Preserving Fossilized Soft Tissues: Advancing Proteomics and Unveiling the Evolutionary History of Cancer in Dinosaurs DOI Creative Commons
Pramodh Chandrasinghe, Biancastella Cereser, Sérgio Bertazzo

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(4), P. 370 - 370

Published: April 3, 2025

Understanding how life-history strategies influence cancer susceptibility in dinosaurs requires a molecular-level analysis of preserved soft tissues. While previous research has largely focused on skeletal remains, the discovery tissue structures fossils, such as Telmatosaurus transsylvanicus, highlights need for new approach. Paleoproteomics offers transformative opportunity to analyze ancient proteins, revealing evolutionary trade-offs between growth, reproduction, and suppression. This study argues that prioritizing fossil collection preservation is crucial, future advances molecular techniques will allow deeper insights into disease evolution. By integrating theory with paleopathology, we can better understand selective pressures shaped extinct species identify potential mechanisms tumor resistance. commentary necessity long-term conservation efforts support breakthroughs biology comparative oncology.

Language: Английский

Preserving Fossilized Soft Tissues: Advancing Proteomics and Unveiling the Evolutionary History of Cancer in Dinosaurs DOI Creative Commons
Pramodh Chandrasinghe, Biancastella Cereser, Sérgio Bertazzo

et al.

Biology, Journal Year: 2025, Volume and Issue: 14(4), P. 370 - 370

Published: April 3, 2025

Understanding how life-history strategies influence cancer susceptibility in dinosaurs requires a molecular-level analysis of preserved soft tissues. While previous research has largely focused on skeletal remains, the discovery tissue structures fossils, such as Telmatosaurus transsylvanicus, highlights need for new approach. Paleoproteomics offers transformative opportunity to analyze ancient proteins, revealing evolutionary trade-offs between growth, reproduction, and suppression. This study argues that prioritizing fossil collection preservation is crucial, future advances molecular techniques will allow deeper insights into disease evolution. By integrating theory with paleopathology, we can better understand selective pressures shaped extinct species identify potential mechanisms tumor resistance. commentary necessity long-term conservation efforts support breakthroughs biology comparative oncology.

Language: Английский

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