health and economic burdens, but there exists a lack of practical objective biomarkers for mental monitoring. Our study aims to explore the correlation between high-density lipoprotein (HDL)-related inflammatory markers negative psychological symptoms populations. We also seek evaluate potential application effectiveness these indicators as identifying impact on Moreover, found this can be used high-risk groups prone responses caused by symptoms. adopted cross-sectional design with combination questionnaires biochemical index tests 1920 eligible The Depression Anxiety Stress Scales-21 (DASS-21) was measure participants' levels anxiety, depression, stress. Collect individual characteristics survey respondents through self-administered questionnaires. Blood samples are collected cholesterol peripheral blood cell counts. employed statistical analyses including analysis, Receiver Operating Characteristic (ROC) curve univariate multivariate regression. final sample size included analysis 1,434. results showed that stress, depressive were significantly correlated all four HDL-related indices (p < 0.05). Especially MHR, compared those without symptoms, individuals experiencing or depression had an OR 2.75 (95% CI: 1.90, 3.99), 3.27 2.25, 4.78), 3.02 2.08, 4.40) abnormally high levels, respectively. In addition, subgroup lower monthly incomes, longer working hours frequent night shifts might promoting factors elevated levels. further demonstrated PHR MHR exhibit good predictive ability three AUC values exceeding 0.6. Notably, over 30 years work experience, performance is even higher, reaching above 0.7. suggest expected problems groups, providing valuable information assessment. Preventive measures should implemented low income, long hours, shifts, mitigate impacts.

Language: Английский

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