Microbiome Research Reports, Journal Year: 2024, Volume and Issue: 4(1)
Published: Dec. 23, 2024
Breast milk plays a crucial role in shaping the gut microbiota of preterm infants, with significant microbial sharing influenced by feeding practices and antibiotics, highlighting benefits direct breastfeeding for health.
Language: Английский
Pediatric Allergy and Immunology, Journal Year: 2025, Volume and Issue: 36(1)
Published: Jan. 1, 2025
We read with great interest the article, "Duration of Food Protein-Induced Allergic Proctocolitis (FPIAP) and Role Intestinal Microbiota," which provides valuable insights into natural history microbiota-related aspects FPIAP.1 The findings that FPIAP duration may be shorter than traditionally perceived symptomatic infants exhibit microbiota profiles dominated by Klebsiella Shigella significantly enhance our understanding this condition. Nonetheless, we believe several warrant further exploration clarification. First, while commend authors for their insightful in infants, would like to emphasize a potential limitation specifically related breastfed was not explicitly addressed study. Maternal health conditions, such as mastitis, or use medications antibiotics during lactation, could have significant impact on composition infant's gut and, consequently, progression FPIAP.2, 3 Antibiotics, instance, are known disrupt maternal milk microbiota, potentially introducing changes alter microbial environment.3 This confound observed relationship between dietary factors clinical outcomes. Furthermore, early signs mild swelling tenderness, sometimes mistaken typical postpartum lactation changes, leading underreporting undiagnosed cases.4 Subclinical mastitis influence immunological breast milk, thereby variability outcomes infants.4 By accounting factors, study might overlooked critical contributors shifts resolution. recommend future research incorporate detailed assessments lactation-related better understand dynamics trajectory infants. Additionally, discussion intestinal microbiota's role remission is compelling, it somewhat cursory. identification enterotypes transitioning Bacteroides Bifidobacterium clusters maturation, insightful. However, mechanisms underlying these connection pathogenesis remain unexplored. Given mucosal immunity through short-chain fatty acid (SCFA) production regulatory T cell (Treg) modulation,5 studies incorporating longitudinal metabolomic transcriptomic analyses offer how metabolites immune pathways interact resolve promote tolerance. In conclusion, its association addressing delving deeper maturation Incorporating only strengthen study's but also contribute more comprehensive FPIAP's Quanjie Hu: Conceptualization; writing – review editing; original draft. Zhuoxuan Lv: Hongxia Niu: supervision; draft; editing. declare no conflict interest. peer article available at https://www.webofscience.com/api/gateway/wos/peer-review/10.1111/pai.70023. Data sharing applicable new data were created analyzed
Language: Английский
Citations
1
Nutrients, Journal Year: 2024, Volume and Issue: 16(23), P. 4122 - 4122
Published: Nov. 28, 2024
Human milk contains an abundance of nutrients which benefit the development and growth infants. However, infant formula has to be used when breastfeeding is not possible. The large differences between human in prebiotics lead suboptimal intestinal health formula-fed This functional deficit may overcome through other dietary polysaccharides that have been characterized. aim this review was summarize potential applications as prebiotics, synbiotics, postbiotics better mimic functionality for gut health. Previous studies demonstrated influences on microbiota, SCFA production, immune system development. Compared synbiotics showed application shaping prevention pathogen infections, system. Moreover, safety issues biotics still require more clinical trials with a large-scale population long time duration, generally accepted regulations are important regulate related products. Pectin similar impacts oligosaccharides microbiota repairing damaged barrier, functions also being observed inulin β-glucan. Prebiotics encapsulation material combined probiotics compared traditional formula.
Language: Английский
Citations
5
World Journal of Clinical Pediatrics, Journal Year: 2025, Volume and Issue: 14(2)
Published: March 18, 2025
Breast milk represents the gold standard for neonatal nutrition, especially preterm and term infants with a low birthweight. This awareness is based not only on nutritional properties of human milk, which specifically designed growth humans but also breast milk’s non-nutritional properties, such as protection against infection. In fact, should be considered heterogeneous ecosystem, including wide range cells in addition to those involved immune function; factors, vascular endothelial factor; multiple noncoding microRNAs; cells; epithelial multipotent mesenchymal stem cells. recent identification pool progenitor driving force behind growing research aimed at identifying nature these stem/progenitor their sources.
Language: Английский
Citations
0
Gut Microbes, Journal Year: 2024, Volume and Issue: 16(1)
Published: Oct. 20, 2024
Background The human gut microbiome develops rapidly during infancy, a key window of development coinciding with the maturation adaptive immune system. However, little is known about growth dynamics over first few months life and whether there are any generalizable patterns across populations. We performed metagenomic sequencing on stool samples (n = 94) from cohort infants 15) at monthly intervals in 6 life, augmenting our dataset seven published studies for total 4,441 metagenomes 1,162 infants.
Language: Английский
Citations
2
Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15
Published: Sept. 27, 2024
Background In recent years, the prevalence of childhood obesity has escalated alarmingly, posing significant threats to physical and mental well-being children, with an elevated likelihood persisting into adulthood. Notably, investigations have uncovered a profound association between intestinal microbiota, crucial component internal milieu, obesity. Disturbances in microbiota their by-products are now understood be profoundly intertwined evolutionary pathway Bibliometric analysis offers deep understanding current research landscape, so we apply it review emerging trends patterns gut microbiota. Materials methods We conducted rigorous extensive search Web Science (WoS) Core Collection database, spanning years from 1900 2023, analyze scholarly articles pertaining Utilizing VOSviewer, CiteSpace, R package “bibliometrix,” online bibliometric platform ( https://bibliometric.com/ ), delved intricate details hotspots, academic collaborations, within this domain. Results The exhaustive encompassed globe, uncovering cumulative total 1,384 pertinent studies originating 429 nations. results were compelling, revealing influence exerted by United States China specific field research. Furthermore, was observed that volume works is steadily growing year on year. hot topics include “abuse,” “maltreatment,” “adverse experiences,” “students,” “food addiction”. Conclusion This comprehensive meticulous exploration evolving agendas over past two decades. It strives equip researchers thorough key nations, institutions, journals, potential collaborators these specialized fields. Additionally, sheds light frontiers strategic avenues for further exploration, thus serving as invaluable resource scholars delving deeper intricacies microbiome.
Language: Английский
Citations
1
Microorganisms, Journal Year: 2024, Volume and Issue: 12(8), P. 1582 - 1582
Published: Aug. 2, 2024
Probiotics are “live microorganisms which, when administered in adequate amount, confer health benefits on the host”. They can be found certain foods like yogurt and kefir dietary supplements. The introduction of bacterial derivatives has not only contributed to disease control but also exhibited promising outcomes, such as improved survival rates, immune enhancement, growth promotion effects. It is interesting note that efficacy probiotics goes beyond viability bacteria, giving rise concepts paraprobiotics, non-viable forms probiotics, postbiotics. Paraprobiotics offer various children with intestinal dysbiosis, contributing digestive health, function, overall well-being. In this review, potential these therapeutic applications alternatives pharmacological agents for treating pediatric dysbiosis will thoroughly evaluated. This includes an analysis their efficacy, safety, long-term benefits, ability restore gut microbiota balance, improve enhance reduce inflammation. aim determine if non-pharmacological interventions effectively safely manage children, reducing need conventional medications side
Language: Английский
Citations
0
Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12
Published: Nov. 6, 2024
The benefits of breastfeeding are widely established and therefore the World Health Organization recommends that every child be exclusively breastfed for first 6 months life continue up to 2 years age or beyond. However, rate exclusive is low globally has declined in Bangladesh recent years. In this review, used as an example demonstrate complex individual- system-level determinants a low-resource setting. Mothers face barriers within context marketing by commercial milk formula companies, limited safe alternatives directly from breast, insufficient resources support hospital, community, workplace Future research implementation science required investigate overlapping effects between high antibiotic use Caesarean section rates Bangladesh, along with public health efforts promote based on robust evidence.
Language: Английский
Citations
0
Microbiome Research Reports, Journal Year: 2024, Volume and Issue: 4(1)
Published: Dec. 23, 2024
Breast milk plays a crucial role in shaping the gut microbiota of preterm infants, with significant microbial sharing influenced by feeding practices and antibiotics, highlighting benefits direct breastfeeding for health.
Language: Английский
Citations
0