The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts DOI Creative Commons
Hugo Pereira, Joseph I. Hoffman,

Oliver Krüger

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 10, 2024

The gut microbiota-immune-brain axis is a feedback network which influences diverse physiological processes and plays pivotal role in overall health wellbeing. Although research humans laboratory mice has shed light into the associations mechanisms governing this communication network, evidence of such interactions wild, especially young animals, lacking. We therefore investigated these during early development population common buzzards (

Language: Английский

The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts DOI Creative Commons
Hugo Pereira,

Joseph I. Hoffamn,

Oliver Krüger

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 1, 2024

ABSTRACT The gut microbiota-immune-brain axis is a feedback network which influences diverse physiological processes and plays pivotal role in overall health well-being. Although research humans laboratory mice has shed light into the associations mechanisms governing this communication network, evidence of such interactions wild, especially young animals, lacking. We therefore investigated these during early development population common buzzards ( Buteo buteo ) their effects on individual condition. In longitudinal study, we used multi-marker approach to establish potential links between bacterial eukaryotic microbiota, panel immune assays feather corticosterone measurements as proxy for long-term stress. Using Bayesian structural equation modelling, found no support microbial diversity or stress parameters. However, did find strong relationships network. Immunity was negatively correlated with levels, positively associated nestling body Furthermore, levels microbiota decreased age while activity increased. absence conclusive buzzard nestlings, coupled mediated immunosuppression, suggests dominating stress-dominated maturation system development. Confounding factors inherent wild systems developing animals might override known from adult model subjects. positive association condition indicates benefits possessing stable microbiota.

Language: Английский

Citations

0
The gut microbiota-immune-brain axis in a wild vertebrate: dynamic interactions and health impacts DOI Creative Commons
Hugo Pereira, Joseph I. Hoffman,

Oliver Krüger

et al.

Frontiers in Microbiology, Journal Year: 2024, Volume and Issue: 15

Published: Sept. 10, 2024

The gut microbiota-immune-brain axis is a feedback network which influences diverse physiological processes and plays pivotal role in overall health wellbeing. Although research humans laboratory mice has shed light into the associations mechanisms governing this communication network, evidence of such interactions wild, especially young animals, lacking. We therefore investigated these during early development population common buzzards (

Language: Английский

Citations

0