Vulvovaginal Candidiasis-An Overview of Current Trends and the Latest Treatment Strategies

Microbial Pathogenesis, Journal Year: 2025, Volume and Issue: unknown, P. 107359 - 107359

Published: Feb. 1, 2025

Language: Английский

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Candida albicans: the current status regarding vaginal infections

Applied Microbiology and Biotechnology, Journal Year: 2025, Volume and Issue: 109(1)

Published: April 10, 2025

Abstract Vaginal infections caused by Candida albicans are a significant global health concern due to their recurrence and negative impact on quality of life. This review examines the pathogenesis C. infections, emphasizing critical virulence factors such as biofilm formation, adherence, phenotypic switching. Risk include immune system suppression, antibiotic use, hormonal changes, all which can lead fungal overgrowth infection. Current prevention and/or treatment strategies primarily rely antifungal therapies, personal hygiene practices, probiotics. However, challenges like resistance, recurrence, limited efficacy highlight need for innovative approaches. Therefore, emerging methods novel agents, vaccines, nanotechnology-based delivery systems offer promising advancements improve infection control. Additionally, plays key role in preventing with both innate adaptive immunity acting restrict colonization growth. Commercially available products, creams, vaginal probiotics, solutions, practical options but often lack long-term efficacy. Persistent challenges, including patient noncompliance, restricted access hinder comprehensive efforts. Thus, future research should focus promoting interdisciplinary approaches, integrating personalized medicine, enhancing healthcare accessibility. intends present current state art within abovementioned issues enhance understanding multifactorial nature advanced strategies, essential reduce burden candidiasis worldwide life outcomes. Key points • involves biofilms, Vaccines, nanotechnology, new drugs improved treatment. Addressing resistance compliance is success. Graphical

Language: Английский

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Prevalence and Factors Associated With Sexually Transmitted Infections Among Women of Reproductive Age in Tanzania: A Cross‐Sectional Analysis of National Data

Health Science Reports, Journal Year: 2025, Volume and Issue: 8(5)

Published: April 29, 2025

Sexually Transmitted Infections (STIs) remain a significant public health concern, particularly among women of reproductive age (WRA) who face heightened vulnerability. Despite remarkable advancements in medicine, 1 million new cases STIs are recorded daily. In Tanzania, however, data on remains limited. This study seeks to bridge that gap by determining prevalence and factors associated with WRA Tanzania. was analytical cross-sectional using from the current Demographic Health Surveys (DHS) 2022. 15,254 weighed sample analyzed STATA version 18. Analysis considered complex survey design through application weights, clustering strata. Modified Poisson regression models estimated Results were presented adjusted relative risk (ARR) 95% confidence interval. The Tanzania 4.7%. After adjusting for other variables, following remained significantly WRA: aged 25-34 (ARR = 1.55, CI:1.22-1.95), rich household 1.39, CI: 1.02-1.89), marriage 0.81, CI:0.65-0.99) multiple sexual partners 1.80, CI:1.24-2.63). Although have relatively low (4.7%) Tanzanian WRA, behavioral change campaigns, young adult-friendly services, routine screening tailored preventive education crucial achieving universal goals, reducing infections, fostering overall well-being this vulnerable group.

Language: Английский

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Novel Vaginal Microbial Treatments

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

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