International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 311, P. 143847 - 143847
Published: May 1, 2025
Language: Английский
Journal of Crop Science and Biotechnology, Journal Year: 2022, Volume and Issue: 26(1), P. 13 - 26
Published: June 21, 2022
Language: Английский
Citations
22
Pharmaceuticals, Journal Year: 2024, Volume and Issue: 17(6), P. 786 - 786
Published: June 15, 2024
Crataegus monogyna (C. monogyna) is a prominent plant used in Moroccan traditional medicine. This study investigated the phenolic composition and anti-inflammatory, hepatoprotective, anticancer activities of hydroethanolic extract C. leaves stems. Ultra-high-performance liquid chromatography identified profile. The vitro activity was evaluated using MTT assay on HL-60 K-562 myeloleukemia cells liver (Huh-7) cell lines. anti-inflammatory effect assessed vivo carrageenan-induced paw edema rats. hepatoprotective at 300 1000 mg/kg doses against acetaminophen-induced hepatotoxicity rats studied for seven days. Additionally, molecular docking simulations were performed to evaluate extract’s inhibitory potential key targets: lipoxygenase, cytochrome P450, tyrosine kinase, TRADD. exhibited significant cytotoxic cells, but not lung cancer (Huh-7 line). dose demonstrated most potent effect, inhibiting by 99.10% after 6 h. displayed promising properties. Procyanidin (−7.27 kcal/mol), quercetin (−8.102 catechin (−9.037 kcal/mol) as active molecules respectively. These findings highlight untapped further exploration treating damage, inflammation, leukemia.
Language: Английский
Citations
4
Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 375, P. 124267 - 124267
Published: Jan. 29, 2025
Language: Английский
Citations
0
Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 315 - 335
Published: Jan. 1, 2025
Language: Английский
Citations
0
Journal of Food Process Engineering, Journal Year: 2025, Volume and Issue: 48(2)
Published: Feb. 1, 2025
ABSTRACT This research investigates the optimization of carotenoid extraction from Citrus clementina peels using Ultrasonic‐Microwave‐assisted (U‐MAE) and evaluates their biological activities. The study employs Response surface methodology (RSM) to determine optimal parameters (hexane percentage in hexane/acetone mixture, sonication time, irradiation time) that yielded highest total content (TCC) with high antioxidant activity (TAA) assess impact each parameter on responses. Additionally, capacity, anti‐inflammatory, antidiabetic, antimicrobial activities were analyzed vitro spectrophotometric methods. results demonstrate a significant positive correlation between hexane both TCC TAA. Furthermore, revealed shorter times led important increases assessed effect particle size TAA, showing finer sizes resulted higher activity. carotenoid‐rich extract exhibited robust antioxidant, antidiabetic activities, as well notable antibacterial antifungal properties, suggesting its potential application substitute for synthetic counterparts various industries, including food pharmaceuticals. Overall, this provides valuable insights into bioactivity carotenoids C. peels.
Language: Английский
Citations
0
Current Food Science and Technology Reports, Journal Year: 2025, Volume and Issue: 3(1)
Published: Feb. 5, 2025
Language: Английский
Citations
0
Applied Food Research, Journal Year: 2025, Volume and Issue: 5(1), P. 100763 - 100763
Published: Feb. 11, 2025
Language: Английский
Citations
0
Molecules, Journal Year: 2025, Volume and Issue: 30(5), P. 1115 - 1115
Published: Feb. 28, 2025
By-products of fruit processing may contain bioactive compounds with potential application as bioinputs. This study optimized the ultrasound-assisted extraction (UAE) phenolic from by-products Eugenia dysenterica DC (Myrtaceae) to obtain bioinputs antioxidant, antimicrobial, and antibiofilm activities. The (seeds peels) were subjected UAE optimization using Box–Behnken design response surface methodology. Two optimal conditions defined: 1-plant material/solvent ratio 0.01 g/mL, time 40 min, ethanol content 30%; 2–0.19 39 46%. (liquid extract—LQE; lyophilized extract—LYE), obtained under conditions, tested for antioxidant activity (ABTS, FRAP, DPPH). LQE: 1633.13 µM Trolox/g, 1633.60 FeSO4/g 73.35 g sample/g DPPH; LYE: 1379.75 1692.09 83.35 DPPH. For antimicrobial activity, both extracts presented MBC < 62.5 mg/mL MIC 2.5 P. aeruginosa. LQE action S. coagulase (50 mg/mL) Streptococcus spp. (12.5 mg/mL); LYE aeruginosa mg/mL; 12.5 mg/mL), E. coli (25 mg/mL). by present
Language: Английский
Citations
0
Scientific Reports, Journal Year: 2025, Volume and Issue: 15(1)
Published: March 18, 2025
Abstract The influence of nano-encapsulated Yucca schidigera extract (YSE) on total gas (GP), ruminal methane (CH 4 ), carbon monoxide (CO), hydrogen sulphide (H 2 S) production, and fermentation activities diets based two different protein levels were investigated. A completely randomized experimental design with a factorial arrangement (2 × 4) three replications was used. Factor 1 the dietary (14%and 18%), factor types extracts used (TE; negative control (without extract), positive (empty chitosan nano-capsules), Y. nano-capsules, crude 3 doses each type (ED; 0-, 0.25-, 0.5-, 1.0- mL extract/g DM). Nano-chitosan reduced GP production higher level by 24.9% after 48 h while elevated it. At both levels, interaction at an ED 0.25 DM generated volume CH 6 ( p = 0.001 respectively) compared to control. for nano-extract elicited lower CO < 0.0001), respectively. resulted in less H S produced than when same dose 0.027). did not significantly affect any parameters under consideration as levels. However, TE affected pH dry matter degradability 0.0001) impacted :SCFA :ME 0.045) values obtained nano-chitosan control, In conclusion, proved its antimicrobial property, although increased 14% protein, vitro indicated ability minimize GP, rumen, boost conversion efficiency.
Language: Английский
Citations
0
Waste and Biomass Valorization, Journal Year: 2025, Volume and Issue: unknown
Published: April 1, 2025
Language: Английский
Citations
0