Laser Interstitial Thermal Therapy for Deep-seated Perivascular Brain Tumors is Not Associated with Distal Ischemia DOI Creative Commons
Jared C. Reese, Hassan Fadel, Jacob Pawloski

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 7, 2023

Abstract Purpose Laser interstitial thermal therapy (LITT) is a minimally invasive cytoreductive treatment option for brain tumors with risk of vascular injury from catheter placement or energy. This may be concern deep-seated that have surrounding end-artery perforators and critical microvasculature. The purpose this study was to assess the distal ischemia following LITT perivascular tumors. Methods A retrospective review multi-institution database used identify patients who underwent between 2013–2022 located within insula, thalamus, basal ganglia, anterior perforated substance. Demographic, clinical volumetric tumor characteristics were collected. primary outcome radiographic evidence on post-ablation magnetic resonance imaging (MRI). Results 61 ablations performed. Of treated, 24 (39%) low-grade gliomas, 32 (52%) high-grade 5 (8%) metastatic. principal location included 31 (51%) insular, 14 (23%) thalamic, 13 (21%) 3 (5%) substance average size 19.6 cm mean ablation volume 11.1 . median extent 92% (IQR 30%, 100%). Two developed symptomatic intracerebral hemorrhage after LITT. No patient had post-operative diffusion weighted imaging. Conclusion We demonstrate has minimal ischemic risks safe otherwise difficult access intracranial

Language: Английский

Laser interstitial thermal therapy for deep-seated perivascular brain tumors is not associated with distal ischemia DOI
Jared C. Reese, Hassan Fadel, Jacob Pawloski

et al.

Journal of Neuro-Oncology, Journal Year: 2024, Volume and Issue: 166(2), P. 265 - 272

Published: Jan. 1, 2024

Language: Английский

Citations

5
Survival outcome and predictors of WHO grade 2 and 3 insular gliomas: A classification based on the tumor spread DOI Creative Commons
Bowen Xue,

Zonggang Hou,

Zhenghai Deng

et al.

Cancer Medicine, Journal Year: 2024, Volume and Issue: 13(11)

Published: June 1, 2024

The study aimed to identify if clinical features and survival outcomes of insular glioma patients are associated with our classification based on the tumor spread.

Language: Английский

Citations

3
Assessing Postoperative Motor Risk in Insular Low‐Grade Gliomas Patients: The Potential Role of Presurgery MRI Corticospinal Tract Shape Measures DOI

Zuocheng Yang,

Fang‐Cheng Yeh, Bowen Xue

et al.

Journal of Magnetic Resonance Imaging, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 23, 2024

Insular low-grade gliomas (LGGs) are surgically challenging due to their proximity critical structures like the corticospinal tract (CST).

Language: Английский

Citations

2
Factors affecting the extent of resection and neurological outcomes following transopercular resection of insular gliomas DOI Creative Commons
Chandrima Biswas, Prakash Shetty, Arpita Sahu

et al.

Acta Neurochirurgica, Journal Year: 2024, Volume and Issue: 166(1)

Published: June 1, 2024

Surgical resection of insular gliomas is a challenge. TO considered more versatile and has lower risk vascular damage. In this study, we aimed to understand the factors that affect rates, ischemic changes neurological outcomes studied utility IONM in patients who underwent for IGs. Retrospective analysis 66 with IG was performed. Radical possible 39% patients. Involvement zone II absence contrast enhancement predicted rate. Persistent deficit rate 10.9%. Although dominant lobe tumors increased immediate fronto-orbital operculum involvement reduced prolonged rate, no tumor related factor showed significant association persistent deficits. 45% developed postoperative infarct, 53% whom Most affected territory lenticulostriate (39%). MEP were observed 9/57 67% stable TcMEPs 74.5% strip MEPs did not develop any motor Long-term deficits seen 3 6% TcMEP respectively. contrast, 25% 50% reversible Tc respectively had DWI clinically relevant when accompanied by intraoperatively, rates three times greater occurred than stable. can be achieved large, multizone IGs, reasonable using approach multimodal intraoperative strategy IONM.

Language: Английский

Citations

2
Gliomas insulares gigantes, una propuesta de manejo quirúrgico DOI Open Access

Stefano Smoquina Montiel

Revista Chilena de Neurocirugía, Journal Year: 2024, Volume and Issue: 49(3), P. 114 - 122

Published: April 11, 2024

Introducción: Los gliomas insulares gigantes (GIG) se definen como aquellos que abarcan las 4 zonas de la clasificación Berger/Sanai. Objetivo: Presentar una casuística 6 para determinar el porcentaje resección tumoral y morbilidad intervención proponer estrategia manejo quirúrgico. Método: Realizamos análisis retrospectivo observacional pacientes con sometidos a tratamiento quirúrgico, en un período 3 años. Resultados: 7 GIG fueron operados entre julio 2019 noviembre 2023. El promedio volumen fue 126,4 ± 36,6 cm3. Se utilizó tractografía (DTI) fMRI 100% los pacientes. La mayoría 2 tiempos, primer abordaje bajo anestesia general cuando glioma era hemisferio no dominante o zona segundo tiempo vigil todos casos. 76,4%, ninguno presentó déficit permanente, debutaron crisis epilépticas 80% mantuvo libre meses. presencia DTI tractos incluidos dentro del tumor activación intra predictor exéresis más limitada. Discusión: En series previas sus volúmenes promedian 76,7 cm3 (17,1-144,1), 72,7% oscila 5,3%-20%. han propuesto distintas estrategias quirúrgicas, involucran cirugia transopercular, monitoreo neurofisiológico transilviana, combinaciones. Conclusión: dos tiempos permite amplia disminuyendo morbilidad. uso cirugía minimizar riesgos afasia motor, estudio preoperatorio puede influir planificación quirúrgica.

Citations

0
Delayed Deep White Matter Ischemia After Resection of Gliomas by Awake Surgery DOI Creative Commons
Takahiro Tsuchiya, Masamichi Takahashi,

Makoto Ohno

et al.

Neurosurgery Open, Journal Year: 2024, Volume and Issue: 5(4)

Published: Aug. 28, 2024

BACKGROUND AND OBJECTIVES: Deep white matter (DWM) is perfused by the medullary arteries from cortex, and ischemia sometimes occurs after glioma resection. However, clinical significance of postoperative artery–related has not been well studied. We retrospectively reviewed cases delayed DWM awake craniotomy to elucidate characteristics, mechanisms, management ischemia. METHODS: identified 4 intra-axial brain tumors, mainly gliomas, that underwent tumor resection at our hospital developed ischemic symptoms surgery, despite no worsening neurological end surgery. RESULTS: Four patients (3 men 1 woman) presented with glioblastoma, oligodendroglioma, astrocytoma, metastasis. The median age surgery was 47.5 years (41-73 years). tumors were located in watershed area frontal lobe ( n = 2) parietal 2), all which left-sided 4). symptoms, such as motor dysfunction, aphasia, dysarthria, dysgraphia, an average 24 hours (14-48 hours) craniotomy. All showed symptom improvement within a week completely recovered month. CONCLUSION: caused sacrifice artery, feeds adjacent tissue during resection, should be considered when aphasia or paralysis postoperatively. These are often transient recovery usually occurs. Tumors lobes, particularly area, carefully monitored for

Language: Английский

Citations

0
Predicting Extent of Resection and Neurological Outcome for Insular Gliomas: An Analysis of Two Available Classifications DOI Open Access
Francesco Guerrini, Viola Marta Custodi,

Antonio Giuri

et al.

Cancers, Journal Year: 2024, Volume and Issue: 16(24), P. 4137 - 4137

Published: Dec. 11, 2024

Background/Objectives: Insular gliomas are rare entities whose surgical resection presents a significant challenge due to their close relationship with crucial white matter bundles and deep perforating arteries. The Berger–Sanai classification is well-established system based on dividing the insula into four quadrants. In contrast, Kawaguchi grading focuses tumor’s behavior vascular infiltration. this study, we compared these two systems in terms of clinical outcomes. Methods: A retrospective single-center consecutive series patients treated for insular was analyzed. Results: total 43 were analyzed, mean age 47 years. average preoperative KPS 92.6, seizures most common presenting symptom. extent (EOR) 92.2%. Both classifications influenced EOR, but former showed moderate-to-strong correlation expected rates. Postoperative outcomes related both systems, association lost at 6-month follow-up. Additionally, lower grades associated postoperative MRI hyperintensities DWI sequences higher rates intraoperative neuromonitoring (IONM) alterations, which translated worse conditions. Conclusions: significantly EOR gliomas; however, only shows strong predictive value regarding serve as good prognostic tools determining short-term outcomes, IONM alterations specifically system.

Language: Английский

Citations

0
Transient olfactory hallucinations after insular glioma surgery: a case report DOI Open Access
Dilshod Mamadaliev, Gayrat Kariev, Ulugbek Asadullaev

et al.

Annals of Medicine and Surgery, Journal Year: 2024, Volume and Issue: 87(1), P. 387 - 392

Published: Dec. 19, 2024

There are various types of hallucinations reported in the literature (auditory, visual, tactile, gustatory, or olfactory), and most them related to psychiatric (schizophrenia) disorders. Olfactory neurosurgical disorders uncommon. The authors present a case patient with left insular glioma who developed transient olfactory after microsurgical resection tumor. Our Objective is share rare postoperative complication-olfactory hallucination following surgery-which can potentially raise awareness among practicing neurosurgeons. A 32-year-old male underwent at our institution 2024. He tumor, which resolved within month postoperatively. Insular gliomas often grow considerable size before becoming symptomatic many patients. region regarded as one brain's sophisticated areas, lesions manifesting wide range symptoms syndromes including hallucinations. neurosurgeons regarding this complication. These complications may resolve short period if no serious vascular injury has been encountered.

Language: Английский

Citations

0
Predicting clinical outcomes of post-operative focal neurological deficits after glioma resection based on MRI characteristics: A retrospective chart review DOI Creative Commons

Syed Sarmad Bukhari,

Faizan Saeed,

Izza Tahir

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Feb. 24, 2023

Abstract Background: The standard of care for gliomas includes maximum safe resection the tumor. This may lead to inadvertent damage tissue directly or vasculature supplying normal brain tissue. result in perilesional infarction which is readily seen on early postoperative MRI scans. Their relationship with presence a deficit and recovery from said unclear. Methods: We did retrospective chart radiology review study this relationship. Results: Out 225 included patients, 24% had infarcts their while rest not have infarcts. incidence new deficits these two groups was significantly different. appear affect against patients no Moreover, location tumor correlate infarcts, deficits. extent also failed show strong correlation Only small percentage all some complete improvement at 6 months follow up. Conclusion: Perilesional are common finding scans after glioma surgery but does help predict nor deficit.

Language: Английский

Citations

0
Laser Interstitial Thermal Therapy for Deep-seated Perivascular Brain Tumors is Not Associated with Distal Ischemia DOI Creative Commons
Jared C. Reese, Hassan Fadel, Jacob Pawloski

et al.

Research Square (Research Square), Journal Year: 2023, Volume and Issue: unknown

Published: Aug. 7, 2023

Abstract Purpose Laser interstitial thermal therapy (LITT) is a minimally invasive cytoreductive treatment option for brain tumors with risk of vascular injury from catheter placement or energy. This may be concern deep-seated that have surrounding end-artery perforators and critical microvasculature. The purpose this study was to assess the distal ischemia following LITT perivascular tumors. Methods A retrospective review multi-institution database used identify patients who underwent between 2013–2022 located within insula, thalamus, basal ganglia, anterior perforated substance. Demographic, clinical volumetric tumor characteristics were collected. primary outcome radiographic evidence on post-ablation magnetic resonance imaging (MRI). Results 61 ablations performed. Of treated, 24 (39%) low-grade gliomas, 32 (52%) high-grade 5 (8%) metastatic. principal location included 31 (51%) insular, 14 (23%) thalamic, 13 (21%) 3 (5%) substance average size 19.6 cm mean ablation volume 11.1 . median extent 92% (IQR 30%, 100%). Two developed symptomatic intracerebral hemorrhage after LITT. No patient had post-operative diffusion weighted imaging. Conclusion We demonstrate has minimal ischemic risks safe otherwise difficult access intracranial

Language: Английский

Citations

0