Circadian Oscillation of Leukocyte Subpopulations and Inflammatory Cytokines over a 24-H Period in Horses DOI Creative Commons
Francesca Aragona, Maria Antonietta Rizzo, Elisabetta Giudice

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 386 - 386

Published: April 20, 2025

The objective of the present study was to investigate influence daily rhythms on immune and inflammatory systems in horses, considering white blood cell count (WBCs), leukocyte subpopulations (neutrophils, basophils, eosinophils, lymphocytes, monocytes), CD4+, CD8+ lymphocyte populations, interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α). Ten Italian Saddle horses (7–12 years old, body weight 480 ± 30 kg) underwent sampling every 4 h over a 24-h period. COSINOR method used identify their parameters. A one-way analysis variance (ANOVA) applied differences acrophase robustness, multiple correlation model (Pearson) evaluate relationships among investigated WBCs, subpopulations, CD8+, IL-1β, IL-6, TNFα exhibited rhythmicity. In particular, IL-6 reached acrophases during dark phase, while neuthrophils, showed diurnal acrophase. One-way ANOVA statistical difference parameters (p < 0.0001). Pearson matrix positive negative Circadian should be taken into consideration with fluctuations biomarkers develop good management practices improve welfare horses.

Language: Английский

Modeling climate change effects on some biochemical parameters in horse DOI
Ömer Deniz, Francesca Aragona,

Gaetana Pezzino

et al.

Research in Veterinary Science, Journal Year: 2025, Volume and Issue: unknown, P. 105630 - 105630

Published: March 1, 2025

Language: Английский

Citations

1
Circadian Oscillation of Leukocyte Subpopulations and Inflammatory Cytokines over a 24-H Period in Horses DOI Creative Commons
Francesca Aragona, Maria Antonietta Rizzo, Elisabetta Giudice

et al.

Veterinary Sciences, Journal Year: 2025, Volume and Issue: 12(4), P. 386 - 386

Published: April 20, 2025

The objective of the present study was to investigate influence daily rhythms on immune and inflammatory systems in horses, considering white blood cell count (WBCs), leukocyte subpopulations (neutrophils, basophils, eosinophils, lymphocytes, monocytes), CD4+, CD8+ lymphocyte populations, interleukin-1β (IL-1β), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α). Ten Italian Saddle horses (7–12 years old, body weight 480 ± 30 kg) underwent sampling every 4 h over a 24-h period. COSINOR method used identify their parameters. A one-way analysis variance (ANOVA) applied differences acrophase robustness, multiple correlation model (Pearson) evaluate relationships among investigated WBCs, subpopulations, CD8+, IL-1β, IL-6, TNFα exhibited rhythmicity. In particular, IL-6 reached acrophases during dark phase, while neuthrophils, showed diurnal acrophase. One-way ANOVA statistical difference parameters (p < 0.0001). Pearson matrix positive negative Circadian should be taken into consideration with fluctuations biomarkers develop good management practices improve welfare horses.

Language: Английский

Citations

0