Projections of wastewater as an indicator of COVID-19 cases in corrections facilities: a modelling study DOI Creative Commons
Dan Han, Pamela Linares, Rochelle H. Holm

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 31, 2023

Abstract Background Although prison facilities are not fully isolated from the communities they located within, majority of population is confined and requires high levels health vigilance protection. This study sought to examine dynamic relationship between facility level wastewater viral RNA concentration probability at least one positive COVID-19 case within facility. Methods The period was January 11, 2021 through May 12, 2023. Wastewater samples were collected analyzed for SARS-CoV-2 (N1) pepper mild mottle virus (PMMoV) three times per week across 14 in Kentucky (USA). Confirmed clinical reports also provided. A hierarchical Bayesian spatial-temporal model with a latent lagged process developed. Findings We modeled facility-specific normalized by PMMoV ratio associated an 80% probability. differs among facilities. Across facilities, our demonstrates average capture rate 94·95% via N1/PMMoV threshold p ts ≥ 0·5. However, it noteworthy as set higher, such 0·9 or above, model’s reduces 60%. robust performance underscores effectiveness accurately detecting presence cases incarcerated people. Interpretation findings this provide correction public response based on frequent surveillance.

Language: Английский

Behind the bars: Wastewater-based surveillance of SARS-CoV-2, and its variants in prison wastewater DOI Creative Commons
Siti Aishah Rashid, Khayri Azizi Kamel, Raheel Nazakat

et al.

Heliyon, Journal Year: 2025, Volume and Issue: 11(6), P. e43063 - e43063

Published: March 1, 2025

Language: Английский

Citations

0
Wastewater Surveillance for SARS-CoV-2 at Long-Term Care Facilities: Mixed Methods Evaluation DOI Creative Commons
James W. Keck,

Jess Lindner,

Matthew Liversedge

et al.

JMIR Public Health and Surveillance, Journal Year: 2023, Volume and Issue: 9, P. e44657 - e44657

Published: July 18, 2023

Wastewater surveillance provided early indication of COVID-19 in US municipalities. Residents long-term care facilities (LTCFs) experienced disproportionate morbidity and mortality the pandemic. We implemented LTCF building-level wastewater for SARS-CoV-2 at 6 Kentucky to provide warning populations considered vulnerable.This study aims evaluate performance LTCFs Kentucky.We conducted a mixed methods evaluation following Centers Disease Control Prevention (CDC) guidelines evaluating public health systems. Evaluation steps CDC were engaging stakeholders, describing system, focusing design, gathering credible evidence, generating conclusions recommendations. purposively recruited stakeholders semistructured interviews undertook thematic content analysis interview data. integrated wastewater, clinical testing, process data characterize or calculate 7 system attributes (simplicity, flexibility, quality, sensitivity positive predictive value [PPV], timeliness, representativeness, stability).We 8 stakeholder interviews. The collected samples (N=811) 2 4 times weekly from March 2021 February 2022. Synthesis evidence indicated variable performance. Regarding simplicity, implementation required moderate human resource technical capacity. efficiently adjusted frequency demonstrated ability detect additional pathogens interest. software identified errors sample metadata entry (110/3120, 3.53% fields), technicians polymerase chain reaction issues (140/7734, 1.81% reactions), staff entered all corrections into log. PPV, using routine testing results as gold standard, signal >0 RNA copies/mL was 30.6% (95% CI 24.4%-36.8%) sensitive 79.7% 76.4%-82.9%) specific test LTCF. PPV 34.8% 27.9%-41.7%) increased 75% 60%-90%) >250 copies/mL. received 24 72 hours after collection, with delayed reporting because lack weekend laboratory staff. challenges delineating population contributing visitors, unknown toileting habits, use adult briefs by some residents preventing their waste entering sewer system. stability, reoccurring cost conduct 1 day facility approximately $144.50, which included transportation, labor, materials expenses.The per criteria. Stakeholders found feasible expressed optimism regarding its potential while also recognizing interpreting acting on

Language: Английский

Citations

7
Wastewater Surveillance of SARS-CoV-2 RNA in a Prison Facility DOI Open Access
Ocean Thakali,

Shalina Shahin,

Samendra P. Sherchan

et al.

Water, Journal Year: 2024, Volume and Issue: 16(4), P. 570 - 570

Published: Feb. 15, 2024

Prison populations are unlikely to have access prompt, effective medical care as the general population. Therefore, vaccination and surveillance systems been recommended mitigate coronavirus disease 2019 (COVID-19) transmission in prison settings. This pilot study aimed assess application of wastewater-based epidemiology (WBE) a act an early warning tool for COVID-19 transmission. In this study, weekly wastewater samples (n = 21) were collected 21 weeks from facility New Orleans, LA, USA, analyzed severe acute respiratory syndrome 2 (SARS-CoV-2), results compared with number confirmed cases during same period. SARS-CoV-2 was concentrated using two methods quantified via RT-qPCR CDC N1 N2 assays. Overall, detected eight (38%). An equal tested positive concentrating methods, indicating effectiveness both building-scale WBE. Despite limited clinical testing studied facility, instances detection prior diagnosis depict potential use detecting presence averting outbreaks asymptomatic patients.

Language: Английский

Citations

2
Wastewater threshold as an indicator of COVID-19 cases in correctional facilities for public health response: a modeling study DOI
Dan Han, Pamela Linares, Rochelle H. Holm

et al.

Water Research, Journal Year: 2024, Volume and Issue: 260, P. 121934 - 121934

Published: June 12, 2024

Language: Английский

Citations

1
Title: Qualitative Assessment of a Novel Results-Based Partnership between National Wastewater Surveillance Centers of Excellence and Utility Companies, Houston (Texas), Colorado, Wisconsin, and California, 2023. DOI Creative Commons
Hannah Turner, Libby Horter, Michael Welton

et al.

Research Square (Research Square), Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 21, 2024

Abstract Background The U.S. Centers for Disease Control and Prevention (CDC) initiated the National Wastewater Surveillance System (NWSS) in September 2020. Four of Excellence (COEs) were established between 2021–2023 Houston (Texas), Colorado, Wisconsin, California to guide wastewater surveillance efforts public health. Our objective was increase understanding factors that facilitated implementation from perspectives experiences shared by health department COEs utility partners. Methods We used a purposive sampling strategy select eight key respondents four NWSS respective conducted in-depth interviews related identified common points interview transcription files. Insights on WWS partners distilled responses into lessons learned. Results Three primary themes emerged after we analyzed responses: perceived community benefits surveillance, collaboration trust building among helped program advancement, sustainability strategies considerations. Conclusion This analysis has highlighted importance partnerships collaborations.

Language: Английский

Citations

1
Evaluation of wastewater surveillance for SARS-CoV-2 in a prison population: a mixed-methods approach DOI Creative Commons

Gethin Jones,

Andrew Nelson, David R. Chadwick

et al.

Frontiers in Public Health, Journal Year: 2024, Volume and Issue: 12

Published: Nov. 19, 2024

Prisons are high-risk settings for the transmission of communicable disease. Robust surveillance systems required to identify and control outbreaks. Wastewater SARS-CoV-2 was introduced in four prisons Wales March 2022. We investigated its contribution COVID-19 programme.

Language: Английский

Citations

0
Projections of wastewater as an indicator of COVID-19 cases in corrections facilities: a modelling study DOI Creative Commons
Dan Han, Pamela Linares, Rochelle H. Holm

et al.

medRxiv (Cold Spring Harbor Laboratory), Journal Year: 2023, Volume and Issue: unknown

Published: Oct. 31, 2023

Abstract Background Although prison facilities are not fully isolated from the communities they located within, majority of population is confined and requires high levels health vigilance protection. This study sought to examine dynamic relationship between facility level wastewater viral RNA concentration probability at least one positive COVID-19 case within facility. Methods The period was January 11, 2021 through May 12, 2023. Wastewater samples were collected analyzed for SARS-CoV-2 (N1) pepper mild mottle virus (PMMoV) three times per week across 14 in Kentucky (USA). Confirmed clinical reports also provided. A hierarchical Bayesian spatial-temporal model with a latent lagged process developed. Findings We modeled facility-specific normalized by PMMoV ratio associated an 80% probability. differs among facilities. Across facilities, our demonstrates average capture rate 94·95% via N1/PMMoV threshold p ts ≥ 0·5. However, it noteworthy as set higher, such 0·9 or above, model’s reduces 60%. robust performance underscores effectiveness accurately detecting presence cases incarcerated people. Interpretation findings this provide correction public response based on frequent surveillance.

Language: Английский

Citations

0