Sex- and Gender-Specific Considerations in Mycotoxin Screening: Assessing Differential Exposure, Health Impacts, and Mitigation Strategies DOI Creative Commons
Gayathree Thenuwara, Bilal Javed, Baljit Singh

et al.

Microbiology Research, Journal Year: 2024, Volume and Issue: 15(4), P. 2455 - 2492

Published: Nov. 29, 2024

Mycotoxins, toxic secondary metabolites produced by fungi, present significant health risks through contaminated food and feed. Despite broad documentation of their general impacts, emerging research highlights the requirement addressing both sex- gender-specific differences in risk exposure, susceptibility, outcomes mycotoxin screening mitigation strategies. Distinct biological (sex-based) sociocultural (gender-based) factors can influence exposure subsequent impacts; women may for example exhibit specific exposures to certain mycotoxins due physiological hormonal differences, with increased during critical life stages such as pregnancy lactation. Conversely, men demonstrate distinct metabolic immune responses these toxins. Socioeconomic cultural also contribute risks, including occupational exposures, dietary habits, healthcare access. Current methodologies regulatory frameworks often disregard sex gender disparities, resulting incomplete assessments suboptimal public interventions. This review addresses incorporation data into research, development advanced techniques, implementation targeted Addressing is crucial enhancing efficacy management policies safeguarding health. Future directions policy recommendations are discussed promote a more comprehensive practical approach assessment control.

Language: Английский

Sex- and Gender-Specific Considerations in Mycotoxin Screening: Assessing Differential Exposure, Health Impacts, and Mitigation Strategies DOI Creative Commons
Gayathree Thenuwara, Bilal Javed, Baljit Singh

et al.

Microbiology Research, Journal Year: 2024, Volume and Issue: 15(4), P. 2455 - 2492

Published: Nov. 29, 2024

Mycotoxins, toxic secondary metabolites produced by fungi, present significant health risks through contaminated food and feed. Despite broad documentation of their general impacts, emerging research highlights the requirement addressing both sex- gender-specific differences in risk exposure, susceptibility, outcomes mycotoxin screening mitigation strategies. Distinct biological (sex-based) sociocultural (gender-based) factors can influence exposure subsequent impacts; women may for example exhibit specific exposures to certain mycotoxins due physiological hormonal differences, with increased during critical life stages such as pregnancy lactation. Conversely, men demonstrate distinct metabolic immune responses these toxins. Socioeconomic cultural also contribute risks, including occupational exposures, dietary habits, healthcare access. Current methodologies regulatory frameworks often disregard sex gender disparities, resulting incomplete assessments suboptimal public interventions. This review addresses incorporation data into research, development advanced techniques, implementation targeted Addressing is crucial enhancing efficacy management policies safeguarding health. Future directions policy recommendations are discussed promote a more comprehensive practical approach assessment control.

Language: Английский

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