Allogeneic Islet Transplantation: Chronicle of a Death Foretold? DOI Creative Commons
Thierry Berney, Olivier Thaunat, Ekaterine Berishvili

et al.

Transplant International, Journal Year: 2025, Volume and Issue: 38

Published: April 1, 2025

Innovative solutions have entered the routine management of patients with type 1 diabetes or are making headlines and this is shaking world beta cell replacement therapies. Above all, allogeneic islet transplantation enthusiastically doomed to extinction by aficionados "closed loop" artificial insulin delivery systems those convinced imminent large scale availability stem-cell derived insulin-producing tissues. This opinion paper will propose that neither be a universal solution in very near future argue xenogeneic may serious outsider race for new In meantime, odds favor (and pancreas) remaining first line options treatment complicated diabetes. There no question already greatly improved diabetes, but, while "unlimited" sources cells jockeying approval as standard-of-care, these improvements more likely drive shift indications -from transplant alone simultaneous islet-kidney transplantation- than herald demise transplantation.

Language: Английский

Allogeneic Islet Transplantation: Chronicle of a Death Foretold? DOI Creative Commons
Thierry Berney, Olivier Thaunat, Ekaterine Berishvili

et al.

Transplant International, Journal Year: 2025, Volume and Issue: 38

Published: April 1, 2025

Innovative solutions have entered the routine management of patients with type 1 diabetes or are making headlines and this is shaking world beta cell replacement therapies. Above all, allogeneic islet transplantation enthusiastically doomed to extinction by aficionados "closed loop" artificial insulin delivery systems those convinced imminent large scale availability stem-cell derived insulin-producing tissues. This opinion paper will propose that neither be a universal solution in very near future argue xenogeneic may serious outsider race for new In meantime, odds favor (and pancreas) remaining first line options treatment complicated diabetes. There no question already greatly improved diabetes, but, while "unlimited" sources cells jockeying approval as standard-of-care, these improvements more likely drive shift indications -from transplant alone simultaneous islet-kidney transplantation- than herald demise transplantation.

Language: Английский

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