Folia Microbiologica, Journal Year: 2024, Volume and Issue: 70(1), P. 1 - 17
Published: Aug. 30, 2024
Language: Английский
Animals, Journal Year: 2024, Volume and Issue: 14(7), P. 1087 - 1087
Published: April 3, 2024
Herbal extracts have been widely evaluated in poultry production for their beneficial effects and potential substitute antibiotics, which contribute to AMR risks human health through the consumption of infected meat. Salmonellosis is a systemic infection caused by Salmonella, an intracellular bacterium with ability cause infections significant implications both safety farmers consumers. The excessive use antibiotics has escalated incidence antibiotic resistance bacteria livestock industry, highlighting urgent need alternatives especially meat-type poultry. Both vivo usage vitro studies bioactive compounds from herbal demonstrated effective antimicrobial activities against pathogenic bacteria, showing promise managing Salmonella enhancing performance. Phytobiotic feed additives shown promising results improving output due pharmacological properties, such as stimulating consumption, antioxidant properties preventing increasing threats. Despite synergistic plant-derived compounds, further investigation into essential fully understand role mechanisms action, developing delivery systems, assessing environmental sustainability controlling production.
Language: Английский
Citations
7
Published: Jan. 1, 2025
Some essential oils (EOs) have exhibited high efficacy against Salmonella Typhimurium, suggesting that specific molecular structures within their constituents could inform the development of alternative antimicrobial agents, potentially addressing rise antibiotic resistance in this bacterium. Through feature permutation analysis on a dataset 171 EO samples encompassing 682 substructures, we identified ten key predictors antibacterial activity S. Typhimurium. These were used to train logistic regression-based machine learning model. Hydroxyl-substituted benzene rings characteristic phenolic compounds - such as carvacrol, thymol and eugenol emerged strong activity. In contrast, non-aromatic bicyclic present monoterpenoids like alpha-pinene, beta-pinene delta-3-carene associated with lack Salmonella. The features align existing research properties compounds, thereby validating use approaches guiding discovery naturally occurring agents.
Language: Английский
Citations
0
Animals, Journal Year: 2025, Volume and Issue: 15(6), P. 875 - 875
Published: March 19, 2025
This mini-review presents common strategies for controlling Salmonella in poultry, addressing combined pre-harvest and post-harvest interventions to create a multi-hurdle approach. The goal is highlight integrated approaches that enhance overall food safety sustainability within the poultry industry. Current are discussed, including industry practices regulatory frameworks. Emphasis placed on implementation of biosecurity measures, vaccination, feed management, environmental control settings, as well processing plant such antimicrobials carcass decontamination, sanitation, quality measures. Pre-harvest have shown promise include enhanced protocols, selective vaccinations pathogenic strains, advanced feeding regimens. Post-harvest interventions, antimicrobial application improved sanitation practices, pathogen reduction technologies also critical reducing prevalence. An approach combines both measures essential an effective program. Implementing continuum production vital ensuring protecting public health. Collaborative efforts between researchers, stakeholders, policymakers necessary address emerging issues effectiveness.
Language: Английский
Citations
0
Veterinary Sciences, Journal Year: 2023, Volume and Issue: 10(12), P. 706 - 706
Published: Dec. 15, 2023
Restrictions on the use of antimicrobial compounds have led to a surge interest in alternative solutions, such as natural, plant-based compounds. In our study, we investigated efficacy three feed supplements containing different additives, namely, probiotics (Lactobacillus spp., "Test substance A"), turmeric (Curcuma longa L., B"), and fenugreek (Trigonella foenum graecum, C"). experiment, tested 180 birds Bábolna Tetra-SL laying hybrid breed that were infected with Salmonella enteritidis strains. The randomly divided into six groups: groups treated negative control group, positive an antibiotic-treated group using enrofloxacin. We examined maturation time course shedding Salmonella; at end rearing, pathological histopathological examinations performed. When was isolated from cloacal swab samples, enrofloxacin-treated had high number animals by day 9, which like test material C. greatest reduction observed materials A B. terms parameters, villus length crypt depth significantly better C compared controls, when comparing body weight animals, B larger absorption surface area group. Overall, supplement proved be most effective. future, it is worthwhile investigate combination active substances for their possible synergistic effects perform dose-response study select optimal dosage.
Language: Английский
Citations
9
Microorganisms, Journal Year: 2024, Volume and Issue: 12(12), P. 2612 - 2612
Published: Dec. 17, 2024
Salmonella infections in poultry production are a significant and pervasive concern, posing substantial risks to both animal human health. This comprehensive literature review examines the current body of research on use various nutritional manipulations as promising strategy effectively control mitigate prevalence poultry. The covers range dietary interventions, particularly utilization probiotics, prebiotics, organic acids, phytochemicals, thoroughly evaluates their efficacy reducing colonization within flocks. Furthermore, delves into potential underlying mechanisms action for these approaches far-reaching implications overall food safety. By providing thorough analysis existing literature, this aims elucidate most strategies that can be employed production, ultimately safeguarding welfare public
Language: Английский
Citations
1
Antibiotics, Journal Year: 2024, Volume and Issue: 13(10), P. 932 - 932
Published: Oct. 1, 2024
Background: Beef burgers are perishable meat products, and to extend their shelf life, EU Regulation 1129/11 permits the use of certain additives. Objectives: However, given concerns health-conscious consumers potential toxicity synthetic substances, this study aimed explore fennel waste extracts as natural preservatives. Methods: This characterized bioactive compounds (phenolic content), antioxidant activity (ABTS+ DPPH assay), antimicrobial properties (against Salmonella enterica serotype Enteritidis, Escherichia coli, Staphylococcus aureus, Bacillus cereusi, Pseudomonas aeruginosa) different (LF, liquid fraction; SF, solid fraction PF, pellet fraction). Additionally, best extract was evaluated for its impact on beef burger life (up 18 days at 4 ± 1 °C) in terms microbiological profile, pH, water (aw). Results: The PF extract, which rich flavones, hydroxybenzoic, hydroxycinnamic acids, demonstrated highest activities. Microbiological analyses with identified a substance. aw pH values did not appear be affected. Conclusions: In conclusion, could proposed exploitable preserve quality shelf-life.
Language: Английский
Citations
1
Journal of Pharmacognosy and Phytochemistry, Journal Year: 2023, Volume and Issue: 12(5), P. 256 - 263
Published: Jan. 1, 2023
Traditional medicines such as Azadirachta indica (A. indica) possess medicinal properties that should be explored in drug discovery to combat infectious diseases and antimicrobial resistance. This study provided insights into the antibacterial activities of A. indica. narrative review utilised Google Scholar PubMed search for articles were published from January 2000 September 2023 on The found has activity against Escherichia coli, Staphylococcus aureus, Enterococcus faecalis, other bacteria. reported due its phytochemical content phenolics, tannins, saponins, flavonoids, terpenoids, fatty acids, alkaloids. some Gram-negative Gram-positive bacteria presence phytochemicals. There is a need increase investment integration traditional medicine healthcare system.
Language: Английский
Citations
3
Foods, Journal Year: 2024, Volume and Issue: 13(4), P. 584 - 584
Published: Feb. 15, 2024
Antibiotic resistance in foodborne pathogens is an increasing threat to global human health. Among the most prevalent antibiotic-resistant bacteria are Salmonella enterica serovar Typhimurium, Campylobacter jejuni and E. coli 0157:H7. Control of these other requires innovative approaches, i.e., discovering new molecules that will inactivate them, or render them less virulent without inducing resistance. Recently, several polyphenol have been shown possess such characteristics. Also, use CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) approaches has recently proposed for purpose. This review summarizes main findings regarding application both control above-mentioned by relying on Quorum Sensing interference (Quorum Quenching) mechanisms highlights avenues needed further research.
Language: Английский
Citations
0
Published: Jan. 1, 2024
Language: Английский
Citations
0
International Immunopharmacology, Journal Year: 2024, Volume and Issue: 142, P. 113163 - 113163
Published: Sept. 19, 2024
Language: Английский
Citations
0