Integrated Microbiome and Metabolomics Analysis Reveals Altered Aggressive Behaviors in Broiler Chickens Showing Different Tonic Immobility DOI Creative Commons
Jiang Gao,

Xiaoxian Cheng,

Xuanfu Wu

et al.

Animals, Journal Year: 2025, Volume and Issue: 15(4), P. 601 - 601

Published: Feb. 19, 2025

Tonic immobility (TI) serves as an indicator of innate stress response recovery in poultry. Broilers with different TI phenotypes exhibit varying levels aggressive behavior, which can significantly impact their welfare. However, the influences on broiler aggression remain largely unexplored. In this study, chickens were stratified into two distinct phenotypic groups based duration: short (STI) and long (LTI). The impacts investigated by analyzing cecal intestinal morphology, bacteria, plasma metabolites, corticosterone levels. Compared to LTI broilers, STI broilers showed reduced (CORT) (p < 0.05) a decreased frequency behaviors, including dominant subdominant types 0.01). Histological analysis revealed that have increased duodenal villus height villus-height-to-crypt-depth ratio 0.01), jejunal crypt depth ileal 0.01) compared broilers. 16S rDNA sequencing Linear discriminant effect size (LefSe) identified differential bacterial abundance, notably genus cc115 belonging Firmicutes. Specific microbiota exhibited significant positive correlations behavior corticosterone, while those negative correlations. Untargeted metabolomics 21 downregulated 17 upregulated metabolites between phenotypes. Correlation 10 positively correlated whereas 8 negatively correlated. higher content more intense than behavioral physiological profiles observed are strongly specific gut metabolite profiles. microbial signatures serve key biomarkers for regulating represent potential early indicators detecting issues poultry farming.

Language: Английский

Integrated Microbiome and Metabolomics Analysis Reveals Altered Aggressive Behaviors in Broiler Chickens Showing Different Tonic Immobility DOI Creative Commons
Jiang Gao,

Xiaoxian Cheng,

Xuanfu Wu

et al.

Animals, Journal Year: 2025, Volume and Issue: 15(4), P. 601 - 601

Published: Feb. 19, 2025

Tonic immobility (TI) serves as an indicator of innate stress response recovery in poultry. Broilers with different TI phenotypes exhibit varying levels aggressive behavior, which can significantly impact their welfare. However, the influences on broiler aggression remain largely unexplored. In this study, chickens were stratified into two distinct phenotypic groups based duration: short (STI) and long (LTI). The impacts investigated by analyzing cecal intestinal morphology, bacteria, plasma metabolites, corticosterone levels. Compared to LTI broilers, STI broilers showed reduced (CORT) (p < 0.05) a decreased frequency behaviors, including dominant subdominant types 0.01). Histological analysis revealed that have increased duodenal villus height villus-height-to-crypt-depth ratio 0.01), jejunal crypt depth ileal 0.01) compared broilers. 16S rDNA sequencing Linear discriminant effect size (LefSe) identified differential bacterial abundance, notably genus cc115 belonging Firmicutes. Specific microbiota exhibited significant positive correlations behavior corticosterone, while those negative correlations. Untargeted metabolomics 21 downregulated 17 upregulated metabolites between phenotypes. Correlation 10 positively correlated whereas 8 negatively correlated. higher content more intense than behavioral physiological profiles observed are strongly specific gut metabolite profiles. microbial signatures serve key biomarkers for regulating represent potential early indicators detecting issues poultry farming.

Language: Английский

Citations

0