PLoS neglected tropical diseases, Journal Year: 2025, Volume and Issue: 19(4), P. e0013029 - e0013029

Published: April 23, 2025

Cholera is a virulent infectious disease caused by the Gram-negative, comma-shaped bacteria Vibrio cholerae , after ingesting contaminated food and/or water. If left untreated, it can kill within 5 days. Since mid-2021 world has recorded notable increase in seventh cholera pandemic, with high case fatality rate especially Sub-Saharan Africa. Oral vaccines are established but not readily available on market, or if they are, pocket friendly for low-resource-income countries. Hence, advent of green factory biotechnology, plant-derived edible such promising approach to supplement conventional vaccine methods. Human travellers often major transmitters as move from region region. Poor sanitation and inadequate clean water supply services most African countries, coupled insufficient surveillance services, lack early detection facilities, public having ample awareness concerning hygiene. This article highlights epidemiology Africa expounds what drives outbreaks this The discussion provides an in-depth analysis factors leading forsaken drivers, emphasizing economic factors, culture, environmental influences, particularly communities. It presents strategic blueprint that includes health awareness, community participation, government involvement, exploring emerging research tools. By merging these proposals into unified context, collective practical methodology would be tackle impact been sidelined

Language: Английский