Phytobiotic effects of Guinea grass supplementation on production and health performances of coloured-broilers DOI Creative Commons
Yee Lyn Ong, Eric Lim Teik Chung, Nazri Nayan

et al.

Italian Journal of Animal Science, Journal Year: 2024, Volume and Issue: 24(1), P. 149 - 163

Published: Dec. 27, 2024

Growing concerns about antibiotic resistance in the livestock industry have prompted researchers to explore alternative solutions. This study investigated effects of Megathyrsus maximus as a phytobiotic supplement on production performance and health Sasso broilers raised tropical environments. 216 mixed-sex broiler chicks were randomly assigned six treatment groups (six replicates per treatment): Treatment 1 (T1) negative control (no antibiotics), 2 (T2) positive (100 mg/kg oxytetracycline), Treatments 3–6 received 1.25, 2.50, 3.75, 5.00 g/kg M. grass meal top basal diet, respectively, without antibiotics. At day 56, T6 had highest final body weight (1.87 kg) superior FCR 1.93. Nutrient digestibility was optimised at higher doses maximus, with CP (67.68%) EE (74.50%) group (p < 0.001). also improved intestinal morphology, VH:CD all segments. However, microbial counts carcase characteristics remained largely unaffected, though meat quality significantly terms reduced drip loss shear force supplementation levels g/kg. Blood biomarkers analysis decreased liver enzyme activity groups, particularly T6, suggests lowered inflammation enhanced function. concludes that supplementation, inclusion level (T6) shows potential an effective replacement poultry production.

Language: Английский

Supplementation of Paraformic Acid as a Substitute for Antibiotics in the Diet Improves Growth Performance and Liver Health in Broiler Chickens DOI Creative Commons

Qinjin Wang,

Jiaxing Niu, Yang Liu

et al.

Animals, Journal Year: 2022, Volume and Issue: 12(20), P. 2825 - 2825

Published: Oct. 18, 2022

The current study aimed to explore the effects of supplementing paraformic acid (PFA) into broilers’ diet on growth performance, inflammatory responses, and liver protection. A total 567 healthy one-day-old broilers were used in a 42-d study, they randomized three groups. Broilers fed basal (CON group) or supplemented with either 50 mg/kg aureomycin (AB 1000 PFA (PFA group). results showed that AB groups had higher feed conversion rate than CON group from day 21 42 (p < 0.05). Dietary supplementation decreased serum levels interleukin (IL)-1β, IL-6, IL-10, alanine transaminase, diamine oxidase, D-lactate, significantly increased concentrations immunoglobulin (Ig) A, IgM, complement C4 Moreover, dietary hepatic caspase-1, NOD-like receptor family pyrin domain containing 3 (NLRP3), tumor necrosis factor-alpha, IL-18, as well NF-κB mRNA expression Above all, improved inhibited benefited protective might be related inhibition caspase-1-induced pyroptosis via inactivating NF-κB/NLRP3 inflammasome axis broiler chickens.

Language: Английский

Citations

4
The combination of macleaya extract and glucose oxidase improves the growth performance, antioxidant capacity, immune function and cecal microbiota of piglets DOI Creative Commons
Xing Chen, Fan Zhang, Huirong Li

et al.

Frontiers in Veterinary Science, Journal Year: 2023, Volume and Issue: 10

Published: July 27, 2023

This study aims to investigate the effects of macleaya extract and glucose oxidase combination (MGO) on growth performance, antioxidant capacity, immune function, cecal microbiota in piglets. A total 120 healthy 28-day-old weaned piglets were randomly divided into two treatments six replicates. Piglets either received a basal diet or supplemented with 250 mg/kg MGO (2 g/kg sanguinarine, 1 chelerythrine, × 106 U/kg oxidase). The results showed that supplementation increased average daily gain (ADG) decreased feed:gain ratio (F/G) (p < 0.05). serum superoxide dismutase (SOD) glutathione peroxidase (GSH-Px) activity, immunoglobulin G (IgG) content 0.05), but malondialdehyde (MDA) interleukin 1β (IL-1β) jejunal mRNA expression nuclear factor erythroid 2-related 2 (Nrf2), (GPX1), heme oxygenase (HO-1) group while kelch like ECH associated protein (Keap1) was Firmicutes significantly at phylum levels In conclusion, improved piglet growth, regulated intestinal flora piglets, which provided theoretical basis for as an alternative additive antibiotics.

Language: Английский

Citations

1
Protective effect of Macleaya cordata isoquinoline alkaloids on lipopolysaccharide-induced liver injury in broilers DOI Creative Commons
Jiaxin Chen, Yang WeiRen, Hua Liu

et al.

Animal Bioscience, Journal Year: 2023, Volume and Issue: 37(1), P. 131 - 141

Published: Nov. 1, 2023

This experiment aimed to explore the protective action of dietary supplementation with isoquinoline alkaloids (IA) from Macleaya cordata on lipopolysaccharide (LPS)-induced liver injury in broilers.

Language: Английский

Citations

1
Macleaya cordata extract improves egg quality by altering gut health and microbiota in laying hens DOI Creative Commons
Guoxin Zhang, Bochen Song, Xue Pan

et al.

Poultry Science, Journal Year: 2024, Volume and Issue: 103(12), P. 104394 - 104394

Published: Oct. 11, 2024

This study investigated the effect of Macleaya cordata extract (MCE) on performance, gut health, and microbiota laying hens. A total 192 thirty-wk-old Hyline brown hens were randomly divided into 4 treatment groups. The CON group received a basal diet, while low (MCE250), medium (MCE350), high (MCE450) dose groups supplemented with 250, 350, 450 mg/kg MCE, respectively. egg weight Haugh unit demonstrated linear quadratic increase MCE during initial 4-wk period experiment (P < 0.05). Furthermore, dietary supplementation led to significant enhancement in eggshell thickness at wk 8 data showed statistically Serum cytokine assay that increases IL-4 IL-10 level Dietary 350 was observed result serum lysozyme levels addition diet resulted sIgA jejunum ileum In terms gene expression, expression IL-10, IgA, Serpinb14, Serpinb14B, OIH jejunal genes pIgR manner, respectively, following IL-1β decreased manner Moreover, these favorable effects maximized dosage (350 mg/kg) addition, intestinal microbial composition control MCE350 assessed. increased relative abundance Bryobacter Parasutterella Erysipelatoclostridium cecum Spearman correlation analysis revealed Bryobacter, Parasutterella, Skermanella, associated nonspecific immune functions conclusion, elevated response, upregulated related protein production eggs, thereby improving quality. These may be changes microbiota, specifically Erysipelatoclostridium.

Language: Английский

Citations

0
Phytobiotic effects of Guinea grass supplementation on production and health performances of coloured-broilers DOI Creative Commons
Yee Lyn Ong, Eric Lim Teik Chung, Nazri Nayan

et al.

Italian Journal of Animal Science, Journal Year: 2024, Volume and Issue: 24(1), P. 149 - 163

Published: Dec. 27, 2024

Growing concerns about antibiotic resistance in the livestock industry have prompted researchers to explore alternative solutions. This study investigated effects of Megathyrsus maximus as a phytobiotic supplement on production performance and health Sasso broilers raised tropical environments. 216 mixed-sex broiler chicks were randomly assigned six treatment groups (six replicates per treatment): Treatment 1 (T1) negative control (no antibiotics), 2 (T2) positive (100 mg/kg oxytetracycline), Treatments 3–6 received 1.25, 2.50, 3.75, 5.00 g/kg M. grass meal top basal diet, respectively, without antibiotics. At day 56, T6 had highest final body weight (1.87 kg) superior FCR 1.93. Nutrient digestibility was optimised at higher doses maximus, with CP (67.68%) EE (74.50%) group (p < 0.001). also improved intestinal morphology, VH:CD all segments. However, microbial counts carcase characteristics remained largely unaffected, though meat quality significantly terms reduced drip loss shear force supplementation levels g/kg. Blood biomarkers analysis decreased liver enzyme activity groups, particularly T6, suggests lowered inflammation enhanced function. concludes that supplementation, inclusion level (T6) shows potential an effective replacement poultry production.

Language: Английский

Citations

0