The association of nutritional and inflammatory status with cardiovascular and all-cause mortality risk among US patients with metabolic syndrome

Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)

Published: March 20, 2025

To investigate the relationship between nutritional and inflammatory status all-cause cardiovascular mortality in U.S. population with cardiometabolic syndrome (CMS) to identify optimal nutrition-inflammation index for assessing long-term prognosis. Health data from 1999–2010 National Nutrition Examination Survey (NHANES) were used. Kaplan-Meier analysis explored associations indices CMS population. Significant selected ROC curve analysis, most effective was analyzed using COX regression models. Restricted cubic splines (RCS) nonlinear associations, a recursive algorithm determined inflection points. Subgroup sensitivity analyses assessed stability of model. The study included 5,969 participants (2,900 males, 3,069 females), 1,753 deaths 607 deaths. indicated that good nutrition low inflammation linked better outcomes. Advanced Lung Cancer Inflammation Index (ALI) index. showed negative association ALI both types. RCS revealed U-shaped an L-shaped mortality, point at 106.24. confirmed robustness risk is ideal indicator evaluating Maintaining appropriate level can help reduce patients.

Language: Английский

The joint effects of sleep duration and exercise habit on all-cause mortality among Chinese older adult: a national community-based cohort study

Frontiers in Public Health, Journal Year: 2025, Volume and Issue: 13

Published: March 26, 2025

Abstract This study examines the combined effects of sleep duration and exercise habits on all-cause mortality in older Chinese adults using data from Longitudinal Healthy Longevity Survey (CLHLS). Methods Data were collected 7231 residents aged 60 above CLHLS. Participants categorized based their (short sleep: <6 hours, normal 6–8 long >8 hours) (physically active, physically inactive, inactive-to-active, active-to-inactive). The analysis was conducted over three follow-up periods (2011, 2014, 2018). Cox proportional hazards regression models used to assess associations between duration, habits, mortality. Results results showed that compared short sleepers, individuals with (6–8 had a slightly reduced risk death, although this reduction not statistically significant (HR = 0.97, 95% CI 0.87–1.08). In contrast, sleepers (>8 significantly higher 1.28, 1.16–1.43). Regarding regular or transitioning inactivity those who did 0.74, 0.66–0.83 HR 0.88, 0.80–0.97, respectively). Notably, impact among regardless gender. However, both men women experienced benefits exercise. Additionally, transitioned sedentary lifestyle physical activity during demonstrated lower rates. Conclusion Both are associated adults, notable gender differences effects. Targeted health policies encourage improved while considering gender-specific needs, essential reduce enhance quality life population.

Language: Английский