Drug resistance and genotyping studies of Salmonella Enteritidis isolated from broiler chickens in Iran
Frontiers in Veterinary Science,
Journal Year:
2025,
Volume and Issue:
12
Published: Feb. 18, 2025
Poultry
products
are
considered
an
important
source
of
Salmonella
infections.
Transmission
non-typhoidal
enterica
serovars
to
humans
has
been
a
great
concern
worldwide.
Occurrence
multi-drug
resistance,
adding
the
presence
various
virulence
factors,
which
facilitate
pathogenesis
Salmonella,
would
cause
tremendous
risk
for
both
human
and
animals'
health.
During
2023,
out
total
number
1,274
samples
from
broilers
in
Iran,
114
isolates
spp.
(8.94%)
were
detected
97
confirmed
as
Enteritidis
(SE).
Eight
genes
including
invA,
sefA,
sopE,
spvC,
hilA,
agfA,
sivH
lpfA,
among
SE
it
was
found
that
all
harbored
these
at
rate
100%
except
present
96.90%
isolates.
In
phenotypic
evaluation
resistance
against
16
antimicrobial
agents,
high
rates
observed
nalidixic
acid,
ampicillin,
amoxicillin-clavulanate
ciprofloxacin.
While
tetracycline,
streptomycin
chloramphenicol
be
moderate,
very
low
azithromycin,
sulfamethoxazole-trimethoprim,
amikacin,
gentamicin,
ceftriaxone
cefotaxime.
However,
sensitive
meropenem,
ceftazidime
aztreonam.
The
mean
MAR
index
values
0.26
72.15%
highly
resistant.
detection
14
isolates,
five
blaTEM,
tetA,
tetB,
sul1
strA/B
with
prevalence
63.92,
36.08,
61.85,
10.30
14.43%,
respectively.
MDR
SE,
along
overwhelming
major
factors
raise
public
health
concerns.
These
data
highlight
potential
risks
transmission
pathogenic
chicken
meat
sources,
well
need
more
effective
surveillance
use
poultry
industry.
Reducing/optimizing
antimicrobials,
improving
management
procedures,
using
probiotics
biosecurity
or
vaccines
essential
deal
this
issue.
Language: Английский
Antimicrobial Resistance Gene Profiles in Communities Selected with Novel and Previously Encountered Antibiotics
H.L. Cheng
No information about this author
Theoretical and Natural Science,
Journal Year:
2025,
Volume and Issue:
89(1), P. 78 - 85
Published: Jan. 15, 2025
Antibiotics
are
extensively
employed
worldwide
for
therapeutic
purposes,
often
leading
to
overuse,
which
constitutes
a
contributing
factor
the
emergence
of
antibiotic
resistance
(ABR).
This
phenomenon
arises
from
diminished
effectiveness
antibiotics
in
treating
bacterial
infections
due
development.
However,
limitations
experimental
conditions
and
equipment
making
it
challenging
pinpoint
precise
sources
resistance,
consequently
constraining
breadth
research
on
ABR.
Genomic
analysis
antibiotic-resistant
bacteria
assists
unveiling
origins
pathways
dissemination.
study
employs
Nanopore-based
metagenomic
sequencing,
enabling
direct
sequencing
microbial
DNA
within
macrogenomic
samples,
thereby
yielding
comprehensive
sequence
data.
Coupled
with
qPCR
16S
rRNA
gene
datasets,
this
approach
facilitates
exploration
distribution
prevalence
communities
across
different
environments
Focusing
Scottish
farmlands,
isolated
colonies
were
exposed
(sulfamonomethoxine
erythromycin)
several
weeks.
By
comparing
them
untreated
control
group
microorganisms,
identification
genes
(ABRGs),
along
their
variations
abundance,
aims
analyse
impact
these
two
species.
Language: Английский
Bioactive compounds from sea sponges in Tobago exhibit growth inhibitory activity against Staphylococcus aureus and Escherichia coli compared to Amoxiclav
Journal of Taibah University for Science,
Journal Year:
2025,
Volume and Issue:
19(1)
Published: Feb. 10, 2025
Language: Английский
Pollution by Antimicrobials and Antibiotic Resistance Genes in East Africa: Occurrence, Sources, and Potential Environmental Implications
Miraji Hossein,
No information about this author
Asha Ripanda
No information about this author
Toxicology Reports,
Journal Year:
2025,
Volume and Issue:
14, P. 101969 - 101969
Published: Feb. 22, 2025
Language: Английский
A systematic literature review on integrated livestock systems using machine learning methods: strengths and future directions from an animal welfare perspective within the “one health” approach
Annalisa Previti,
No information about this author
Vito Biondi,
No information about this author
Diego Antonio Sicuso
No information about this author
et al.
Journal of Consumer Protection and Food Safety,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 27, 2025
Language: Английский
Design, Synthesis, and Bioactivity Evaluation of Novel Sulfone Derivatives Incorporating an 1,2,4-Triazole Moiety
Russian Journal of General Chemistry,
Journal Year:
2025,
Volume and Issue:
95(3), P. 757 - 763
Published: March 1, 2025
Language: Английский
Fungi for Sustainable Pharmaceutical Remediation: Enzymatic Innovations, Challenges, and Applications—A Review
Processes,
Journal Year:
2025,
Volume and Issue:
13(4), P. 1034 - 1034
Published: March 31, 2025
The
extensive
use
of
pharmaceuticals
in
human
and
veterinary
medicine
has
led
to
their
persistent
environmental
release,
posing
ecological
public
health
risks.
Major
sources
include
manufacturing
effluents,
excretion,
aquaculture,
improper
disposal,
contributing
bioaccumulation
ecotoxicity.
Mycoremediation
is
the
fungal-mediated
biodegradation
pharmaceuticals,
offers
a
promising
sustainable
approach
mitigate
pharmaceutical
pollution.
Studies
have
reported
that
certain
fungal
species,
including
Trametes
versicolor
Pleurotus
ostreatus,
can
degrade
up
90%
contaminants,
such
as
diclofenac,
carbamazepine,
ibuprofen,
within
days
weeks,
depending
on
conditions.
Fungi
produce
range
extracellular
enzymes,
laccases
peroxidases,
alongside
intracellular
enzymes
like
cytochrome
P450
monooxygenases,
which
catalyze
transformation
complex
compounds.
These
play
an
essential
role
modifying,
detoxifying,
mineralizing
xenobiotics,
thereby
reducing
persistence
toxicity.
effectiveness
biotransformation
influenced
by
factors
substrate
specificity,
enzyme
stability,
Optimal
degradation
typically
occurs
at
pH
4.5–6.0
temperatures
20–30
°C.
Recent
advancements
engineering,
immobilization
techniques,
bioreactor
design
improved
catalytic
efficiency
process
feasibility.
However,
scaling
fungal-based
remediation
systems
for
large-scale
applications
remains
challenge.
Addressing
these
limitations
with
synthetic
biology,
metabolic
other
biotechnological
innovations
could
further
enhance
enzymatic
pharmaceuticals.
This
review
highlights
innovations,
applications,
challenges
mycoremediation,
emphasizing
potential
fungi
transformative
solution
waste
management.
Language: Английский
Assessment of inappropriate use of antibiotics and contributing factors in Awi Administrative Zone, Northwestern Amhara Regional State, Ethiopia
New Microbes and New Infections,
Journal Year:
2024,
Volume and Issue:
63, P. 101557 - 101557
Published: Dec. 20, 2024
Language: Английский