Primary Cell Culture as a Model System for Evolutionary Molecular Physiology

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(14), P. 7905 - 7905

Published: July 19, 2024

Primary cell culture is a powerful model system to address fundamental questions about organismal physiology at the cellular level, especially for species that are difficult, or impossible, study under natural semi-natural conditions. Due their ease of use, primary fibroblast cultures dominant system, but studies using both somatic and germ cells also common. Using these models, genome evolution phylogenetic relationships, molecular biochemical basis differential longevities among species, physiological consequences life history have been studied in depth. With advent new technologies such as gene editing generation induced pluripotent stem (iPSC), field evolutionary will continue expand descriptive experimental approaches.

Language: Английский

Induced Pluripotent Stem Cells in Birds: Opportunities and Challenges for Science and Agriculture

Veterinary Sciences, Journal Year: 2024, Volume and Issue: 11(12), P. 666 - 666

Published: Dec. 19, 2024

The only cells in an organism that could do any other sort of cell until 2006 (except sperm or egg) were known as embryonic stem cells, ESC [...]

Language: Английский