Association between magnesium depletion score and prostate cancer DOI Creative Commons

Hongyang Gong,

Xiaomei Lin,

Shaoqun Huang

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 8, 2025

The Magnesium Depletion Score (MDS) is a practical tool used to assess magnesium deficiency. Studies have indicated that MDS associated with various urological conditions, such as kidney stones and the prognosis of chronic disease. However, relationship between prostate cancer (PCa) remains unclear. Therefore, this study aims investigate association PCa. This conducted cross-sectional analysis 16,043 participants from 2005–2018 NHANES database. Subgroup analysis, restricted cubic splines (RCS), multivariable logistic regression were employed examine prevalence A total included in study, whom 511 had After adjusting for all variables using regression, each 1-unit increase was 26% higher PCa (OR = 1.26, 95% CI: 1.05, 1.50). Additionally, compared an 0, 3 or 3.04-fold 3.04, 1.53, 6.01). RCS demonstrated significant linear positive correlation prevalence. generally consistent across different population groups. indicates risk PCa, linked increased These findings highlight potential role Further research needed determine whether causal exists which would help appropriateness interventions.

Language: Английский

Association between magnesium depletion score and prostate cancer DOI Creative Commons

Hongyang Gong,

Xiaomei Lin,

Shaoqun Huang

et al.

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: Feb. 8, 2025

The Magnesium Depletion Score (MDS) is a practical tool used to assess magnesium deficiency. Studies have indicated that MDS associated with various urological conditions, such as kidney stones and the prognosis of chronic disease. However, relationship between prostate cancer (PCa) remains unclear. Therefore, this study aims investigate association PCa. This conducted cross-sectional analysis 16,043 participants from 2005–2018 NHANES database. Subgroup analysis, restricted cubic splines (RCS), multivariable logistic regression were employed examine prevalence A total included in study, whom 511 had After adjusting for all variables using regression, each 1-unit increase was 26% higher PCa (OR = 1.26, 95% CI: 1.05, 1.50). Additionally, compared an 0, 3 or 3.04-fold 3.04, 1.53, 6.01). RCS demonstrated significant linear positive correlation prevalence. generally consistent across different population groups. indicates risk PCa, linked increased These findings highlight potential role Further research needed determine whether causal exists which would help appropriateness interventions.

Language: Английский

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