Molecular diagnosis of Trypanosomatids in Didelphis marsupialis reveals risk areas for Trypanosoma cruzi transmission and sympatric circulation with T. rangeli in the metropolitan area of Bucaramanga, Santander, Colombia DOI Creative Commons
Jeiczon Jaimes-Dueñez,

Vladimir Quintero-Sánchez,

Andrea Ardila-Gélvez

et al.

International Journal for Parasitology Parasites and Wildlife, Journal Year: 2025, Volume and Issue: unknown, P. 101072 - 101072

Published: April 1, 2025

Language: Английский

Tick Control Strategies: Critical Insights into Chemical, Biological, Physical, and Integrated Approaches for Effective Hard Tick Management DOI Creative Commons
Tsireledzo Goodwill Makwarela, Nimmi Seoraj-Pillai, Tshifhiwa C. Nangammbi

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(2), P. 114 - 114

Published: Feb. 2, 2025

Ticks and tick-borne diseases significantly impact animal health, public economic productivity globally, particularly in areas where the wildlife–livestock interface complicates management. This review critically examines current control strategies, focusing on chemical, biological, physical, integrated pest management (IPM) approaches. Chemical acaricides, while effective, are increasingly challenged by resistance development environmental concerns. Biological approaches, including natural predators entomopathogenic fungi, physical interventions, such as habitat modification, provide sustainable alternatives but require further optimization. IPM stands out most promising long-term solution, integrating multiple approaches to enhance efficacy reducing risks. Emerging innovations, nanotechnology-enhanced acaricides next-generation vaccines, offer avenues for improved tick control. Addressing complex challenges of requires tailored interdisciplinary collaboration, sustained research investment both veterinary health contexts.

Language: Английский

Citations

3

Comprehensive Insights into Highly Pathogenic Avian Influenza H5N1 in Dairy Cattle: Transmission Dynamics, Milk-Borne Risks, Public Health Implications, Biosecurity Recommendations, and One Health Strategies for Outbreak Control DOI Creative Commons

Henrietta Owusu,

Yasser M. Sanad

Pathogens, Journal Year: 2025, Volume and Issue: 14(3), P. 278 - 278

Published: March 13, 2025

Highly pathogenic avian influenza (HPAI) H5N1 has been traditionally linked to poultry and wild birds, which recently become a serious concern for dairy cattle, causing outbreaks all over the United States. The need improved surveillance, biosecurity protocols, interagency collaboration is highlighted by discovery of in herds several states its human transmission. epidemiology, transmission dynamics, wide-ranging effects cattle are reviewed this paper, with particular attention paid disease’s on agricultural systems, public health, animal health. Nonspecific clinical symptoms, such as decreased milk production irregular consistency, indicative infection cows. Alarmingly, significant virus loads have discovered raw milk, raising worries about potential zoonotic dangers viral spillover between species further cases domestic cats experiencing severe neurological symptoms after ingesting colostrum from infected Even though remain rare, they mostly related occupational exposure, constant required due possibility adaptability. necessity One Health approach that integrates environmental, animal, health efforts supported broad occurrence across multiple species. For early detection, containment, mitigation, cooperation veterinary clinics, organizations, stakeholders crucial. Controlling outbreak requires stringent movement restrictions, regular testing cows reference labs, adherence procedures. This review highlights importance thorough coordinated manage combining existing knowledge pointing out gaps surveillance response strategies. Additionally, it sheds light risk consumption cow’s contaminated humans other companion animals like cats. In face changing threat, proactive monitoring, strict cross-sector crucial reducing financial losses protecting

Language: Английский

Citations

1

Role of interferons in the antiviral battle: from virus-host crosstalk to prophylactic and therapeutic potential in SARS-CoV-2 infection DOI Creative Commons

Grigore Mihăescu,

Mariana Carmen Chifiriuc, Roxana Filip

et al.

Frontiers in Immunology, Journal Year: 2024, Volume and Issue: 14

Published: Jan. 15, 2024

Mammalians sense antigenic messages from infectious agents that penetrate the respiratory and digestive epithelium, as well signals damaged host cells through membrane cytosolic receptors. The transduction of these triggers a personalized response, depending on nature stimulus host’s genetics, physiological condition, comorbidities. Interferons (IFNs) are primary effectors innate immune their synthesis is activated in most within few hours after pathogen invasion. IFNs primarily synthesized infected cells, but anti-infective effect extended to neighboring by autocrine paracrine action. emergence severe acute syndrome coronavirus 2 (SARS‐CoV‐2) pandemic 2019 was stark reminder potential threat posed newly emerging viruses. This has also triggered an overwhelming influx research studies aiming unveil mechanisms protective versus pathogenic responses induced SARS‐CoV‐2. purpose this review describe role vital players battle against SARS‐CoV-2 infection. We will briefly characterize classify IFNs, present inductors IFN synthesis, sensors, signaling pathways, then discuss controlling evolution SARS-CoV-2 infection its clinical outcome. Finally, we perspectives controversies regarding prophylactic therapeutic

Language: Английский

Citations

8

One World, One Health: Zoonotic Diseases, Parasitic Diseases, and Infectious Diseases DOI Open Access
Giovanna Deiana, Antonella Arghittu, Marco Dettori

et al.

Healthcare, Journal Year: 2024, Volume and Issue: 12(9), P. 922 - 922

Published: April 29, 2024

When we take into account how the boundaries between human, animal, and environmental health are inextricably linked increasingly intertwined, it comes as no surprise that One Health approach has assumed an unprecedented level of importance over past decade [...]

Language: Английский

Citations

6

Significance of Artificial Intelligence in the Study of Virus–Host Cell Interactions DOI Creative Commons
James Elste,

Akash Saini,

Rafael Mejía-Alvarez

et al.

Biomolecules, Journal Year: 2024, Volume and Issue: 14(8), P. 911 - 911

Published: July 26, 2024

A highly critical event in a virus's life cycle is successfully entering given host. This process begins when viral glycoprotein interacts with target cell receptor, which provides the molecular basis for virus-host interactions novel drug discovery. Over years, extensive research has been carried out field of interaction, generating massive number genetic and data sources. These datasets are an asset predicting at level using machine learning (ML), subset artificial intelligence (AI). In this direction, ML tools now being applied to recognize patterns these predict between virus host cells protein-protein protein-sugar levels, as well perform transcriptional translational analysis. On other end, deep (DL) algorithms-a subfield ML-can extract high-level features from very large hidden within genomic sequences images develop models rapid discovery predictions that address pathogenic viruses displaying heightened affinity receptor docking enhanced entry. DL pivotal forces, driving innovation their ability analysis enormous efficient, cost-effective, accurate, high-throughput manner. review focuses on complexity light current advances AI pathogenesis improve new treatments prevention strategies.

Language: Английский

Citations

6

Minimal zoonotic risk of cryptosporidiosis and giardiasis from frogs and reptiles DOI Creative Commons
Siobhon Egan, Amanda D. Barbosa, Yaoyu Feng

et al.

European Journal of Protistology, Journal Year: 2024, Volume and Issue: 93, P. 126066 - 126066

Published: Feb. 28, 2024

The zoonotic potential of the protist parasites Cryptosporidium spp. and Giardia duodenalis in amphibians reptiles raises public health concerns due to their growing popularity as pets. This review examines prevalence diversity these wild captive better understand risk. Research on both groups is limited, forms or have not been reported amphibians. Host-adapted species dominate reptiles, albeit some found carry (C. hominis C. parvum) rodent-associated tyzzeri, muris andersoni) species, primarily through mechanical carriage. Similarly, limited reports (assemblages A, B E) may also be Thus, available evidence indicates minimal risk associated with organisms frogs reptiles. exact transmission routes for infections within reptile populations remain poorly understood, particularly regarding importance Although appears minimal, continued research surveillance efforts are necessary gain a more comprehensive understanding dynamics ultimately improve our ability safeguard human animal health.

Language: Английский

Citations

5

Intersecting realities: Exploring the nexus between armed conflicts in eastern Democratic Republic of the Congo and Global Health DOI Creative Commons
Olivier Kambere Kavulikirwa

One Health, Journal Year: 2024, Volume and Issue: 19, P. 100849 - 100849

Published: July 3, 2024

The eastern Democratic Republic of the Congo (DRC) grapples with entrenched armed conflicts, creating a complex humanitarian crisis far-reaching implications for global health. This paper explores intersection between conflict in region and risks zoonotic disease transmission, shedding light on interconnected challenges proposing integrated strategies mitigation. Armed disrupts healthcare systems, affecting facilities (HCF) workers (HCW), destroying millions lives, impoverishing communities, weakening surveillance systems. deleterious situation is bottleneck to achieving Sustainable Development Goals (SDGs), especially Universal Health Coverage (UHC), as it prevents Congolese from accessing services. direct impact insecurity undermines Global Security (GHS) by fostering natural habitat degradation biodiversity loss, exacerbating vulnerabilities outbreaks. Forced population displacement encroachment habitats amplify human-wildlife interaction, facilitating spillover increasing risk regional spread. Biodiversity loss poaching further compound these challenges, underscoring need holistic approaches that address both conservation public health concerns. Mitigating requires strengthening promoting community engagement, integrating efforts resolution initiatives. By adopting comprehensive approach, including incorporation One considerations all peace-seeking efforts, stakeholders can enhance Security, scale up UHC, promote sustainable development conflict-affected regions. Creativity strategic foresight are essential safeguarding well-being human, livestock, plant, wildlife populations Eastern DRC.

Language: Английский

Citations

4

Mitigating Tick-Borne Virus Threats in the Middle East: A Biosafety and One Health Approach DOI
Laith N. AL‐Eitan, Haneen Ali, Hana Abu Kharmah

et al.

Current Tropical Medicine Reports, Journal Year: 2025, Volume and Issue: 12(1)

Published: Feb. 24, 2025

Language: Английский

Citations

0

Climate Change Unveils Hidden Microbial Dangers DOI Creative Commons
Haoxuan Yu

Environmental Science and Ecotechnology, Journal Year: 2025, Volume and Issue: 24, P. 100544 - 100544

Published: Feb. 27, 2025

Language: Английский

Citations

0

Epidemiology DOI
Ismail Ayoade Odetokun, Aminu Shittu,

Akeem Adebola Bakare

et al.

Published: March 21, 2025

Citations

0