The value of environmental surveillance for pandemic response DOI Creative Commons
Pedro Nascimento de Lima,

Stephen L. Karr,

Jing Zhi Lim

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 22, 2024

Environmental sampling surveillance (ESS) technologies, such as wastewater genomic and air sensors, have been increasingly adopted during the COVID-19 pandemic to provide valuable information for public health response. However, ESS coverage is not universal, decision-makers need support choose whether how expand sustain efforts. This paper introduces a model approach quantify value of systems that leading epidemiological indicators Using base-case scenario, we in first year new demonstrate depends on biological societal parameters. Under baseline assumptions, an system provides 5-day early warning relative syndromic could reduce deaths from 149 (95% prediction interval: 136–169) 134 (124–144) per 100,000 population COVID-19-like pandemic, resulting net monetary benefit $1,450 ($609-$2,740) person. The system's higher more transmissible deadly pathogens but hinges effectiveness interventions. Our findings also suggest would net-positive benefits even if they were permanently maintained like SARS-Cov-2 emerged once every century or less frequently. results can be used prioritize ESS, decide currently uncovered populations, determine scale systems' over time.

Language: Английский

A Binary Prototype for Time-Series Surveillance and Intervention DOI Creative Commons
Jason Olejarz, Till Hoffmann, Antonia Zapf

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 5, 2025

Abstract Despite much research on early detection of anomalies from surveillance data, a systematic framework for appropriately acting these signals is lacking. We addressed this gap by formulating hidden Markov-style model time-series surveillance, where the system state, observed and decision rule are all binary. incur delayed cost, c , whenever abnormal no action taken, or an immediate k with action, < . If costs too high, then detrimental, intervention should never occur. sufficiently low, always Only when intermediate low beneficial. Our equations provide assessing which approach may apply under range scenarios and, if warranted, facilitate methodical classification strategies. thus offers conceptual basis designing real-world public health systems.

Language: Английский

Citations

0
Diagnostics for Public Health — Infectious Disease Surveillance and Control DOI
Marc Lipsitch, Yonatan H. Grad

NEJM Evidence, Journal Year: 2024, Volume and Issue: 3(5)

Published: April 23, 2024

Accurate diagnostics are critical in public health to ensure successful disease tracking, prevention, and control. Many of the same characteristics desirable for diagnostic procedures both medicine health: example, low cost, high speed, invasiveness, ease use interpretation, day-to-day consistency, accuracy. This review lays out five principles that salient when goal diagnosis is improve overall a population rather than particular patient, it applies them two important cases: pandemic infectious antimicrobial resistance.

Language: Английский

Citations

2
The value of environmental surveillance for pandemic response DOI Creative Commons
Pedro Nascimento de Lima,

Stephen L. Karr,

Jing Zhi Lim

et al.

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: Nov. 22, 2024

Environmental sampling surveillance (ESS) technologies, such as wastewater genomic and air sensors, have been increasingly adopted during the COVID-19 pandemic to provide valuable information for public health response. However, ESS coverage is not universal, decision-makers need support choose whether how expand sustain efforts. This paper introduces a model approach quantify value of systems that leading epidemiological indicators Using base-case scenario, we in first year new demonstrate depends on biological societal parameters. Under baseline assumptions, an system provides 5-day early warning relative syndromic could reduce deaths from 149 (95% prediction interval: 136–169) 134 (124–144) per 100,000 population COVID-19-like pandemic, resulting net monetary benefit $1,450 ($609-$2,740) person. The system's higher more transmissible deadly pathogens but hinges effectiveness interventions. Our findings also suggest would net-positive benefits even if they were permanently maintained like SARS-Cov-2 emerged once every century or less frequently. results can be used prioritize ESS, decide currently uncovered populations, determine scale systems' over time.

Language: Английский

Citations

0