Bone Remodeling Around Implants with Different Macro-Design Placed in Post-Extraction Sockets: A Cone-Beam Computed Tomography (CBCT) Randomized Controlled Clinical Trial (RCT)

Dentistry Journal, Journal Year: 2025, Volume and Issue: 13(2), P. 78 - 78

Published: Feb. 11, 2025

Background: Immediate post-extraction dental implants are increasingly popular, but ensuring primary stability and managing peri-implant tissues remain challenging. Implant macro-design significantly impacts osseointegration. This study used Cone-beam Computed Tomography (CBCT) to evaluate changes in alveolar bone following immediate placement of two implant designs, System 2P Dura-Vit 3P, which feature semi-conical microgeometry apical self-tapping portions for improved regeneration. Methods: With a 1:1 allocation ratio, the current investigation was two-arm parallel group randomized clinical trial. Patients qualified if they required replacements with adequate buccal support. Two types were placed: (cylindrical shape) 3P (more conical shape, particular architecture threads). Following intervention, CBCT performed both immediately (T1) six months later (T2). Measurements horizontal level at apical, medial, bevel height on palatal/lingual vestibular sides as well vertical gap results. Complications, quotient (ISQ), torque insertion evaluated. The Mann–Whitney test determine time-based differences within each group, while Wilcoxon estimate between groups. impact baseline marginal dimension gingival biotype estimated using multiple regressions. Results: Thirty patients recruited treatments, lost follow-up. One failed dropped out. At T1, exhibited lower mean higher ISQ than group. Furthermore, showed reduction compared measurements significant palatal base medial (p-values < 0.05). Regression models indicated positive effect thick biotypes filling dimensional reduction. No complications observed Conclusions: exhibits high when inserted sites. this kind stimulates side implant. present findings support evidence that promotes increased reduces loss.

Language: Английский

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Dysbiosis of Oral Microbiome: A Key Player in Oral Carcinogenesis? A Critical Review

Biomedicines, Journal Year: 2025, Volume and Issue: 13(2), P. 448 - 448

Published: Feb. 12, 2025

The oral cavity is known to harbor hundreds of microorganisms, belonging various genera, constituting a peculiar flora called the microbiome. change in relative distribution constituents this microbial flora, due any reason, leads dysbiosis. For centuries, dysbiosis has been linked etiopathogenesis several medical illnesses, both locally and systemically-. However, aided by recent advent bio-technological capabilities, reports have re-emerged that link carcinogenesis, numerous studies are currently exploring their association plausible mechanisms. Some proposed mechanisms dysbiosis-induced carcinogenesis (ODIC) include—a bacteria-induced chronic inflammatory state leading direct cellular damage, inflammatory-cytokine-mediated promotion proliferation invasion, release bacterial products carcinogenic, suppression local immunity alteration tumor microenvironment. actual interactions between these role not yet fully understood. This review provides comprehensive overview hypotheses implicated ODIC, along with corresponding molecular aberrations. Apart from discussing usual microbiome profile, also summarizes profiles ODIC. sheds light on potential clinical implications research prevention management cancer.

Language: Английский

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General practitioners in the UK and implications for the healthcare system

Gazzetta Medica Italiana Archivio per le Scienze Mediche, Journal Year: 2025, Volume and Issue: 184(1-2)

Published: March 1, 2025

Language: Английский

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Pedicle flap with basal allograft revascularization: an alternative way to treat Miller's class I and II gingival recessions with AlloDerm®

Gazzetta Medica Italiana Archivio per le Scienze Mediche, Journal Year: 2025, Volume and Issue: 184(1-2)

Published: March 1, 2025

Language: Английский

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