Changes in social environment impact primate gut microbiota composition DOI Creative Commons

Charles Pearce,

Danielle L. Bukovsky,

Katya Douchant

et al.

Animal Microbiome, Journal Year: 2024, Volume and Issue: 6(1)

Published: Nov. 13, 2024

The gut microbiota (GM) has proven to be essential for both physical health and mental wellbeing, yet the forces that ultimately shape its composition remain opaque. One critical force known affect GM is social environment. Prior work in humans free-ranging non-human primates shown cohabitation frequent interaction can lead changes composition. However, it difficult assess direction of causation these studies, interpretations are complicated by influence uncontrolled but correlated factors, such as shared diet. We performed a 15-month longitudinal investigation wherein we disentangled impacts diet living conditions on captive cohort 13 male cynomolgus macaques. animals were single housing first 3 months study initially with variable After baseline data collection they placed controlled remainder study. Following this shift moved paired 6 months, enabling enhanced interaction, then subsequently returned at end our This structured sequencing allowed us their distinct found early dietary adjustments led alpha beta diversity, whereas only altered diversity. With respect latter, two particular bacterial families — Lactobacillaceae Clostridiaceae demonstrated significant shifts abundance during transition from housing, which was observed based change Conversely, other bacteria previously associated sociality not rather Together, findings decouple influences have reconcile previous observations human animal literatures. Moreover, results indicate biological alterations may, part, mediate relationship between wellbeing.

Language: Английский

Multi-omics insights into the response of the gut microbiota and metabolites to albendazole deworming in captive Rhinopithecus brelichi DOI Creative Commons
Xue Qin,

Jincheng Han,

Xi Li

et al.

Frontiers in Microbiology, Journal Year: 2025, Volume and Issue: 16

Published: April 23, 2025

Background Parasite infection and deworming treatment affect the host gut microbiota. Exploring response mechanism of microbiota in Rhinopithecus brelichi ( R. ) to albendazole is great value for protecting this critically endangered species. Methods results This study used metataxonomics metabolomics explore responses metabolites treatment. The showed that significantly reduced eggs per gram feces (EPG). 16S rRNA gene sequencing richness diversity after were increased. Meanwhile, also changed composition At genus level, Christensenellaceae R7 group , UCG 002 005 uncultured rumen bacterium Rikenellaceae RC9 enriched pre-deworming samples. Unclassified Muribaculaceae Prevotella 9 Bacteroides post-deworming Metabolomics analysis revealed relative abundance 382 out 1,865 significant differences between pre- Among them, 103 annotated based on HMDB mainly classified into Prenol lipids, Carboxylic acids derivatives, Organooxygen compounds, etc. KEGG enrichment result indicated these involved energy, amino acid, lipid, purine metabolism. Correlation unclassified whose abundances upregulated treatment, positively correlated with Kaempferol, 5,7-Dihydroxy-3-methoxy-4′-prenyloxyflavone, Purpurin, Rhein, which have anti-parasitic activities. a downregulated was not only negatively above four metabolites, but Retinyl beta-glucuronide, storage form vitamin A, CDP-Choline, increases host’s susceptibility Entamoeba histolytica Plasmodium falciparum . Conclusion emphasizes has an impact metabolic functions By exploiting correlations differential potential probiotics or prebiotics can be explored, thereby enhancing efficiency reducing its side effects.

Language: Английский

Citations

0
Analysis of winter diet in Guizhou golden monkey (Rhinopithecus brelichi) using DNA metabarcoding data DOI Creative Commons
Xu Zhang,

Huafu Zhong,

Jingcheng Ran

et al.

Ecology and Evolution, Journal Year: 2024, Volume and Issue: 14(2)

Published: Feb. 1, 2024

Abstract The Guizhou golden monkey ( Rhinopithecus brelichi ) is a critically endangered wildlife species, and understanding its diet composition may be useful for assessing feeding strategies. DNA metabarcoding was used to determine the dietary diversity of R. . extracted from 31 faecal samples amplified chloroplast rbcL mitochondrial COI sequenced using Illumina NovaSeq platform. A comparative analysis sequences revealed that five most abundant plant genera were Magnolia , Morinda Viburnum Tetradium Eurya In winter, mostly consumed shrubs, herbs shrubs/trees according habit with higher abundances comparatively. families in animal Psychodidae, Trichinellidae, Staphylinidae, Scarabaeidae Trichoceridae. This study first show winter diets based on metabarcoding. These results provide an important basis wild which inhabits only Fanjingshan National Nature Reserve, China.

Language: Английский

Citations

3
Interspecific associations between <i>Rhinopithecus brelichi</i> and its sympatric species using infrared cameras DOI Open Access

Huang Xiaolong,

Meng Bingshun,

LI Hai-bo

et al.

Biodiversity Science, Journal Year: 2024, Volume and Issue: 32(2), P. 23402 - 23402

Published: Jan. 1, 2024

生态学作用及其保护问题。结果表明: (1)黔金丝猴与藏酋猴(Macaca thibetana)、红腹角雉(Tragopan temminckii)、中华鬣羚 (Capricornis milneedwardsii)、食蟹獴(Herpestes urva)、马来豪猪(Hystrix brachyura)、猪獾(Arctonyx collaris)、野猪(Sus scrofa)、 勺鸡(Pucrasia macrolopha)和小麂(Muntiacus reevesi)存在空间关联, 其所处群落的物种组成与川金丝猴(Rhinopithecus roxellana)较为相似。(

Citations

1
Protecting Endangered Animal Species DOI Creative Commons

Chunwang Li

Animals, Journal Year: 2024, Volume and Issue: 14(18), P. 2644 - 2644

Published: Sept. 12, 2024

Currently, global biodiversity loss is a growing problem, and more species are endangered at risk of extinction [...].

Language: Английский

Citations

0
Changes in social environment impact primate gut microbiota composition DOI Creative Commons

Charles Pearce,

Danielle L. Bukovsky,

Katya Douchant

et al.

Animal Microbiome, Journal Year: 2024, Volume and Issue: 6(1)

Published: Nov. 13, 2024

The gut microbiota (GM) has proven to be essential for both physical health and mental wellbeing, yet the forces that ultimately shape its composition remain opaque. One critical force known affect GM is social environment. Prior work in humans free-ranging non-human primates shown cohabitation frequent interaction can lead changes composition. However, it difficult assess direction of causation these studies, interpretations are complicated by influence uncontrolled but correlated factors, such as shared diet. We performed a 15-month longitudinal investigation wherein we disentangled impacts diet living conditions on captive cohort 13 male cynomolgus macaques. animals were single housing first 3 months study initially with variable After baseline data collection they placed controlled remainder study. Following this shift moved paired 6 months, enabling enhanced interaction, then subsequently returned at end our This structured sequencing allowed us their distinct found early dietary adjustments led alpha beta diversity, whereas only altered diversity. With respect latter, two particular bacterial families — Lactobacillaceae Clostridiaceae demonstrated significant shifts abundance during transition from housing, which was observed based change Conversely, other bacteria previously associated sociality not rather Together, findings decouple influences have reconcile previous observations human animal literatures. Moreover, results indicate biological alterations may, part, mediate relationship between wellbeing.

Language: Английский

Citations

0